Dr Daniel Plimmer Furkert

PhD

Senior Research Fellow

In: Chemical Sciences » Faculty of Science

Biography

Dan gained his PhD in chemistry in 2003 (UoA), followed by NIH postdoctoral fellowships at Oregon State University (USA) working on natural product total synthesis, and then in the Dept of Pharmacy & Pharmacology at the University of Bath (UK) investigating novel opioid receptor ligands for treatment of drug abuse.

He returned to UoA in 2010 to take up his current position as team leader of Dist Prof Margaret Brimble's organicsynthesis labs.

Research | Current

Current research themes include organic synthesis directed towards natural products and drug discovery, development of improved chemical methods to access biologically relevant structures, and medicinal chemistry focused on TB, cancer and neuropharmacology.

Teaching | Current

Lectures in CHEM330, CHEM730

Selected publications and creative works (Research Outputs)

Calvert, M. B., Furkert, D. P., Cooper, C. B., & Brimble, M. A. (2020). Synthetic approaches towards bedaquiline and its derivatives. Bioorganic & medicinal chemistry letters, 30 (12)10.1016/j.bmcl.2020.127172
Other University of Auckland co-authors: Margaret Brimble
Freeman, J. L., Li, F. F., Furkert, D. P., & Brimble, M. A. (2020). Synthetic Studies Towards Spirocyclic Imine Marine Toxins Using N -Acyl Iminium Ions as Dienophiles in Diels-Alder Reactions. SYNLETT, 31 (7), 657-671. 10.1055/s-0039-1691593
Other University of Auckland co-authors: Margaret Brimble, Freda Li
Aitken, H. R. M., Brimble, M. A., & Furkert, D. P. (2020). A Catalytic Asymmetric Ene Reaction for Direct Preparation of alpha-Hydroxy 1,4-Diketones as Intermediates in Natural Product Synthesis. SYNLETT, 31 (7), 687-690. 10.1055/s-0037-1610748
Other University of Auckland co-authors: Margaret Brimble
Lin, B., Daniels, B. J., Middleditch, M. J., Furkert, D. P., Brimble, M. A., Bong, J., ... Loomes, K. M. (2020). Utility of the Leptospermum scoparium Compound Lepteridine as a Chemical Marker for Manuka Honey Authenticity. ACS OMEGA, 5 (15), 8858-8866. 10.1021/acsomega.0c00486
Other University of Auckland co-authors: Martin Middleditch, Margaret Brimble, Kerry Loomes
Choi, H., Shirley, H. J., Aitken, H. R. M., Schulte, T., Söhnel T, Hume, P. A., ... Furkert, D. P. (2020). Intermolecular Diels-Alder Cycloaddition/Cross-Coupling Sequences of 2-Bromo-1,3-butadienes. Organic letters, 22 (3), 1022-1027. 10.1021/acs.orglett.9b04567
Other University of Auckland co-authors: Margaret Brimble, Tilo Söhnel
Grant, P. S., Kahlcke, N., Govindpani, K., Hunter, M., MacDonald, C., Brimble, M. A., ... Furkert, D. P. (2019). Divalent cannabinoid-1 receptor ligands: A linker attachment point survey of SR141716A for development of high-affinity CB1R molecular probes. Bioorganic & medicinal chemistry letters, 29 (21)10.1016/j.bmcl.2019.126644
URL: http://hdl.handle.net/2292/48827
Other University of Auckland co-authors: Michelle Glass, Karan Govindpani, Margaret Brimble
Freeman, J. L., Brimble, M. A., & Furkert, D. P. (2019). A chiral auxiliary-based synthesis of the C5-C17 trans-decalin framework of anthracimycin. ORGANIC CHEMISTRY FRONTIERS, 6 (16), 2954-2963. 10.1039/c9qo00769e
Other University of Auckland co-authors: Margaret Brimble
Ding, X.-B., Furkert, D. P., & Brimble, M. A. (2019). Highly Diastereoselective Synthesis of Syn-1,3-Dihydroxyketone Motifs from Propargylic Alcohols via Spiroepoxide Intermediates. Angewandte Chemie (International ed. in English), 58 (34), 11830-11835. 10.1002/anie.201905736
Other University of Auckland co-authors: Margaret Brimble