Emeritus Professor Lynnette Robin Ferguson

D.Phil. (Oxon.), DSc., QSO, FNZIFST, FRSNZ

Biography

Lynnette Ferguson obtained her D.Phil.(Oxon) (the equivalent of a PhD) from Oxford University, working on the subject of DNA damage, DNA repair and mutagenesis in yeast. After her return to New Zealand, she began working as part of the Auckland Cancer Society Research Centre, using mutagenicity testing as a predictor of carcinogenesis, with particular focus on the New Zealand situation. In 2000, she took on a 50% role as Head of a new Discipline of Nutrition at the University of Auckland. In more recent years, she has considered the interplay between genes and diet in the development of chronic disease, with particular focus on Inflammatory Bowel Disease, a cancer-prone condition, and also in prostate cancer. As programme leader for the multidisciplinary-multiorganisation Nutrigenomics New Zealand, she worked with a range of others to bring nutrigenomics tools and potential to the New Zealand science scene. She has supervised more than 40 students to the successful completion of B.tech, MSc or PhD. Her laboratory regularly supervises 2-3 summer students each year. She is the author or co-author of more than 350 peer reviewed publications as chapters in books or articles in international journals. She serves on the Editorial Boards of several major journals.

Research | Current

Lynnette's current research considers the interplay between genes and diet in the development of chronic disease, with particular focus on Inflammatory Bowel Disease, a cancer-prone condition and also in both colorectal and prostate cancer.   As programme leader for the multidisciplinary-multiorganisation Nutrigenomics New Zealand, she has worked with a range of others across The university of Auckland, Plant and Food Research and Agresearch Ltd, to bring nutrigenomics tools and potential to the New Zealand science scene. http://www.nutrigenomics.org.nz/ Research interests: Gene-diet interactions in the development of chronic disease, Inflammatory Bowel Diseases, Colorectal cancer, Prostate cancer

Teaching | Current

Offers projects for MEDSCI701 and 702, co-supervises MSc and PhD projects

Distinctions/Honours

Queens Service Order in Public Health

Fellow, New Zealand Institute of Food Science and Technology

Fellow, Royal Society of New Zealand

Selected publications and creative works (Research Outputs)

  • Ferguson, L. R., Karunasinghe, N., & Vaidayanathan, V. (2018). Genomic Instability and Prostate Cancer Risk in New Zealand. Paper presented at 49th Annual Meeting of the Environmental-Mutagenesis-and-Genomics-Society (EMGS) - Maintaining Genomic Integrity in the Face of Environmental Insult, San Antonio, TX. 22 September - 26 September 2018. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. (pp. 1).
  • Peng, Y., Bishop, K. S., Ferguson, L. R., & Quek, S. Y. (2018). Screening of Cytotoxicity and Anti-Inflammatory Properties of Feijoa Extracts Using Genetically Modified Cell Models Targeting TLR2, TLR4 and NOD2 Pathways, and the Implication for Inflammatory Bowel Disease. Nutrients, 10 (9).10.3390/nu10091188
    Other University of Auckland co-authors: Karen Bishop, Siew-Young Quek
  • Momozawa, Y., Dmitrieva, J., Théâtre E, Deffontaine, V., Rahmouni, S., Charloteaux, B., ... Gori, A.-S. (2018). IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes. Nature communications, 9 (1)10.1038/s41467-018-04365-8
  • Ordovas, J. M., Ferguson, L. R., Tai, E. S., & Mathers, J. C. (2018). Personalised nutrition and health. BMJ (Clinical research ed.), 36110.1136/bmj.k2173
  • Vaidyanathan, V., Naidu, V., Kao, C. H.-J., Karunasinghe, N., Prasanna, K., Pallati, R., ... Narayanan, A. (2018). Aggressive and Non-Aggressive Prostate Cancer: Two Sides of the Same Coin or Two Different Coins?. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY. (pp. 2).
    URL: http://hdl.handle.net/2292/42586
    Other University of Auckland co-authors: Nishi Karunasinghe
  • Karunasinghe, N., Ambs, S., Wang, A., Tang, W., Zhu, S., Dorsey, T. H., ... Ferguson, L. R. (2018). Influence of lifestyle and genetic variants in the aldo-keto reductase 1C3 rs12529 polymorphism in high-risk prostate cancer detection variability assessed between US and New Zealand cohorts. PloS one, 13 (6)10.1371/journal.pone.0199122
    Other University of Auckland co-authors: Nishi Karunasinghe
  • Piazzolla, V., Panunzio, M. F., Caporizzi, R., Cela, E. P., Di Martino, V., Antoniciello, A., ... Conversano, M. (2018). "Five-A-Day" and the Med-Food Anticancer Program. Annali di igiene : medicina preventiva e di comunita, 20 (1), 73-74. 10.7416/ai.2018.2199
  • Ferguson, L. R. (2017). Why might the finding of a new genetic association with inflammatory bowel disease be of potential value in disease control?. The American journal of clinical nutrition, 106 (6), 1335-1336. 10.3945/ajcn.117.169623