Dr Daniel Plimmer Furkert

PhD

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Senior Research Fellow

Biography

Dan gained his PhD in chemistry in 2003 (UoA), followed by NIH postdoctoral fellowships at Oregon State University (USA) working on natural product total synthesis, and then in the Dept of Pharmacy & Pharmacology at the University of Bath (UK) investigating novel opioid receptor ligands for treatment of drug abuse.

He returned to UoA in 2010 to take up his current position as team leader of Dist Prof Margaret Brimble's organicsynthesis labs.

Research | Current

Current research themes include organic synthesis directed towards natural products and drug discovery, development of improved chemical methods to access biologically relevant structures, and medicinal chemistry focused on TB, cancer and neuropharmacology.

Teaching | Current

Lectures in CHEM330, CHEM730 

Selected publications and creative works (Research Outputs)

  • Schumacher, C. E., Harris, P. W. R., Ding, X.-B., Krause, B., Wright, T. H., Cook, G. M., ... Brimble, M. A. (2017). Synthesis and biological evaluation of novel teixobactin analogues. Organic & biomolecular chemistry10.1039/c7ob02169k
    Other University of Auckland co-authors: Margaret Brimble, Paul Harris, Xiaobo Ding
  • Pantin, M., Hubert, J. G., Söhnel T, Brimble, M. A., & Furkert, D. P. (2017). Stereochemical Characterization of Polyketide Stereotriads Synthesized via Hydrogen-Mediated Asymmetric syn-Crotylation. The Journal of organic chemistry10.1021/acs.joc.7b01820
    Other University of Auckland co-authors: Margaret Brimble
  • Ding, X.-B., Furkert, D. P., & Brimble, M. A. (2017). General Synthesis of the Nitropyrrolin Family of Natural Products via Regioselective CO2-Mediated Alkyne Hydration. Organic letters10.1021/acs.orglett.7b02687
    Other University of Auckland co-authors: Margaret Brimble, Xiaobo Ding
  • Evans, G. L., Furkert, D. P., Abermil, N., Kundu, P., de Lange, K. M., Parker, E. J., ... Shaun Lott, J. (2017). Anthranilate phosphoribosyltransferase: Binding determinants for 5'-phospho-alpha-d-ribosyl-1'-pyrophosphate (PRPP) and the implications for inhibitor design. Biochimica et biophysica acta10.1016/j.bbapap.2017.08.018
    Other University of Auckland co-authors: Edward Baker, Shaun Lott
  • Choi, H., Shirley, H. J., Hume, P. A., Brimble, M. A., & Furkert, D. P. (2017). Unexpected Direct Synthesis of N -Vinyl Amides through Vinyl Azide-Enolate [3+2] Cycloaddition. Angewandte Chemie, 129 (26), 7528-7532. 10.1002/ange.201702727
    Other University of Auckland co-authors: Paul Hume
  • Wood, J. M., Furkert, D. P., & Brimble, M. A. (2017). Total Synthesis and Stereochemical Revision of the 2-Formylpyrrole Alkaloid Hemerocallisamine I. Journal of natural products, 80 (6), 1926-1929. 10.1021/acs.jnatprod.7b00314
    Other University of Auckland co-authors: Margaret Brimble
  • Choi, H., Shirley, H. J., Hume, P. A., Brimble, M. A., & Furkert, D. P. (2017). Unexpected Direct Synthesis of N-Vinyl Amides through Vinyl Azide-Enolate [3+2] Cycloaddition. Angewandte Chemie (International ed. in English)10.1002/anie.201702727
    Other University of Auckland co-authors: Paul Hume, Margaret Brimble
  • McPartland, J. M., MacDonald, C., Young, M., Grant, P. S., Furkert, D. P., & Glass, M. (2017). Affinity and Efficacy Studies of Tetrahydrocannabinolic Acid A at Cannabinoid Receptor Types One and Two. Cannabis and Cannabinoid Research, 2 (1), 87-95. 10.1089/can.2016.0032
    Other University of Auckland co-authors: Michelle Glass, Michelle Young

Contact details

Primary location

SCIENCE CENTRE - CHEMISTRY - Bldg 301
Level 7, Room 729A
23 SYMONDS ST
AUCKLAND 1010
New Zealand