Professor Mark Hedley Vickers

BSc, MSc (Hons), PhD

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Professor

Biography

Mark's primary interest is in the developmental origins of health and disease with a particular focus on the association between poor maternal nutrition and the development of obesity and type 2 diabetes in offspring.  He also has an interest in therapies aimed at reversing the metabolic disturbances that result from a suboptimal early life environment.

Collaborations:

  • University of Cambridge
  • University of Southampton
  • Singapore Institute for Clinical Sciences and National University of Singapore
  • University of Western Australia
  • McGill University, Montreal, Canada

Personal quote:

“Few other aspects of nutrient supply and metabolism are of greater biological importance than the feeding of mothers during pregnancy and lactation. Our research aims to develop platforms to examine nutrition during these critical windows and optimize the health of mothers and offspring to reduce risk of adult diseases such as obesity and diabetes in adult life.”

 

Research | Current

  • Developmental origins of health and disease
  • Maternal and infant nutrition, obesity, metabolic syndrome, type 2 diabetes

Major grant funding:

  • Health Research Council of NZ (HRC)
  • Gravida: National Centre for Growth and Development
  • Marsden Fund
  • Ministry of Business, Innovation and Employment (MBIE)
  • Auckland Medical Research Foundation

 

Teaching | Current

  • Developmental programming, Stage 3 Physiology
  • MedSci courses 304, 729, 734

Areas of expertise

Maternal nutrition, developmental programming, obesity, metabolic syndrome, pregnancy, diabetes, nutrition, fetal growth

Committees/Professional groups/Services

Associate Dean Research (Liggins Institute)

UARC

Masters Advisory Committee

Postgraduate Studies Committee

Ethics Committee

NZ Representative, DOHaD Society

 

Selected publications and creative works (Research Outputs)

  • Jacobson, E. C., Grand, R. S., Perry, J. K., Vickers, M. H., Olins, A. L., Olins, D. E., & O'Sullivan JM (2019). Hi-C detects novel structural variants in HL-60 and HL-60/S4 cell lines. Genomics10.1016/j.ygeno.2019.05.009
    Other University of Auckland co-authors: Jo Perry
  • Li, F., Liu, K., Wang, A., Harris, P. W. R., Vickers, M. H., & Guan, J. (2019). Cyclic glycine-proline administration normalizes high-fat diet-induced synaptophysin expression in obese rats. Neuropeptides10.1016/j.npep.2019.05.006
    Other University of Auckland co-authors: Jian Guan, Paul Harris
  • Bridge-Comer, P. E., Vickers, M. H., & Reynolds, C. M. (2019). Preclinical Models of Altered Early Life Nutrition and Development of Reproductive Disorders in Female Offspring. Advances in experimental medicine and biology, 1134, 59-87. 10.1007/978-3-030-12668-1_4
    Other University of Auckland co-authors: Clare Reynolds
  • Nyaga, D. M., Vickers, M. H., Jefferies, C., Perry, J. K., & O'Sullivan JM (2018). The genetic architecture of type 1 diabetes mellitus. Molecular and cellular endocrinology, 477, 70-80. 10.1016/j.mce.2018.06.002
    URL: http://hdl.handle.net/2292/45891
    Other University of Auckland co-authors: Jo Perry, Justin O'Sullivan
  • Jacobson, E., Grand, R., Perry, J., Vickers, M., Olins, A., Olins, D., & O’Sullivan J (2018). Hi-C detects novel structural variants in HL-60 and HL-60/S4 cell lines. 10.1101/482208
    Other University of Auckland co-authors: Jo Perry
  • Jacobson, E. C., Perry, J. K., Long, D. S., Olins, A. L., Olins, D. E., Wright, B. E., ... O'Sullivan JM (2018). Migration through a small pore disrupts inactive chromatin organization in neutrophil-like cells. BMC biology, 16 (1)10.1186/s12915-018-0608-2
    URL: http://hdl.handle.net/2292/46266
    Other University of Auckland co-authors: Jo Perry, Justin O'Sullivan
  • Nyaga, D. M., Vickers, M. H., Jefferies, C., Perry, J. K., & O'Sullivan JM (2018). Type 1 Diabetes Mellitus-Associated Genetic Variants Contribute to Overlapping Immune Regulatory Networks. FRONTIERS IN GENETICS, 910.3389/fgene.2018.00535
    URL: http://hdl.handle.net/2292/45762
    Other University of Auckland co-authors: Jo Perry, Justin O'Sullivan
  • Jacobson, E., Jain, L., Perry, J., Vickers, M., Olins, A., Olins, D., & O’Sullivan J (2018). TNF-α differentially regulates cell cycle genes in promyelocytic and granulocytic HL-60/S4 cells. 10.1101/471789
    Other University of Auckland co-authors: Jo Perry

Identifiers

Contact details

Primary office location

M&HS BUILDING 505 - Bldg 505
Level 2, Room 202G
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand

Web links