Dr Darren Svirskis

BHB, BPharm, PhD

Senior Lecturer

In: Pharmacy » Faculty of Medical and Health Sciences

Research | Current

Research interests

Controlled Drug Delivery
Novel Drug Delivery Systems
Conducting Polymers
Polypyrrole
Implantable Drug Delivery

Postgraduate supervision

PhD Candidates - Principle supervisor

Dedeepya Uppalapati - Liquid crystalline templated conducting polymer structures

Prabhat Bhusal - Development of a recoverable controlled release polymeric implant for use following abdominal surgery

Zaid Aqrawe - Conducting polymer / neuronal communication

Saiful Azmi - Neuronal mimicry: Triggered glutamate release from a conducting polymer

PhD Candidates - Co-supervisor

Shawn (Guanyu) Chen - Development of a novel drug delivery system to enhance the oral bioavailability of Gemcitabine for the treatment of cancer (with Dr Jingyuan Wen)

Emma Kang - Cancer drug delivery systems and nano-carriers for drug targeting (with Dr Zimei Wu)

M. Naveed Yasin - Conducting polymer implant for on-demand ocular drug delivery (with Dr Ilva Rupenthal)

Marvin Tang - Co-delivery of gemcitabine and dCK DNA to overcome resistance to gemcitabine in pancreatic cancer (with Dr Zimei Wu)

Masters Candidates

Noor Tawfeek - Pharmacokinetic modelling of lidocaine and the development of a drug-eluting polymeric mesh to provide analgesia following hernia repair

Mahima Bansal - PEDOT membranes for tunable release of nicotine

Responsibilities

Undergraduate course coordination

Pharmacy 213 module leader for Gastrointestinal Tract

Postgraduate course coordination

Pharmacy 751: Pharmaceutical Techniques

Selected publications and creative works (Research Outputs)

Uppalapati, D., Boyd, B. J., Garg, S., Travas-Sejdic, J., & Svirskis, D. (2016). Conducting polymers with defined micro- or nanostructures for drug delivery. Biomaterials, 111, 149-162. 10.1016/j.biomaterials.2016.09.021
Other University of Auckland co-authors: Jadranka Travas-Sejdic
Ramtin, A., Seyfoddin, A., Coutinho, F. P., Waterhouse, G. I. N., Rupenthal, I. D., & Svirskis, D. (2016). Cytotoxicity considerations and electrically tunable release of dexamethasone from polypyrrole for the treatment of back-of-the-eye conditions. Drug delivery and translational research, 6 (6), 793-799. 10.1007/s13346-016-0284-0
Other University of Auckland co-authors: Geoffrey Waterhouse, Ilva Rupenthal
Bhusal, P., Harrison, J., Sharma, M., Jones, D. S., Hill, A. G., & Svirskis, D. (2016). Controlled release drug delivery systems to improve post-operative pharmacotherapy. Drug delivery and translational research, 6 (5), 441-451. 10.1007/s13346-016-0305-z
URL: http://hdl.handle.net/2292/31111
Other University of Auckland co-authors: Andrew Hill, Jeff Harrison, Manisha Sharma, Prabhat Bhusal
Aqrawe, Z., Montgomery, J., Travas-Sejdic, J., & Svirskis, D. (2016). Conducting Polymers as Electrode Coatings for Neuronal Multi-electrode Arrays. Trends in Biotechnology10.1016/j.tibtech.2016.06.007
Other University of Auckland co-authors: Jadranka Travas-Sejdic
Svirskis, D., Chandramouli, K., Bhusal, P., Wu, Z., Alphonso, J., Chow, J., ... Stowers, R. (2016). Injectable thermosensitive gelling delivery system for the sustained release of lidocaine. Therapeutic delivery, 7 (6), 359-368. 10.4155/tde-2016-0014
Other University of Auckland co-authors: Zimei Wu, Simon Young, Prabhat Bhusal, Manisha Sharma, Jacob Munro, Andrew Hill
Seyfoddin, A., Chan, A., Chen, W.-T., Rupenthal, I. D., Waterhouse, G. I. N., & Svirskis, D. (2015). Electro-responsive macroporous polypyrrole scaffolds for triggered dexamethasone delivery. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 94, 419-426. 10.1016/j.ejpb.2015.06.018
Other University of Auckland co-authors: Geoffrey Waterhouse, Ilva Rupenthal, Wan-Ting Chen
Yasin, M. N., Svirskis, D., Seyfoddin, A., & Rupenthal, I. D. (2014). Implants for drug delivery to the posterior segment of the eye: a focus on stimuli-responsive and tunable release systems. Journal of controlled release : official journal of the Controlled Release Society, 196, 208-221. 10.1016/j.jconrel.2014.09.030
Other University of Auckland co-authors: Ilva Rupenthal
Falconer, J. R., Wu, Z., Lau, H., Suen, J., Wang, L., Pottinger, S., ... Gargiulo, D. A. (2014). An Investigation into the Stability and Sterility of Citric Acid Solutions Used for Cough Reflex Testing. Dysphagia, 29 (5), 622-628. 10.1007/s00455-014-9558-1
URL: http://hdl.handle.net/2292/23162
Other University of Auckland co-authors: Zimei Wu, Derryn Gargiulo, Simon Swift