Dr Anassuya Ramachandran

PhD (University of Auckland)

Biography

2007 PhD, University of Auckland, New Zealand

2008-2011 Nuffield Medical Research Fellow, University of Oxford, Oxford, UK

2011-2019 Postdoctoral Research Fellow, Francis Crick Institute, London, UK

Areas of expertise

CRISPR/Cas9

TGF-beta signalling

BMP signalling

Molecular biology

Cancer biology

Selected publications and creative works (Research Outputs)

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  • Ramachandran, A., Vizán P, Das, D., Chakravarty, P., Vogt, J., Rogers, K. W., ... Hill, C. S. (2018). TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition. eLife, 7.10.7554/elife.31756
  • Del Pozo Martin, Y., Park, D., Ramachandran, A., Ombrato, L., Calvo, F., Chakravarty, P., ... Sahai, E. (2015). Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization. Cell reports, 13 (11), 2456-2469. 10.1016/j.celrep.2015.11.025
  • Blick, C., Ramachandran, A., McCormick, R., Wigfield, S., Cranston, D., Catto, J., & Harris, A. L. (2015). Identification of a hypoxia-regulated miRNA signature in bladder cancer and a role for miR-145 in hypoxia-dependent apoptosis. British journal of cancer, 113 (4), 634-644. 10.1038/bjc.2015.203
  • Blick, C., Ramachandran, A., Wigfield, S., McCormick, R., Jubb, A., Buffa, F. M., ... Catto, J. (2013). Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer. British journal of cancer, 109 (1), 50-59. 10.1038/bjc.2013.240
  • Ramachandran, A., Betts, G., Bhana, S., Helme, G., Blick, C., Moller-Levet, C., ... Miller, C. J. (2013). An in vivo hypoxia metagene identifies the novel hypoxia inducible factor target gene SLCO1B3. European journal of cancer (Oxford, England : 1990), 49 (7), 1741-1751. 10.1016/j.ejca.2012.12.003
  • Grönroos E, Kingston, I. J., Ramachandran, A., Randall, R. A., Vizán P, & Hill, C. S. (2012). Transforming growth factor β inhibits bone morphogenetic protein-induced transcription through novel phosphorylated Smad1/5-Smad3 complexes. Molecular and cellular biology, 32 (14), 2904-2916. 10.1128/mcb.00231-12
  • Favaro, E., Ramachandran, A., McCormick, R., Gee, H., Blancher, C., Crosby, M., ... Li, J.-L. (2010). MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. PloS one, 5 (4)10.1371/journal.pone.0010345
  • Ramachandran, A., Marshall, E. S., Love, D. R., Baguley, B. C., & Shelling, A. N. (2009). Activin is a potent growth suppressor of epithelial ovarian cancer cells. CANCER LETTERS, 285 (2), 157-165. 10.1016/j.canlet.2009.05.010
    URL: http://hdl.handle.net/2292/15884
    Other University of Auckland co-authors: Don Love, Andrew Shelling

Contact details

Primary office location

M&HS BUILDING 501 - Bldg 501
Level 2, Room 210
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand