Miss Alyssa Lesley Lie

BOptom (Hons) TPA

Biography

Alyssa is a therapeutically endorsed optometrist, having completed her Bachelors degree in Optometry (with Honours) at the University of Auckland in 2015. She worked as a general optometrist in a busy private practice in Northland and spent time at State University of New York's Optometry college as a visiting doctor. After practising for 2 years in community optometry, Alyssa returned to the University of Auckland in 2017 to pursue a PhD in Optometry under the supervision of Dr Ehsan Vaghefi and Professor Paul Donaldson.

Following the completion of her doctoral studies in 2021, Alyssa currently holds joint appointments as a lecturer at the School of Optometry and Vision Science and as a postdoctoral research fellow with the Molecular Vision Research Cluster at the Department of Physiology. She also continues to practice as an optometrist for glaucoma clinics in a private ophthalmology practice.

Research | Current

Alyssa's primary area of research involves utilising magnetic resonance imaging (MRI) techniques to investigate the physiology of the human crystalline lens, with the aim of determining whether changes at a cellular and molecular level can be used to predict the onset and/or progression of age-related lenticular pathologies such as presbyopia (loss of near vision) and cataract (loss of lens transparency).

Identifying early biomarkers for presbyopia and cataract would inform the development of novel therapeutic strategies to delay and/or prevent the visual impairment associated with these conditions, and ultimately alleviate the significant social and economic burden associated with the treatments available at present.

Teaching | Current

OPTOM 216: Introduction to Optometry

OPTOM 316: Optometry

OPTOM 353: Ocular Pathology

OPTOM 416: Clinical Optometry

OPTOM 442: Optometry for Special Populations

OPTOM 783: Research Project in Vision Science

Distinctions/Honours

2021 Association for Research in Vision and Ophthalmology Lens and Cataract Travel Grant

2019 Sir John Logan Campbell Medical Trust Award

2019 National Foundation for Eye Research Young Investigator Travel Award

2019 Faculty of Medical and Health Sciences Postgraduate Student Association Student Travel Award. 

2019 HOPE Selwyn Foundation Scholarship in Ageing Research

2018 New Zealand Association of Optometrists HC Russell Memorial Postgraduate Scholarship

2018 HOPE Selwyn Foundation Scholarship in Ageing Research

2015 Snowvision State of New York Scholarship

2015 First place in Summer Scholarship Research Project

2014 New Zealand Association of Optometrists Paul Dunlop Memorial Research Scholarship

Committees/Professional groups/Services

New Zealand Association of Optometrists (NZAO)

Selected publications and creative works (Research Outputs)

As of 29 October 2020 there will be no automatic updating of 'selected publications and creative works' from Research Outputs. Please continue to keep your Research Outputs profile up to date.
  • Lie, A. L., Pan, X., White, T. W., Donaldson, P. J., & Vaghefi, E. (2020). Using the Lens Paradox to Optimize an In Vivo MRI-Based Optical Model of the Aging HumanCrystalline Lens. TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 9 (8)10.1167/tvst.9.8.39
    Other University of Auckland co-authors: Ehsan Vaghefi, Wilson Pan, Paul Donaldson
  • Pan, X., Lie, A. L., White, T. W., Donaldson, P. J., & Vaghefi, E. (2019). Development of an in vivo magnetic resonance imaging and computer modelling platform to investigate the physiological optics of the crystalline lens. Biomedical optics express, 10 (9), 4462-4478. 10.1364/BOE.10.004462
    Other University of Auckland co-authors: Paul Donaldson, Ehsan Vaghefi, Wilson Pan
  • Gao, T. Y., Ledgeway, T., Lie, A. L., Anstice, N., Black, J., McGraw, P. V., & Thompson, B. (2018). Orientation Tuning and Contrast Dependence of Continuous Flash Suppression in Amblyopia and Normal Vision. Investigative ophthalmology & visual science, 59 (13), 5462-5472. 10.1167/iovs.18-23954
    Other University of Auckland co-authors: Tina Gao, Joanna Black, Benjamin Thompson, Nicola Anstice
  • Lie, A. L., Pan, X., Donaldson, P. J., White, T. W., & Vaghefi, E. (2018). The lens paradox is due to an age-related shift in optical centre of the lens. Paper presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu, HI. 29 April - 3 May 2018. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. (pp. 2).
    URL: http://hdl.handle.net/2292/45442
    Other University of Auckland co-authors: Paul Donaldson, Ehsan Vaghefi, Wilson Pan
  • Nye-Wood, M. G., Lie, A. L., Donaldson, P. J., & Vaghefi, E. (2018). Physiological optics of the accommodating lens: a clinical observational study using MRI. Paper presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu, HI. 29 April - 3 May 2018. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. (pp. 2).
    Other University of Auckland co-authors: Wilson Pan, Paul Donaldson, Ehsan Vaghefi
  • Pan, X., Lie, A. L., Donaldson, P., White, T., & Vaghefi, E. (15/12/2017). Investigating the alternations of lens physiological optics of nuclear cataracts using magnetic resonance imaging (MRI). Poster presented at The 5th International Conference on the Lens, Kailua Kona, Hawaii. Related URL.
    Other University of Auckland co-authors: Wilson Pan, Paul Donaldson
  • Gao, T. Y., Ledgeway, T., Lie, A., Anstice, N., Black, J., McGraw, P., & Thompson, B. (2016). Continuous Flash Suppression in Amblyopia is Asymmetric and Non-selective for Stimulus Orientation. Paper presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Seattle, WA. 1 May - 5 May 2016. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. (pp. 3).
    Other University of Auckland co-authors: Benjamin Thompson, Joanna Black, Tina Gao

Contact details

Primary office location

M&HS BUILDING 503 - Bldg 503
Level 3, Room 351A
85 PARK RD
NZL
AUCKLAND 1023
New Zealand