Dr Brya Matthews

BSc (Hons), PhD

Senior Research Fellow

In: Molecular Medicine and Pathology » Medical Science » Faculty of Medical and Health Sciences

Biography

Brya Matthews completed her PhD at the University of Auckland in 2009, and after a short time doing postdoctoral work in Auckland, completed further postdoctoral research at the University of Connecticut School of Dental Medicine in Connecticut, USA. She was later promoted to Instructor then Assistant Professor before returning to New Zealand in 2017 to take up a Sir Charles Hercus Fellowship in the Department of Molecular Medicine.

Research | Current

I am interested in adult stem cells involved in bone healing. My research focuses on identifying stem cell populations in the periosteum, the tissue that surrounds the outside of the bone, and examining how these cells respond to injury.

Selected publications and creative works (Research Outputs)

Vidovic Zdrilic, I., de Azevedo Queiroz, I. O., Matthews, B. G., Gomes-Filho, J. E., Mina, M., & Kalajzic, I. (2017). Mineral trioxide aggregate improves healing response of periodontal tissue to injury in mice. Journal of periodontal research, 52 (6), 1058-1067. 10.1111/jre.12478
Matthews, B. G., Roeder, E., Wang, X., Aguila, H. L., Lee, S.-K., Grcevic, D., & Kalajzic, I. (2017). Splenomegaly, myeloid lineage expansion and increased osteoclastogenesis in osteogenesis imperfecta murine. Bone, 103, 1-11. 10.1016/j.bone.2017.06.004
Vidovic, I., Banerjee, A., Fatahi, R., Matthews, B., Dyment, N., Kalajzic, I., & Mina, M. (2017). αSMA-expressing perivascular cells represent dental pulp progenitors In vivo. Journal of Dental Research, 96 (3), 323-330. 10.1177/0022034516678208
Matic, I., Matthews, B. G., Wang, X., Dyment, N. A., Worthley, D. L., Rowe, D. W., ... Kalajzic, I. (2016). Quiescent bone lining cells are a major source of osteoblasts during adulthood. Stem Cells, 34 (12), 2930-2942. 10.1002/stem.2474
Joo Kim, J., Musson, D. S., Matthews, B. G., Cornish, J., Anderson, I. A., & Shim, V. B. (2016). Applying physiologically relevant strains to tenocytes in an in vitro cell device induces in vivo like behaviors. Journal of Biomechanical Engineering, 138 (12)10.1115/1.4034031
URL: http://hdl.handle.net/2292/31533
Other University of Auckland co-authors: Vickie Shim, Jillian Cornish, Iain Anderson, David Musson
Roeder, E., Matthews, B. G., & Kalajzic, I. (2016). Visual reporters for study of the osteoblast lineage. Bone, 92, 189-195. 10.1016/j.bone.2016.09.004
Matthews, B., Roguljic, H., Franceschetti, T., Roeder, E., Matic, I., Vidovic, I., ... Kalajzic, I. (2016). Gene-expression analysis of cementoblasts and osteoblasts. Journal of Periodontal Research, 51 (3), 304-312. 10.1111/jre.12309
Matthews, B. G., Torreggiani, E., Roeder, E., Matic, I., Grcevic, D., & Kalajzic, I. (2016). Osteogenic potential of alpha smooth muscle actin expressing muscle resident progenitor cells. Bone, 84, 69-77. 10.1016/j.bone.2015.12.010