Dr Daniel Plimmer Furkert

PhD

Senior Research Fellow

In: Chemical Sciences » Faculty of Science

Biography

Dan gained his PhD in chemistry in 2003 (UoA), followed by NIH postdoctoral fellowships at Oregon State University (USA) working on natural product total synthesis, and then in the Dept of Pharmacy & Pharmacology at the University of Bath (UK) investigating novel opioid receptor ligands for treatment of drug abuse.

He returned to UoA in 2010 to take up his current position as team leader of Dist Prof Margaret Brimble's organicsynthesis labs.

Research | Current

Current research themes include organic synthesis directed towards natural products and drug discovery, development of improved chemical methods to access biologically relevant structures, and medicinal chemistry focused on TB, cancer and neuropharmacology.

Teaching | Current

Lectures in CHEM330, CHEM730

Selected publications and creative works (Research Outputs)

Grant, P. S., Kahlcke, N., Govindpani, K., Hunter, M., MacDonald, C., Brimble, M. A., ... Furkert, D. P. (2019). Divalent cannabinoid-1 receptor ligands: A linker attachment point survey of SR141716A for development of high-affinity CB1R molecular probes. Bioorganic & medicinal chemistry letters10.1016/j.bmcl.2019.126644
Other University of Auckland co-authors: Michelle Glass, Karan Govindpani, Margaret Brimble
Freeman, J. L., Brimble, M. A., & Furkert, D. P. (2019). A chiral auxiliary-based synthesis of the C5-C17 trans-decalin framework of anthracimycin. ORGANIC CHEMISTRY FRONTIERS, 6 (16), 2954-2963. 10.1039/c9qo00769e
Other University of Auckland co-authors: Margaret Brimble
Ding, X.-B., Furkert, D. P., & Brimble, M. A. (2019). Highly Diastereoselective Synthesis of Syn-1,3-Dihydroxyketone Motifs from Propargylic Alcohols via Spiroepoxide Intermediates. Angewandte Chemie (International ed. in English), 58 (34), 11830-11835. 10.1002/anie.201905736
Other University of Auckland co-authors: Margaret Brimble
Daniels, B. J., Li, F. F., Furkert, D. P., & Brimble, M. A. (2019). Naturally Occurring Lumazines. Journal of natural products, 82 (7), 2054-2065. 10.1021/acs.jnatprod.9b00351
Other University of Auckland co-authors: Margaret Brimble
Grant, P. S., Brimble, M. A., & Furkert, D. P. (2019). Synthesis of the Bicyclic Lactone Core of Leonuketal, Enabled by a Telescoped Diels-Alder Reaction Sequence. Chemistry, an Asian journal, 14 (8), 1128-1135. 10.1002/asia.201800903
Other University of Auckland co-authors: Margaret Brimble
Freeman, J. L., Brimble, M. A., & Furkert, D. P. (2019). Convenient access to 5-membered cyclic iminium ions: evidence for a stepwise [4 + 2] cycloaddition mechanism. Organic & biomolecular chemistry, 17 (10), 2705-2714. 10.1039/c9ob00262f
Other University of Auckland co-authors: Margaret Brimble
Wood, J. M., Furkert, D. P., & Brimble, M. A. (2019). 2-Formylpyrrole natural products: origin, structural diversity, bioactivity and synthesis. Natural product reports, 36 (2), 289-306. 10.1039/c8np00051d
Other University of Auckland co-authors: Margaret Brimble
Ding, X.-B., Brimble, M. A., & Furkert, D. P. (2018). Reactivity of 2-Nitropyrrole Systems: Development of Improved Synthetic Approaches to Nitropyrrole Natural Products. The Journal of organic chemistry, 83 (20), 12460-12470. 10.1021/acs.joc.8b01692
Other University of Auckland co-authors: Margaret Brimble