Dr Darren Svirskis

BHB, BPharm, PhD

Research | Current

Research interests

  • Controlled Drug Delivery
  • Novel Drug Delivery Systems
  • Conducting Polymers
  • Implantable Drug Delivery
  • Microelectrode Arrays
  • Brain:Machine Interface

Postgraduate supervision

Current PhD Candidates - Principle supervisor

Saiful Azmi - Neuronal mimicry: Triggered glutamate release from a conducting polymer

Mahima Bansal - A glutamate delivery system for neural stimulation

Anusha Dravid - Delivering nerve growth factor to promote outgrowth in lower motor neurons (with Simon O'Carroll) 

PhD Candidates - Co-supervisor

Marvin Tang - Co-delivery of gemcitabine and dCK DNA to overcome resistance to gemcitabine in pancreatic cancer (with A/Prof Zimei Wu)

Wiremu - Perioperative local anaesthetic (With Professor Andrew Hill)

Joy - Development of a novel drug delivery system for targeted brain delivery in neurodegenerative diseases (with A/Prof Zimei Wu)

Qing Xu - Pressure sensing PEDOT to improve ocular health (with Dr Duleepa Thrimawithana)

Current Masters Candidates

Zhumin (Nicola) Wei - Effect of drug molecular weight and charge on permeation through free standing PEDOT membranes

Nancy Bala - Towards biorelevant media: The influence of surface tension on drug release (with Dr Sara Hanning)

Completed PhDs (primary supervisor)

Dr Prabhat Bhusal - Development of a recoverable controlled release polymeric implant for use following abdominal surgery

Dr Dedeepya Uppalapati - Liquid crystalline templated conducting polymer structures

Dr Zaid Aqrawe - Conducting polymer / neuronal communication

Completed PhDs (co-supervisor)

Dr Travis Badenhorst - Dermal and cellular delivery of an endogenous peptide (with Dr Zimei Wu)

Dr Shawn (Guanyu) Chen - Development of a novel drug delivery system to enhance the oral bioavailability of Gemcitabine for the treatment of cancer (with Dr Jingyuan Wen)

Dr Emma Kang - Cancer drug delivery systems and nano-carriers for drug targeting (with Dr Zimei Wu)

Dr M. Naveed Yasin - Conducting polymer implant for on-demand ocular drug delivery (with Dr Ilva Rupenthal)


Undergraduate course coordination

Pharmacy 213 module leader for Gastrointestinal Tract

Pharmacy 412 module leader for Integrated Therapeutics

Postgraduate course coordination

Pharmacy 751: Pharmaceutical Techniques

Selected publications and creative works (Research Outputs)

  • Sharma, M., Chandramouli, K., Curley, L., Pontre, B., Reilly, K., Munro, J., ... Svirskis, D. (2018). In vitro and ex vivo characterisation of an in situ gelling formulation for sustained lidocaine release with potential use following knee arthroplasty. Drug delivery and translational research, 8 (3), 820-829. 10.1007/s13346-018-0492-x
    Other University of Auckland co-authors: Simon Young, Manisha Sharma, Keryn Reilly, Andrew Hill
  • Yasin, M. N., Brooke, R. K., Rudd, S., Chan, A., Chen, W.-T., Waterhouse, G. I. N., ... Svirskis, D. (2018). 3-Dimensionally ordered macroporous PEDOT ion-exchange resins prepared by vapor phase polymerization for triggered drug delivery: Fabrication and characterization. ELECTROCHIMICA ACTA, 269, 560-570. 10.1016/j.electacta.2018.02.162
    Other University of Auckland co-authors: Wan-Ting Chen, Geoffrey Waterhouse, Ilva Rupenthal, Andrew Chan
  • Bansal, M., Sharma, M., Bullen, C., & Svirskis, D. (2018). Free standing PEDOT films prepared by vapour phase polymerisation as electrically tuneable barriers to drug permeability. Materials science & engineering. C, Materials for biological applications, 84, 248-253. 10.1016/j.msec.2017.12.002
    Other University of Auckland co-authors: Manisha Sharma, Chris Bullen, Mahima Bansal
  • Aqrawe, Z., Montgomery, J., Travas-Sejdic, J., & Svirskis, D. (2017). Conducting polymers for neuronal microelectrode array recording and stimulation. Sensors and Actuators B: Chemical10.1016/j.snb.2017.11.023
    Other University of Auckland co-authors: Jadranka Travas-Sejdic, Zaid Aqrawe
  • Aqrawe, Z., Montgomery, J., Travas-Sejdic, J., & Svirskis, D. (2017). Conducting polymers as electrode coatings for neuronal multi-electrode arrays. Trends in Biotechnology, 35 (2), 93-95. 10.1016/j.tibtech.2016.06.007
    Other University of Auckland co-authors: Jadranka Travas-Sejdic, Johanna Montgomery, Zaid Aqrawe
  • Uppalapati, D., Boyd, B. J., Garg, S., Travas-Sejdic, J., & Svirskis, D. (2016). Conducting polymers with defined micro- or nanostructures for drug delivery. Biomaterials, 111, 149-162. 10.1016/j.biomaterials.2016.09.021
    Other University of Auckland co-authors: Jadranka Travas-Sejdic
  • Ramtin, A., Seyfoddin, A., Coutinho, F. P., Waterhouse, G. I. N., Rupenthal, I. D., & Svirskis, D. (2016). Cytotoxicity considerations and electrically tunable release of dexamethasone from polypyrrole for the treatment of back-of-the-eye conditions. Drug Delivery and Translational Research, 6 (6), 793-799. 10.1007/s13346-016-0284-0
    Other University of Auckland co-authors: Geoffrey Waterhouse, Ilva Rupenthal, Frazer Coutinho
  • Bhusal, P., Harrison, J., Sharma, M., Jones, D. S., Hill, A. G., & Svirskis, D. (2016). Controlled release drug delivery systems to improve post-operative pharmacotherapy. Drug Delivery and Translational Research, 6 (5), 441-451. 10.1007/s13346-016-0305-z
    URL: http://hdl.handle.net/2292/31111
    Other University of Auckland co-authors: Andrew Hill, Jeff Harrison, Manisha Sharma


Contact details

Primary office location

M&HS BUILDING 505 - Bldg 505
Level 3, Room 301
New Zealand

Web links