Dr Darren Svirskis

BHB, BPharm, PhD

Senior Lecturer

In: Pharmacy » Faculty of Medical and Health Sciences

Research | Current

Research interests

Controlled Drug Delivery
Novel Drug Delivery Systems
Conducting Polymers
Polypyrrole
Implantable Drug Delivery

Postgraduate supervision

PhD Candidates - Principle supervisor

Dedeepya Uppalapati - Liquid crystalline templated conducting polymer structures

Prabhat Bhusal - Development of a recoverable controlled release polymeric implant for use following abdominal surgery

Zaid Aqrawe - Conducting polymer / neuronal communication

Saiful Azmi - Neuronal mimicry: Triggered glutamate release from a conducting polymer

PhD Candidates - Co-supervisor

Shawn (Guanyu) Chen - Development of a novel drug delivery system to enhance the oral bioavailability of Gemcitabine for the treatment of cancer (with Dr Jingyuan Wen)

Emma Kang - Cancer drug delivery systems and nano-carriers for drug targeting (with Dr Zimei Wu)

M. Naveed Yasin - Conducting polymer implant for on-demand ocular drug delivery (with Dr Ilva Rupenthal)

Marvin Tang - Co-delivery of gemcitabine and dCK DNA to overcome resistance to gemcitabine in pancreatic cancer (with Dr Zimei Wu)

Masters Candidates

Noor Tawfeek - Pharmacokinetic modelling of lidocaine and the development of a drug-eluting polymeric mesh to provide analgesia following hernia repair

Mahima Bansal - PEDOT membranes for tunable release of nicotine

Responsibilities

Undergraduate course coordination

Pharmacy 213 module leader for Gastrointestinal Tract

Postgraduate course coordination

Pharmacy 751: Pharmaceutical Techniques

Selected publications and creative works (Research Outputs)

Yasin, M. N., Brooke, R. K., Rudd, S., Chan, A., Chen, W. T., Waterhouse, G. I. N., ... Svirskis, D. (2018). 3-Dimensionally ordered macroporous PEDOT ion-exchange resins prepared by vapor phase polymerization for triggered drug delivery: Fabrication and characterization. Electrochimica Acta, 269, 560-570. 10.1016/j.electacta.2018.02.162
Other University of Auckland co-authors: Wan-Ting Chen, Ilva Rupenthal
Bansal, M., Sharma, M., Bullen, C., & Svirskis, D. (2018). Free standing PEDOT films prepared by vapour phase polymerisation as electrically tuneable barriers to drug permeability. Materials science & engineering. C, Materials for biological applications, 84, 248-253. 10.1016/j.msec.2017.12.002
Other University of Auckland co-authors: Manisha Sharma, Chris Bullen, Mahima Bansal
Sharma, M., Chandramouli, K., Curley, L., Pontre, B., Reilly, K., Munro, J., ... Svirskis, D. (2018). In vitro and ex vivo characterisation of an in situ gelling formulation for sustained lidocaine release with potential use following knee arthroplasty. Drug delivery and translational research10.1007/s13346-018-0492-x
Other University of Auckland co-authors: Simon Young, Manisha Sharma, Keryn Reilly
Aqrawe, Z., Montgomery, J., Travas-Sejdic, J., & Svirskis, D. (2017). Conducting polymers for neuronal microelectrode array recording and stimulation. Sensors and Actuators B: Chemical10.1016/j.snb.2017.11.023
Other University of Auckland co-authors: Jadranka Travas-Sejdic, Zaid Aqrawe
Aqrawe, Z., Montgomery, J., Travas-Sejdic, J., & Svirskis, D. (2017). Conducting polymers as electrode coatings for neuronal multi-electrode arrays. Trends in Biotechnology, 35 (2), 93-95. 10.1016/j.tibtech.2016.06.007
Other University of Auckland co-authors: Jadranka Travas-Sejdic, Johanna Montgomery
Uppalapati, D., Boyd, B. J., Garg, S., Travas-Sejdic, J., & Svirskis, D. (2016). Conducting polymers with defined micro- or nanostructures for drug delivery. Biomaterials, 111, 149-162. 10.1016/j.biomaterials.2016.09.021
Other University of Auckland co-authors: Jadranka Travas-Sejdic
Ramtin, A., Seyfoddin, A., Coutinho, F. P., Waterhouse, G. I. N., Rupenthal, I. D., & Svirskis, D. (2016). Cytotoxicity considerations and electrically tunable release of dexamethasone from polypyrrole for the treatment of back-of-the-eye conditions. Drug delivery and translational research, 6 (6), 793-799. 10.1007/s13346-016-0284-0
Other University of Auckland co-authors: Geoffrey Waterhouse, Ilva Rupenthal, Frazer Coutinho
Bhusal, P., Harrison, J., Sharma, M., Jones, D. S., Hill, A. G., & Svirskis, D. (2016). Controlled release drug delivery systems to improve post-operative pharmacotherapy. Drug delivery and translational research, 6 (5), 441-451. 10.1007/s13346-016-0305-z
URL: http://hdl.handle.net/2292/31111
Other University of Auckland co-authors: Andrew Hill, Jeff Harrison, Manisha Sharma