Miss Alyssa Lesley Lie

BOptom(Hons)

Doctoral Candidate - Doctor of Philosophy

In: Optometry and Vision Science » Faculty of Medical and Health Sciences

Biography

I completed my Bachelors degree with Honours in Optometry at the University of Auckland in 2015 and am therapeutically qualified. Since then I have worked in private practice in Northland and spent time at State University of New York's Optometry college as a visiting doctor. I am currently pursuing a PhD at the University of Auckland full-time and occasionally locum for various optometry and ophthalmology practices.

Research | Current

My research involves the use of Magnetic Resonance Imaging (MRI) to investigate the effect of aging on the physiological optics of the human crystalline lens, with the aim of detecting early biomarkers for cataract onset and progression. This could create opportunities for developing therapeutic treatments to delay or prevent cataract, which may alleviate the financial burden of cataract surgery.

Teaching | Current

OPTOM 216 Lab Tutor

OPTOM 316 Lab Tutor

OPTOM 416 Lab Tutor

Distinctions/Honours

2014 NZAO Paul Dunlop Memorial Research Scholarship

2015 First place in Summer Scholarship Research Project

2015 Snowvision State of New York Scholarship

2018 HOPE Selwyn Foundation Scholarship in Ageing Research

2018 NZAO HC Russell Memorial Postgraduate Scholarship

Selected publications and creative works (Research Outputs)

Pan, X., Lie, A. L., White, T. W., Donaldson, P. J., & Vaghefi, E. (2019). Development of an in vivo magnetic resonance imaging and computer modelling platform to investigate the physiological optics of the crystalline lens. Biomedical optics express, 10 (9), 4462-4478. 10.1364/BOE.10.004462
URL: http://hdl.handle.net/2292/48706
Other University of Auckland co-authors: Paul Donaldson, Ehsan Vaghefi, Wilson Pan
Gao, T. Y., Ledgeway, T., Lie, A. L., Anstice, N., Black, J., McGraw, P. V., & Thompson, B. (2018). Orientation Tuning and Contrast Dependence of Continuous Flash Suppression in Amblyopia and Normal Vision. Investigative ophthalmology & visual science, 59 (13), 5462-5472. 10.1167/iovs.18-23954
URL: http://hdl.handle.net/2292/46754
Other University of Auckland co-authors: Yitian Tina Gao, Joanna Black, Benjamin Thompson, Nicola Anstice
Lie, A. L., Pan, X., Donaldson, P. J., White, T. W., & Vaghefi, E. (2018). The lens paradox is due to an age-related shift in optical centre of the lens. Paper presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu, HI. 29 April - 3 May 2018. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. (pp. 2).
URL: http://hdl.handle.net/2292/45442
Other University of Auckland co-authors: Paul Donaldson, Ehsan Vaghefi
Nye-Wood, M. G., Lie, A. L., Donaldson, P. J., & Vaghefi, E. (2018). Physiological optics of the accommodating lens: a clinical observational study using MRI. Paper presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu, HI. 29 April - 3 May 2018. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. (pp. 2).
Other University of Auckland co-authors: Wilson Pan, Paul Donaldson, Ehsan Vaghefi
Pan, X., Lie, A. L., Donaldson, P., White, T., & Vaghefi, E. (15/12/2017). Investigating the alternations of lens physiological optics of nuclear cataracts using magnetic resonance imaging (MRI). Poster presented at The 5th International Conference on the Lens, Kailua Kona, Hawaii. Related URL.
Other University of Auckland co-authors: Wilson Pan, Paul Donaldson
Gao, T. Y., Ledgeway, T., Lie, A., Anstice, N., Black, J., McGraw, P., & Thompson, B. (2016). Continuous Flash Suppression in Amblyopia is Asymmetric and Non-selective for Stimulus Orientation. Paper presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Seattle, WA. 1 May - 5 May 2016. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. (pp. 3).
Other University of Auckland co-authors: Benjamin Thompson, Joanna Black, Yitian Tina Gao