Associate Professor Bernard de Bono


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Principal Investigator


Bernard de Bono, MD PhD, leads on the development of semantic interoperability infrastructure and standards for biomedical resources. In particular, he is developing the requisite computational infrastructure for the ontology-based annotation, sharing and inferencing of physiology-related semantic metadata to bridge resources generated by the Innovative Medicines Initiative and Virtual Physiological Human communities.

In addition, de Bono has developed the ApiNATOMY approach to ontology visualisation in support of more effective knowledge management by the physiology and pharmaceutical research communities. de Bono holds Principal Investigator positions at the Auckland Bioengineering Institute and University College London.

Areas of expertise

  • Bioinformatics
  • Computational Biology
  • Physiology

Selected publications and creative works (Research Outputs)

As of 29 October 2020 there will be no automatic updating of 'selected publications and creative works' from Research Outputs. Please continue to keep your Research Outputs profile up to date.
  • de Bono, B., Safaei, S., Grenon, P., & Hunter, P. (2018). Meeting the multiscale challenge: Representing physiology processes over ApiNATOMY circuits using bond graphs. Interface Focus, 8 (1)10.1098/rsfs.2017.0026
    Other University of Auckland co-authors: Peter Hunter, Soroush Safaei
  • Wu, H., Oellrich, A., Girges, C., de Bono, B., Hubbard, T. J., & Dobson, R. J. (2017). Automated PDF highlighting to support faster curation of literature for Parkinson's and Alzheimer's disease. Database: The Journal of Biological Databases and Curation, 2017 (1), 1-14. 10.1093/database/bax027
  • Safaei, S., Bradley, C. P., Suresh, V., Mithraratne, K., Muller, A., Ho, H., ... Chase, J. G. (2016). Roadmap for cardiovascular circulation model. Journal of Physiology, 594 (23), 6909-6928. 10.1113/jp272660
    Other University of Auckland co-authors: Peter Hunter, Harvey Ho, Soroush Safaei, Christopher Bradley, Kumar Mithraratne, Vinod Suresh
  • Graf, N., de Bono, B., Bucur, A., Buechler, P., Byrne, H., Dong, F., ... Kolokotroni, E. (2016). A Multiscale Hypermodel to Predict the Nephroblastoma Response to Preoperative Chemotherapy. PEDIATRIC BLOOD & CANCER. (pp. 1).
  • Thomas, S., Wolstencroft, K., de Bono, B., & Hunter, P. J. (2016). A physiome interoperability roadmap for personalized drug development. Interface Focus, 6 (2)10.1098/rsfs.2015.0094
    Other University of Auckland co-authors: Peter Hunter
  • de Bono, B., Helvensteijn, M., Kokash, N., Martorelli, I., Sarwar, D., Islam, S., ... Hunter, P. (2016). Requirements for the formal representation of pathophysiology mechanisms by clinicians. Interface Focus, 6 (2)10.1098/rsfs.2015.0099
    Other University of Auckland co-authors: Peter Hunter
  • Nickerson, D., Atalag, K., de Bono, B., Geiger, J., Goble, C., Hollmann, S., ... Stanford, N. J. (2016). The human physiome: How standards, software and innovative service infrastructures are providing the building blocks to make it achievable. Interface Focus, 6 (2)10.1098/rsfs.2015.0103
    Other University of Auckland co-authors: David Nickerson, Peter Hunter, Koray Atalag
  • Nickerson, D. P., Atalag, K., de Bono, B., & Hunter, P. (2016). The Physiome Project, openEHR Archetypes and the Digital Patient. In C. D. Combs, J. A. Sokolowski, C. M. Banks (Eds.) The Digital Patient Advancing Healthcare, Research, and Education (pp. 101-126). Hoboken, New Jersey, United States: John Wiley & Sons.
    Other University of Auckland co-authors: Koray Atalag, David Nickerson, Peter Hunter

Contact details

Alternative contact

University College, London.

Primary office location

Level 6, Room 639
New Zealand

Web links