Dr Brya Matthews
BSc (Hons), PhD
Brya Matthews completed her PhD at the University of Auckland, and after a short time doing postdoctoral work in Auckland, completed further postdoctoral research at the University of Connecticut School of Dental Medicine in Connecticut, USA. She was later promoted to Instructor then Assistant Professor before returning to New Zealand in 2017 to take up a Sir Charles Hercus Fellowship in the Department of Molecular Medicine.
Research | Current
I am interested in adult stem cells involved in bone healing. My research focuses on identifying stem cell populations in the periosteum, the tissue that surrounds the outside of the bone, and examining how these cells respond to injury. I am also interested in other aspects of bone healing, including the role of innervation in regeneration, as well as understanding the bone phenotype in animal models of disrupted metabolism.
Teaching | Current
MEDSCI315 Nutrigenomics - bone biology and nutrition
MEDSCI740 Stem cell biology and transgenesis
MEDSCI312 Endocrinology - guest lecture on metabolic bone disease
I am recruiting all types of graduate students. Please see Find-a-thesis for projects available. I have a doctoral scholarship available for qualified students.
Areas of expertise
Mesenchymal/skeletal stem cells
Selected publications and creative works (Research Outputs)
- Wee, N. K. Y., Sinder, B. P., Novak, S., Wang, X., Stoddard, C., Matthews, B. G., & Kalajzic, I. (2019). Skeletal phenotype of the neuropeptide Y knockout mouse. Neuropeptides, 73, 78-88. 10.1016/j.npep.2018.11.009
- Vidovic Zdrilic, I., de Azevedo Queiroz, I. O., Matthews, B. G., Gomes-Filho, J. E., Mina, M., & Kalajzic, I. (2017). Mineral trioxide aggregate improves healing response of periodontal tissue to injury in mice. Journal of periodontal research, 52 (6), 1058-1067. 10.1111/jre.12478
- Matthews, B. G., Roeder, E., Wang, X., Aguila, H. L., Lee, S.-K., Grcevic, D., & Kalajzic, I. (2017). Splenomegaly, myeloid lineage expansion and increased osteoclastogenesis in osteogenesis imperfecta murine. Bone, 103, 1-11. 10.1016/j.bone.2017.06.004
- Vidovic, I., Banerjee, A., Fatahi, R., Matthews, B., Dyment, N., Kalajzic, I., & Mina, M. (2017). αSMA-expressing perivascular cells represent dental pulp progenitors In vivo. Journal of Dental Research, 96 (3), 323-330. 10.1177/0022034516678208
- Matic, I., Matthews, B. G., Wang, X., Dyment, N. A., Worthley, D. L., Rowe, D. W., ... Kalajzic, I. (2016). Quiescent bone lining cells are a major source of osteoblasts during adulthood. Stem Cells, 34 (12), 2930-2942. 10.1002/stem.2474
- Joo Kim, J., Musson, D. S., Matthews, B. G., Cornish, J., Anderson, I. A., & Shim, V. B. (2016). Applying physiologically relevant strains to tenocytes in an in vitro cell device induces in vivo like behaviors. Journal of Biomechanical Engineering, 138 (12)10.1115/1.4034031
Other University of Auckland co-authors: Vickie Shim, Jillian Cornish, Iain Anderson, David Musson
- Roeder, E., Matthews, B. G., & Kalajzic, I. (2016). Visual reporters for study of the osteoblast lineage. Bone, 92, 189-195. 10.1016/j.bone.2016.09.004
- Matthews, B., Roguljic, H., Franceschetti, T., Roeder, E., Matic, I., Vidovic, I., ... Kalajzic, I. (2016). Gene-expression analysis of cementoblasts and osteoblasts. Journal of Periodontal Research, 51 (3), 304-312. 10.1111/jre.12309