Dr Anna Claire Giddens
Research Fellow
Dr
Anna
Claire
Giddens
Dr Anna Claire Giddens
https://unidirectory.auckland.ac.nz/profile/a-giddens
Research Fellow
The University of Auckland: Auckland Cancer Society Research Centre
Selected publications and creative works (Research Outputs)
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Research Outputs profile up to date.
- Jose, J., Spicer, J., Miller, C. K., O'Connor P, Giddens, A., Akhlaghi, H., ... Denny, W. A. (1/4/2019). Development of inhibitors of the pore forming protein perforin for the treatment of leukaemia. Poster presented at 257th ACS National Meeting & Exposition, Orlando, FL, United States. MEDI-0164. Related URL.
Other University of Auckland co-authors: Jiney Jose, Julie Spicer, Bill Denny, Christian Miller - Giddens, A. C., Gamage, S. A., Kendall, J. D., Lee, W.-J., Baguley, B. C., Buchanan, C. M., ... Denny, W. A. (2019). Synthesis and biological evaluation of solubilized sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474. Bioorganic & medicinal chemistry, 27 (8), 1529-1545. 10.1016/j.bmc.2019.02.050
Other University of Auckland co-authors: James Dickson, Swarna Gamage, Christina Buchanan, Woo Lee, Stephen Jamieson, Bill Denny, Gordon Rewcastle - Gamage, S., Giddens, A. C., Tsang, K. Y., Flanagan, J. U., Kendall, J. D., Lee, W. J., ... Shepherd, P. R. (2018). A journey of developing a new class of active and potent PI3Kalpha inhibitors. Paper presented at 30th EORTC-NCI-AACR Symposium, Dublin, IRELAND. 13 November - 16 November 2018. EUROPEAN JOURNAL OF CANCER. (pp. 1).
Other University of Auckland co-authors: Christina Buchanan, Stephen Jamieson, Bill Denny, Gordon Rewcastle - Gamage, S. A., Giddens, A. C., Tsang, K. Y., Flanagan, J. U., Kendall, J. D., Lee, W.-J., ... Shepherd, P. R. (2017). Synthesis and biological evaluation of sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474. Bioorganic and Medicinal Chemistry, 25 (20), 5859-5874. 10.1016/j.bmc.2017.09.025
URL: http://hdl.handle.net/2292/41240
Other University of Auckland co-authors: Gordon Rewcastle, Swarna Gamage, Bill Denny, Jack Flanagan, Christina Buchanan, Stephen Jamieson, Woo Lee - Rewcastle, G. W., Kolekar, S., Buchanan, C. M., Gamage, S. A., Giddens, A. C., Tsang, K. Y., ... Smith, G. C. (2017). Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors. Oncotarget, 8 (29), 47725-47740. 10.18632/oncotarget.17730
Other University of Auckland co-authors: Peter Shepherd, Gordon Rewcastle, Christina Buchanan, Swarna Gamage, Bill Denny, Stephen Jamieson, Woo Lee - Kendall, J., Giddens, A., Tsang, K., Marshall, E., Lill, C., Lee, W.-J., ... Yu, S. (2017). Novel pyrazolo[1,5-a]pyridines with improved aqueous solubility as p110α-selective PI3 kinase inhibitors. Bioorganic and Medicinal Chemistry Letters, 27 (2), 187-190. 10.1016/j.bmcl.2016.11.078
Other University of Auckland co-authors: Peter Shepherd, Bill Denny, Christina Buchanan, Gordon Rewcastle, Stephen Jamieson, Woo Lee - Giddens, A. C., Lee, H. H., Lu, G.-L., Miller, C. K., Guo, J., Lewis Phillips, G. D., ... Tercel, M. (2016). Analogues of DNA minor groove cross-linking agents incorporating aminoCBI, an amino derivative of the duocarmycins: Synthesis, cytotoxicity, and potential as payloads for antibody-drug conjugates. Bioorganic & Medicinal Chemistry, 24 (22), 6075-6081. 10.1016/j.bmc.2016.09.068
URL: http://hdl.handle.net/2292/48826
Other University of Auckland co-authors: Moana Tercel, Leon Lu, Ho Lee, Christian Miller - Lu, G. L., Tercel, M., Giddens, A. C., Lee, H. H., Bonnet, M., Denny, W. A., ... Stabenb, L. R. (2016). Arming antibodies with DNA cross-linking agents derived from the duocarmycins. Paper presented at EFMC International Symposium on Medicinal Chemistry, Manchester, UK. 28 August - 1 September 2016. EFMC International Symposium on Medicinal Chemistry Book of Abstracts.
URL: http://hdl.handle.net/2292/32939
Other University of Auckland co-authors: Leon Lu, Moana Tercel, Bill Denny
Contact details
Primary office location
M&HS BUILDING 504 - Bldg 504
Level 1, Room 126
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand