Dr Christian K Miller

Selected publications and creative works (Research Outputs)

  • Spicer, J. A., Miller, C. K., O'Connor PD, Jose, J., Huttunen, K. M., Jaiswal, J. K., ... Trapani, J. A. (2017). Substituted arylsulphonamides as inhibitors of perforin-mediated lysis. European journal of medicinal chemistry, 137, 139-155. 10.1016/j.ejmech.2017.05.048
    Other University of Auckland co-authors: Julie Spicer, Jiney Jose, Bill Denny, Jagdish Jaiswal
  • Spicer, J. A., Miller, C. K., O'Connor PD, Jose, J., Huttunen, K. M., Jaiswal, J. K., ... Trapani, J. A. (2017). Benzenesulphonamide inhibitors of the cytolytic protein perforin. Bioorganic & medicinal chemistry letters, 27 (4), 1050-1054. 10.1016/j.bmcl.2016.12.057
    Other University of Auckland co-authors: Bill Denny, Julie Spicer, Jiney Jose, Jagdish Jaiswal
  • Giddens, A. C., Lee, H. H., Lu, G.-L., Miller, C. K., Guo, J., Lewis Phillips, G. D., ... Tercel, M. (2016). Analogues of DNA minor groove cross-linking agents incorporating aminoCBI, an amino derivative of the duocarmycins: Synthesis, cytotoxicity, and potential as payloads for antibody-drug conjugates. Bioorganic & medicinal chemistry, 24 (22), 6075-6081. 10.1016/j.bmc.2016.09.068
    Other University of Auckland co-authors: Moana Tercel, Leon Lu, Ho Lee, Anna Giddens
  • Miller, C. K., Huttunen, K. M., Denny, W. A., Jaiswal, J. K., Ciccone, A., Browne, K. A., ... Spicer, J. A. (2016). Diarylthiophenes as inhibitors of the pore-forming protein perforin. Bioorganic and Medicinal Chemistry Letters, 26 (2), 355-360. 10.1016/j.bmcl.2015.12.003
    URL: http://hdl.handle.net/2292/28137
    Other University of Auckland co-authors: Bill Denny, Julie Spicer, Jagdish Jaiswal
  • Spicer, J. A., Miller, C., O'Connor P, Jose, J., Jaiswal, J., Jamieson, S. M. F., ... Akhlaghi, H. (2015). Inhibitors of the pore-forming protein perforin as potential immunosuppressive agents. Paper presented at Pacifichem, Honolulu, Hawaii, USA. 15 December - 20 December 2015.
    Other University of Auckland co-authors: Jiney Jose, Jagdish Jaiswal, Stephen Jamieson, Bill Denny
  • Flygare, J. A., Pillow, T. H., Safina, B., Verma, V., Wei, B. Q., Denny, W., ... Miller, C.. 1-(Chloromethyl)-2,3-dihydro-1H-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment. WO 2015/023355 A1 Related URL.
    URL: http://hdl.handle.net/2292/27904
    Other University of Auckland co-authors: Gordon Rewcastle, Bill Denny, Anna Giddens, Ho Lee, Leon Lu, Moana Tercel
  • Spicer, J. A., Denny, W. A., Miller, C. K., O'Connor PD, Huttunen, K., Trapani, J. A., ... Alexander, K.. Perforin inhibiting benzenesulfonamide compounds, preparation and uses thereof. US 61/691652 Related URL.
  • Spicer, J. A., Lena, G., Lyons, D. M., Huttunen, K. M., Miller, C. K., O'Connor PD, ... Denny, W. A. (2013). Exploration of a series of 5-arylidene-2-thioxoimidazolidin-4-ones as inhibitors of the cytolytic protein perforin. J Med Chem, 56 (23), 9542-9555. 10.1021/jm401604x
    Other University of Auckland co-authors: Nuala Helsby, Bill Denny, Julie Spicer, Stephen Jamieson, Matthew Bull