Miss Brooke Carol Wilson
MSc in Biological Sciences (First Class Honours)
Currently a doctoral candidate at the Liggins Institute undertaking research into the human gut microbiome. Before returning to New Zealand to undertake my doctoral studies I worked for several years as a research assistant in the Department of Medical and Molecular Genetics at King's College London (Guy's Hospital Campus). During my time there I was involved in using CRISPR/Cas9 technology to investigate the function of an essential transcription factor. Prior to moving overseas, I had completed two undergraduate work placements and my MSc research at AgResearch, specifically focused on reproductive technologies and embryonic stem cell research.
Research | Current
PhD topic: Alteration of the Gut Microbiome through Microbiota Transplantation
This research looks at two microbiota transplantation approaches:
- Fecal Microbiota Transplantation (FMT) involving the transfer of a healthy individual's stool to an indivudal with gut dysbiosis. FMT is currently being trialed as a treatment for gut dysbiosis associated conditions such as IBD and obesity.
- Vaginal Microbiota Transplantation (VMT), also known as vaginal seeding, which is aimed at exposing caesarean section delivered babies to their mother's vaginal microbiota immediately after birth - a step that may well be required for appropriate development of the baby's immune system
Main Supervisor: A/Prof. Justin O'Sullivan
Co-Supervisors: Prof. Wayne Cutfield & Dr. Tommi Vatanen
Selected publications and creative works (Research Outputs)
- Wilson, B. C., Vatanen, T., Cutfield, W. S., & O'Sullivan JM (2019). The Super-Donor Phenomenon in Fecal Microbiota Transplantation. Frontiers in cellular and infection microbiology, 910.3389/fcimb.2019.00002
Other University of Auckland co-authors: Wayne Cutfield, Tommi Vatanen, Justin O'Sullivan