Dr Daniel Plimmer Furkert

PhD

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Senior Research Fellow

Biography

Dan gained his PhD in chemistry in 2003 (UoA), followed by NIH postdoctoral fellowships at Oregon State University (USA) working on natural product total synthesis, and then in the Dept of Pharmacy & Pharmacology at the University of Bath (UK) investigating novel opioid receptor ligands for treatment of drug abuse.

He returned to UoA in 2010 to take up his current position as team leader of Dist Prof Margaret Brimble's organicsynthesis labs.

Research | Current

Current research themes include organic synthesis directed towards natural products and drug discovery, development of improved chemical methods to access biologically relevant structures, and medicinal chemistry focused on TB, cancer and neuropharmacology.

Teaching | Current

Lectures in CHEM330, CHEM730 

Selected publications and creative works (Research Outputs)

  • Grant, P. S., Kahlcke, N., Govindpani, K., Hunter, M., MacDonald, C., Brimble, M. A., ... Furkert, D. P. (2019). Divalent cannabinoid-1 receptor ligands: A linker attachment point survey of SR141716A for development of high-affinity CB1R molecular probes. Bioorganic & medicinal chemistry letters10.1016/j.bmcl.2019.126644
    Other University of Auckland co-authors: Michelle Glass, Karan Govindpani, Margaret Brimble
  • Freeman, J. L., Brimble, M. A., & Furkert, D. P. (2019). A chiral auxiliary-based synthesis of the C5-C17 trans-decalin framework of anthracimycin. ORGANIC CHEMISTRY FRONTIERS, 6 (16), 2954-2963. 10.1039/c9qo00769e
    Other University of Auckland co-authors: Margaret Brimble
  • Ding, X.-B., Furkert, D. P., & Brimble, M. A. (2019). Highly Diastereoselective Synthesis of Syn-1,3-Dihydroxyketone Motifs from Propargylic Alcohols via Spiroepoxide Intermediates. Angewandte Chemie (International ed. in English), 58 (34), 11830-11835. 10.1002/anie.201905736
    Other University of Auckland co-authors: Margaret Brimble
  • Daniels, B. J., Li, F. F., Furkert, D. P., & Brimble, M. A. (2019). Naturally Occurring Lumazines. Journal of natural products, 82 (7), 2054-2065. 10.1021/acs.jnatprod.9b00351
    Other University of Auckland co-authors: Margaret Brimble
  • Grant, P. S., Brimble, M. A., & Furkert, D. P. (2019). Synthesis of the Bicyclic Lactone Core of Leonuketal, Enabled by a Telescoped Diels-Alder Reaction Sequence. Chemistry, an Asian journal, 14 (8), 1128-1135. 10.1002/asia.201800903
    Other University of Auckland co-authors: Margaret Brimble
  • Freeman, J. L., Brimble, M. A., & Furkert, D. P. (2019). Convenient access to 5-membered cyclic iminium ions: evidence for a stepwise [4 + 2] cycloaddition mechanism. Organic & biomolecular chemistry, 17 (10), 2705-2714. 10.1039/c9ob00262f
    Other University of Auckland co-authors: Margaret Brimble
  • Wood, J. M., Furkert, D. P., & Brimble, M. A. (2019). 2-Formylpyrrole natural products: origin, structural diversity, bioactivity and synthesis. Natural product reports, 36 (2), 289-306. 10.1039/c8np00051d
    Other University of Auckland co-authors: Margaret Brimble
  • Ding, X.-B., Brimble, M. A., & Furkert, D. P. (2018). Reactivity of 2-Nitropyrrole Systems: Development of Improved Synthetic Approaches to Nitropyrrole Natural Products. The Journal of organic chemistry, 83 (20), 12460-12470. 10.1021/acs.joc.8b01692
    Other University of Auckland co-authors: Margaret Brimble

Contact details

Primary office location

SCIENCE CENTRE - CHEMISTRY - Bldg 301
Level 7, Room 729A
23 SYMONDS ST
AUCKLAND 1010
New Zealand