Dr Anna Claire Giddens
Research Fellow
Dr
Anna
Claire
Giddens
Dr Anna Claire Giddens
https://unidirectory.auckland.ac.nz/profile/a-giddens
Research Fellow
The University of Auckland: Auckland Cancer Society Research Centre
Selected publications and creative works (Research Outputs)
- Gamage, S. A., Giddens, A. C., Tsang, K. Y., Flanagan, J. U., Kendall, J. D., Lee, W.-J., ... Shepherd, P. R. (2017). Synthesis and biological evaluation of sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474. Bioorganic and Medicinal Chemistry, 25 (20), 5859-5874. 10.1016/j.bmc.2017.09.025
Other University of Auckland co-authors: Gordon Rewcastle, Swarna Gamage, Bill Denny, Jack Flanagan, Bruce Baguley, Christina Buchanan, Stephen Jamieson, Woo Lee - Rewcastle, G. W., Kolekar, S., Buchanan, C. M., Gamage, S. A., Giddens, A. C., Tsang, K. Y., ... Smith, G. C. (2017). Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors. Oncotarget, 8 (29), 47725-47740. 10.18632/oncotarget.17730
URL: http://hdl.handle.net/2292/34774
Other University of Auckland co-authors: Peter Shepherd, Gordon Rewcastle, Christina Buchanan, Swarna Gamage, Bill Denny, Stephen Jamieson, Woo Lee - Kendall, J., Giddens, A., Tsang, K., Marshall, E., Lill, C., Lee, W.-J., ... Yu, S. (2017). Novel pyrazolo[1,5-a]pyridines with improved aqueous solubility as p110α-selective PI3 kinase inhibitors. Bioorganic and Medicinal Chemistry Letters, 27 (2), 187-190. 10.1016/j.bmcl.2016.11.078
URL: http://hdl.handle.net/2292/34181
Other University of Auckland co-authors: Peter Shepherd, Bill Denny, Christina Buchanan, Bruce Baguley, Gordon Rewcastle, Stephen Jamieson, Woo Lee - Giddens, A. C., Lee, H. H., Lu, G.-L., Miller, C. K., Guo, J., Lewis Phillips, G. D., ... Tercel, M. (2016). Analogues of DNA minor groove cross-linking agents incorporating aminoCBI, an amino derivative of the duocarmycins: Synthesis, cytotoxicity, and potential as payloads for antibody-drug conjugates. Bioorganic & Medicinal Chemistry, 24 (22), 6075-6081. 10.1016/j.bmc.2016.09.068
Other University of Auckland co-authors: Moana Tercel, Leon Lu, Ho Lee, Christian Miller - Lu, G., Tercel, M., Giddens, A., Lee, H., Bonnet, M., Denny, W., ... Stabenb, L. R. (2016). Arming antibodies with DNA cross-linking agents derived from the duocarmycins. Paper presented at The 24th International Symposium on Medicinal Chemistry (EFMC-ISMC-2016), Manchester, UK. 28 August - 1 September 2016. EFMC International Symposium on Medicinal Chemistry Book of Abstracts. Related URL.
URL: http://hdl.handle.net/2292/32939
Other University of Auckland co-authors: Leon Lu, Moana Tercel, Bill Denny - Rewcastle, G. W., Giddens, A. C., Flanagan, J. U., Gamage, S. A., Tsang, K. Y., Kendall, J. D., ... O'Farrell M (2015). Design and discovery of PWT33597 (VDC-597), a dual inhibitor of PI3-kinase alpha and mTOR. Paper presented at 2015 International Chemical Congress of Pacific Basin Societies (Pacifichem), Honolulu, Hawaii, USA. 15 December - 20 December 2015.
Other University of Auckland co-authors: Gordon Rewcastle, Jack Flanagan, Swarna Gamage, Bruce Baguley, Christina Buchanan, Stephen Jamieson, Bill Denny, Peter Shepherd - Giddens, A., Bonnet, M., Lee, H., Lu, G. L., Miller, C. K., Tercel, M., ... Safina, B. (16/12/2015). Potent DNA crosslinking cytotoxins as novel payloads for ADCs. Poster presented at Pacifichem 2015, Honolulu, Hawaii, USA.
Other University of Auckland co-authors: Ho Lee, Leon Lu, Christian Miller, Gordon Rewcastle, Moana Tercel, Bill Denny - Flygare, J. A., Pillow, T. H., Safina, B., Verma, V., Wei, B. Q., Denny, W., ... Miller, C.. 1-(Chloromethyl)-2,3-dihydro-1H-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment. WO 2015/023355 A1 Related URL.
URL: http://hdl.handle.net/2292/27904
Other University of Auckland co-authors: Gordon Rewcastle, Bill Denny, Ho Lee, Leon Lu, Christian Miller, Moana Tercel
-
Faculties, institutes, campuses and library
- Faculty of Arts
- Business School
- National Institute of Creative Arts and Industries
- Faculty of Education and Social Work
- Faculty of Engineering
- Faculty of Law
- Faculty of Medical and Health Sciences
- Faculty of Science
- Liggins Institute
- Auckland Bioengineering Institute
- Campuses
- Libraries and Learning Services
- Auckland UniServices Ltd
- More information...
