Dr Harvey Ho

BE SCUT, MSc PhD

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Research Fellow

Biography

Dr Ho graduated with a Bachelor of Engineering in Mechanical Engineering with Distinction from the South China University of Technology, a Master of Science with First Class Honours in Computer Science and a Doctor of Philosophy in Bioengineering from the University of Auckland.

His research interests include mathematical modelling for physiological flows, physiologically based pharmacokinetics (PBPK) modelling, 3D visualisation of bio-structures, medical image computing and surgical simulations. He is the first or corresponding author of ~40 peer-reviewed international journal papers/book chapters, including the top journals in his field (e.g., IEEE Transactions on Medical Imaging, IEEE Transactions on Biomedical Engineering).

Dr Ho is either the principal investigator or the key researcher in multiple multi-disciplinary projects. He was the manager of the Lamb Carcass Modelling project (2013-2015) commissioned by Silver Fern Farms, New Zealand's largest meat processing company. Currently he is leading a National Science Challenge project "Womb with a view" for which he and his collaborators are developing an anatomically accurate fetus model and using it for the study of drug clearance from fetus.

He has supervised more than 20 biomedical engineering projects at the postgraduate and senior undergraduate level.
 

Research | Current

Dr Ho is the Principle Investigator for the following research projects:

  • "Womb with a view": Software connecting pregnant women and fetus (2017-2019): $200k
  • Augmented Reality aided liver ablation (2017-2019): $100k
  • Bridging MedTech CoRE (NZ) and Computational Anatomy (Japan) through Abdominal Organ Modelling (2016-2018): $80k
  • Projects with Tobacco Control Research Tūranga (2014-2016): $140k
  • Fundamental re-design of catheters for draining complex collections (2015-2016): $32k

He has also been a co-investigator in medical/agricultural research projects/programme funded by MBIE Research Programme (AgResearch, 2016-2021), MBIE Smart Idea (Dept of Surgery, UoA, 2016-2018), and the Norwegian Research Council (Norsvin, 2018-2021). 

He is currently  leading a group of students working on computational models for the virtual liver and the virtual fetus. Specifically we study the hepatic and fetal circulation, drug metabolism & clearance (in particular acetaminophen and nicotine). 

Dr Ho holds grants that can support short term research projects in the biomedical and agricultural domain. If you are interested in working in these areas, please contact Dr Ho for further details of the projects.
 

Teaching | Current

ENGSCI753 "Computational Methods for Continuum Mechanics"
 

Postgraduate supervision

Zhe Yang, PhD, 2018- 

Renfei Ma, PhD, 2016- (co-supervisor)

Hao Bo Yu, ME, 2016-2017

Tay Wee Kiat (Victoria U. of Wellington), ME, 2016-2017 (co-supervisor)

Aurélien Bourgais (Arts et Métiers ParisTech), ME, 2015 (co-supervisor)

Armond Patoir (Arts et Métiers ParisTech), ME, 2014 (co-supervisor)

 

Responsibilities

  • Supervision of postgraduate and senior undergraduate students

Areas of expertise

  • Computational/mathematical modelling for cerebral and hepatic circulations
  • Physiologically base pharmacokinectics (PBPK) modelling
  • Computer aided hepatic surgery
  • Medical Information system design and implementation
  • 3D graphics & software engineering (Python, VB, Matlab, C++)
     

Selected publications and creative works (Research Outputs)

  • Ho, H., & Means, S. (2018). A Spatial-Temporal Model for Zonal Hepatotoxicity of Acetaminophen. Paper presented at Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, San Francisco, CA. 9 November - 13 November 2018. HEPATOLOGY. (pp. 1).
  • Ho, H., Yu, H. B., Gangsei, L. E., & Kongsro, J. (2018). A CT-image based pig atlas model and its potential applications in the meat industry. Meat science, 148, 1-4. 10.1016/j.meatsci.2018.09.011
  • Guo, H., Wang, C., Liu, Z., Gu, H., Li, Y., Zhao, L., ... Hao, Z. (2018). Quantification of in vivo gastric fluid volume in Bama miniature pigs in fasted state. BIOPHARMACEUTICS & DRUG DISPOSITION, 39 (8), 403-407. 10.1002/bdd.2155
  • Yu, H. B., & Ho, H. (2018). Methods and apparatus for tracking internal structures in soft objects: A phantom-based study. International Conference Image and Vision Computing New Zealand. 10.1109/IVCNZ.2017.8402449
  • Barléon N, Clarke, R. J., & Ho, H. (2018). Novel methods for segment-specific blood flow simulation for the liver. Computer Methods in Biomechanics and Biomedical Engineering10.1080/10255842.2018.1520224
    Other University of Auckland co-authors: Richard Clarke
  • Yu, H. B., & Ho, H. (2018). System Designs for Augmented Reality Based Ablation Probe Tracking. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 10.1007/978-3-319-75786-5_8
  • Ho, H. (2017). Womb with a view: Software connecting pregnant women and fetus [Computer software].
  • Yu, H., Ho, H., Bartlett, A., & Hunter, P. (2017). Modelling respiration induced torso deformation using a mesh fitting algorithm. Lecture Notes in Computer Science: Computer Vision – ACCV 2016 Workshops, 10117, 625-634. Taipei, Taiwan: Springer Verlag. 10.1007/978-3-319-54427-4_45
    URL: http://hdl.handle.net/2292/34142
    Other University of Auckland co-authors: Adam Bartlett, Peter Hunter