Professor Eileen McLaughlin

PhD (Bristol), BSc Hons (Glasgow), Grad Cert Tertiary Education (Newcastle NSW)

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Head of School

Biography

The McLaughlin laboratory focusses on assisted reproduction, environmental toxicology and developmental biology. We have published over 130 research articles, and have obtained more than $32 million in competitive grant funding since 2001. Our work in parental and prenatal exposure to environmental toxicants has received significant public attention – most recently the studies of maternal smoking on male offspring reproductive health were profiled in TIME magazine.

Research | Current

Work in the McLaughlin laboratory is internationally recognised for expertise in assisted reproduction, environmental toxicology and developmental biology. 

Teaching | Current

BIOSCI 758: Development, Differentiation and Disease

BIOSCI 107: Biology for Biomedical Science: Cellular Processes and Development

Postgraduate supervision

Qualification

Name

Year Started

Thesis/Dissertation/

Project Topic/Title/University

Joint Supervisor

(if applicable)

Anticipated Year of Completion

Doctoral Candidates

Nicole Camlin

2013

Environmental consequences on oocyte competency

UoN

Janet Holt

Kate Redgrove

2016

 

Emma Lee Ford

2016

Primordial Follicle Activation in Premature Ovarian Failure: Understanding and Managing Fertility

UoN

Jessie Sutherland

2020

 

Bettina Mihalas

2015

Oxidation stress with age

UoN

Brett Nixon

Kate Redgrove

2019

 

Emily Bryan

2014

Chlamydial infection in males

QUT

Ken Beagley (QUT)

2017

Distinctions/Honours

2013

British Andrology Society Setchell Medallist

2011

Society for Reproductive Biology Fellow

2007

RCRH Award for Excellence in Reproductive Biology Research

1997

British Fertility Society FSA Award for Best Young Scientist

1997-00

The Wellcome Trust Fellowship in Reproductive Medicine

Responsibilities

Jan 2016 -           Australian Research Council CoE Grant Review Panel

Jan 2015 -          National Health & Medical Research Council Grant Review Panel

Areas of expertise

Reproductive and Developmental Biology

Committees/Professional groups/Services

Positions in Learned Societies

Society for the Study of Reproduction USA Programme Organising Committee (2015-present)

Society for Reproductive Biology  President (2012-2015) Chair New Investigator Award Committee / Programme Committee (2004-2007) Council member (2008-2015) Chair of Programme Organising Committee (2009-2012) World Congress Reproductive Biology Cairns (2011) POC member

Journal of Reproduction & Fertility  Director Council of Management (1997-00) Grants Committee (1998-00)

British Andrology Society Chairman (1997-00) Education Chairman (1995-7)

British Fertility Society Committee member (1997-00)

Association of Clinical Embryologists Executive committee (1999-01)

National Gamete Donation Trust Advisory Council Member (1998-00)

Society for Low Temperature Biology Meetings Secretary (1995-7) Conference Organiser - AGM Bristol 1998

Clinical Pathology Accreditation Ltd Specialist Advisory Council for Genetics (1997-00) Inspector (1997-00)

UKNEQAS for Andrology Steering Committee Member (1996-00)

Selected publications and creative works (Research Outputs)

  • Sutherland, J. M., Sobinoff, A. P., Fraser, B. A., Redgrove, K. A., Siddall, N. A., Koopman, P., ... McLaughlin, E. A. (2017). RNA binding protein Musashi-2 regulates PIWIL1 and TBX1 in mouse spermatogenesis. Journal of cellular physiology10.1002/jcp.26168
  • Hutcheon, K., McLaughlin, E. A., Stanger, S. J., Bernstein, I. R., Dun, M. D., Eamens, A. L., & Nixon, B. (2017). Analysis of the small non-protein-coding RNA profile of mouse spermatozoa reveals specific enrichment of piRNAs within mature spermatozoa. RNA biology10.1080/15476286.2017.1356569
  • Mihalas, B. P., De Iuliis, G. N., Redgrove, K. A., McLaughlin, E. A., & Nixon, B. (2017). The lipid peroxidation product 4-hydroxynonenal contributes to oxidative stress-mediated deterioration of the ageing oocyte. Scientific reports, 7 (1)10.1038/s41598-017-06372-z
  • Camlin, N. J., McLaughlin, E. A., & Holt, J. E. (2017). Motoring through: the role of kinesin superfamily proteins in female meiosis. Human reproduction update, 23 (4), 409-420. 10.1093/humupd/dmx010
  • Camlin, N. J., Jarnicki, A. G., Vanders, R. L., Walters, K. A., Hansbro, P. M., McLaughlin, E. A., & Holt, J. E. (2017). Grandmaternal smoke exposure reduces female fertility in a murine model, with great-grandmaternal smoke exposure unlikely to have an effect. Human reproduction (Oxford, England), 32 (6), 1270-1281. 10.1093/humrep/dex073
  • Bromfield, E. G., Mihalas, B. P., Dun, M. D., Aitken, R. J., McLaughlin, E. A., Walters, J. L. H., & Nixon, B. (2017). Inhibition of arachidonate 15-lipoxygenase prevents 4-hydroxynonenal-induced protein damage in male germ cells. Biology of Reproduction, 96 (3), 598-609. 10.1093/biolre/iox005
  • Bromfield, E. G., Aitken, R. J., McLaughlin, E. A., & Nixon, B. (2017). Proteolytic degradation of heat shock protein A2 occurs in response to oxidative stress in male germ cells of the mouse. Molecular Human Reproduction, 23 (2), 91-105. 10.1093/molehr/gaw074
    URL: http://hdl.handle.net/2292/33024
  • Camlin, N. J., McLaughlin, E. A., & Holt, J. E. (2017). The use of C57Bl/6 × CBA F1 hybrid cross as a model for human age-related oocyte aneuploidy. Molecular reproduction and development, 84 (1), 6-7. 10.1002/mrd.22766
    URL: http://hdl.handle.net/2292/33022

Identifiers

Contact details

Alternative contact

YY Tan y.tan@auckland.ac.nz ext84072

Primary location

THOMAS BUILDING - Bldg 110
Level 2, Room 256A
3 SYMONDS ST
AUCKLAND 1010
New Zealand

Social links

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