Professor Cristin Print

BHB, MBChB, PhD

Professor

In: Molecular Medicine and Pathology » Medical Science » Faculty of Medical and Health Sciences

Biography

Cris graduated in Medicine from the University of Auckland in 1989. He worked as a house surgeon and undertook asthma research in Dunedin before completing a Immunology PhD in Auckland under Professor Jim Watson and Dr Geoff Krissansen. He used transgenic technologies to research apoptosis in Melbourne, Australia, before moving to Cambridge University, UK, where he used genomics to research angiogenesis and reproduction, and was a fellow of St Edmund’s College. He co-founded a public genomics and bioinformatics company in Japan before returning to New Zealand in 2005 where he has been using genomics to better understand human pathology, with special focus on cancer. Cris leads the Genomics Into Medicine program in Auckland. He is currently a Professor in the University's Department of Molecular Medicine and Pathology, a Principal Investigator in the Maurice Wilkins Centre, on the Science Leadership Team of the Healthier Lives National Science Challenge, Chair of Scientific Advisory Board of the Auckland Regional Tissue Bank and Vice President of the Auckland Museum Institute. He is past Director of the NZ Bioinformatics Institute and immediate past President of the New Zealand Society for Oncology.

Research | Current

Research group

Bioinformatics of Disease

Research interests

Clinical Genomics
Bioinformatics
Systems Biology
Cancer

Selected publications and creative works (Research Outputs)

McKeown, C., Connors, S., Stapleton, R., Morgan, T., Hayes, I., Neas, K., ... Tsai, P. (2018). A pilot study of exome sequencing in a diverse New Zealand cohort with undiagnosed disorders and cancer. Journal of the Royal Society of New Zealand, 1-18. 10.1080/03036758.2018.1464033
Other University of Auckland co-authors: Ben Lawrence, Peter Tsai, Cherie Blenkiron
Evans, G. E., Phillipson, G. T. M., Sykes, P. H., McNoe, L. A., Print, C. G., & Evans, J. J. (2018). Does the endometrial gene expression of fertile women vary within and between cycles?. Human reproduction (Oxford, England)10.1093/humrep/dex385
Campbell, H., Fleming, N., Roth, I., Mehta, S., Wiles, A., Williams, G., ... Pajic, M. (2018). ∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling. Nature communications, 9 (1)10.1038/s41467-017-02408-0
Lawrence, B., Blenkiron, C., Parker, K., Tsai, P., Fitzgerald, S., Shields, P., ... James, S. M. (2017). Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer. 10.1101/214585 https://www.biorxiv.org/content/early/2017/11/08/214585.
Other University of Auckland co-authors: Ben Lawrence, Cherie Blenkiron, Kate Parker, Tamsin Robb, Nooriyan Poonawala-Lohani, Braden Woodhouse, Kimi Henare, Marianne Elston, Papaarangi Reid, John Windsor, Andrew MacCormick, Adam Bartlett, Michael Findlay
Muthukaruppan, A., Lasham, A., Blenkiron, C., Woad, K. J., Black, M. A., Knowlton, N., ... Shelling, A. N. (2017). Gene expression profiling of breast tumours from New Zealand patients. New Zealand Medical Journal, 130 (1464), 40-56.
Other University of Auckland co-authors: Michael Findlay, Annette Lasham, Cherie Blenkiron, Andrew Shelling, Anita Muthukaruppan
Tran, B., Hunter, F., Jamieson, S., Kolekar, S., Li, D., Kakadiya, P., ... Bohlander, S. K. (14/10/2017). Preclinical efficacy and sensitivity determinants of statins in molecularly-defined models of melanoma. Poster presented at New Zealand Society for Oncology Conference, Auckland, New Zealand.
Other University of Auckland co-authors: Francis Hunter, Khanh Tran, Stephen Jamieson, Purvi Kakadiya, William Wilson, Stefan Bohlander, Bruce Baguley, Peter Shepherd
Siemens, K., Khan, A., Tsai, P., Kakadiya, P. N., Dixon-McIver, A., Ng, D., ... Harvey, V. J. (14/10/2017). Use of CRISPR-mediated functional genomics to understand resistance to targeted therapies in HER2-positive breast cancer. Poster presented at New Zealand Society for Oncology Conference, Auckland, New Zealand.
Other University of Auckland co-authors: Francis Hunter, Purvi Kakadiya, Stefan Bohlander, William Wilson
Lee, T. W. (14/10/2017). Development of a tumour xenograft model for genome-wide CRISPR/Cas9 screens. Poster presented at New Zealand Society for Oncology Conference 2017, Auckland, New Zealand.
Other University of Auckland co-authors: Tet Woo Lee, Francis Hunter, Peter Tsai, Purvi Kakadiya, Avik Shome, Courtney Lynch, Stefan Bohlander, William Wilson, Stephen Jamieson