Dr Carol Ann Greene

PhD Ophthalmology, MSc Applied Genetics, BSc Microbiology

Research | Current

My research focus is the cornea. Specifically my research is directed at understanding the function of the various layers of the cornea with the aim of developing new strategies for corneal regeneration. Projects I am currently involved in are:

1) Developing a novel therapy for strengthening and regenerating the cornea. This is an extension of my previous research on corneal cell pluripotency and cell reprogramming.

2) Assessing the epithelial basement membrane in healthy and diseased corneas with the aim of dissecting the cause of aberrant basement membranes associated with corneal pathology.

3) The development and testing of a 3D printed bandage for corneal wound healing

Distinctions/Honours

2018, Invited speaker at the Ideas to life conference: Innovations for Healthy Living at Hangzhou, China.

2016, Maurice Wilkins Centre Entrepreneurship Workshop Pitch presentation prize

2016, Travel grant awarded by the International Society for Eye Research (ISER) to attend the annual meeting at Tokyo (September 25-29th 2016)

2013, Chiasma Award for the best bioscience idea in the Spark Ideas Challenge

2013, Travel grant awarded by the Association for Research in Vision and Ophthalmology to attend and present at their Annual meeting (March 2013)

2011, University of Auckland Doctoral Scholarship

Responsibilities

2016-2017, Secretary and head of Communications, Faculty Postdoctoral Society, University of Auckland

2013, Chiasma Award for the best bioscience idea in the Spark Ideas Challenge

2013- 2014, President of the Faculty of Medical and Health Sciences Post Graduate Students’ Association

2012, Member of the University Post Graduate Students’ Association, University of Auckland

 

Areas of expertise

Cornea

Cell reprogramming

Keratoconus

Committees/Professional groups/Services

2016- Present Member of the International Society for Eye Research

2011- Present, Association for Research in Vision and Ophthalmology

Selected publications and creative works (Research Outputs)

  • Greene, C. A., Misra, S. L., Lee, H., McKelvie, J., Kapadia, K., McFarlane, R., ... Sherwin, T. (2018). The Sheep Cornea: Structural and Clinical Characteristics. Current eye research, 43 (12), 1432-1438. 10.1080/02713683.2018.1510970
    Other University of Auckland co-authors: Charles McGhee, Stuti Misra, Trevor Sherwin, Colin Green
  • Zidan, G., Rupenthal, I. D., Greene, C., & Seyfoddin, A. (2018). Medicated ocular bandages and corneal health: Potential excipients and active pharmaceutical ingredients. Pharmaceutical Development and Technology, 23 (3), 255-260. 10.1080/10837450.2017.1377232
    Other University of Auckland co-authors: Ilva Rupenthal
  • Ziaei, M., Greene, C., & Green, C. R. (2018). Wound healing in the eye: Therapeutic prospects. Advanced drug delivery reviews, 126, 162-176. 10.1016/j.addr.2018.01.006
    Other University of Auckland co-authors: Colin Green
  • Greene, C. A., Kuo, C., & Sherwin, T. (2017). Aberrant Patterns of Key Epithelial Basement Membrane Components in Keratoconus. Cornea, 36 (12), 1549-1555. 10.1097/ico.0000000000001393
    Other University of Auckland co-authors: Trevor Sherwin
  • Greene, C. A., Green, C. R., Dickinson, M. E., Johnson, V., & Sherwin, T. (2016). Keratocytes are induced to produce collagen type II: A new strategy for in vivo corneal matrix regeneration. Experimental Cell Research, 347 (1), 241-249. 10.1016/j.yexcr.2016.08.010
    URL: http://hdl.handle.net/2292/30604
    Other University of Auckland co-authors: Trevor Sherwin, Colin Green
  • Greene, C. A., Johnson, V., Dickinson, M., Green, C. R., & Sherwin, T. (2016). Keratocyte plasticity and the potential for harnessing it for regenerating the stroma.. Paper presented at ISER 2016: XXII Biennial Meeting of the International Society for Eye Research, Tokyo, Japan. 25 September - 29 September 2016. Related URL.
    Other University of Auckland co-authors: Colin Green, Trevor Sherwin
  • Greene, C. A., Green, C. R., & Sherwin, T. (2015). Transdifferentiation of chondrocytes into neuron-like cells induced by neuronal lineage specifying growth factors. Cell Biology International, 39 (2), 185-191. 10.1002/cbin.10358
    URL: http://hdl.handle.net/2292/24700
    Other University of Auckland co-authors: Trevor Sherwin, Colin Green
  • Greene, C. A. (2015). Growth Factor Mediated Reprogramming of Adult Corneal Keratocytes as an Exemplar of In Vivo Tissue Engineering The University of Auckland. ResearchSpace@Auckland.
    URL: http://hdl.handle.net/2292/27090

Contact details

Primary office location

M&HS BUILDING 504 - Bldg 504
Level 4, Room 435
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand