Associate Professor Ian John LeGrice

BE, DipTP, BHB, MBChB, PhD (jointly with Physiology)

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Associate Professor - Medical
Honorary Academic

Biography

Ian began his academic career with a Bachelor of Engineering in Civil Engineering from the University of Auckland, following it with a Diploma of Town Planning (DipTP). He subsequently went on to study Medicine at Auckland, obtaining his Bachelor of Human Biology (BHB), and then a Bachelor of Medicine and Bachelor of Surgery (MBChB). After briefly practicing medicine he returned to the University to obtain a PhD in Physiology.

After his PhD work on structure and electrical activation of the cardiac ventricles at the University of Auckland, Ian did his postdoctoral work on cardiac mechanics with Professor James Covell at the University of California, San Diego. After 2 years at UCSD, Ian returned to a lectureship in the Department of Physiology at the University of Auckland in 1994. In this position, Ian has had significant administrative and teaching roles in the Medical Programme.
 

Research | Current

Ian continues his research into the relationship between structure and function in the heart as a member of the Auckland Bioengineering Institute, closely collaborating with Bruce Smaill. This work has developed from the earlier focus on the normal cardiac function, to investigating the effects of diseases, such as hypertension and myocadial infarction, on cardiac structure and function.


Research groups and projects:

Selected publications and creative works (Research Outputs)

  • Wilson, A. J., Sands, G. B., Wang, V. Y., Hasaballa, A., Pontre, B., Young, A. A., ... LeGrice, I. J. (2020). Myocardial Laminar Organization Is Retained in Angiotensin-Converting Enzyme Inhibitor Treated SHRs. EXPERIMENTAL MECHANICS10.1007/s11340-020-00622-4
    Other University of Auckland co-authors: Gregory Sands, Vicky Wang, Alistair Young, Martyn Nash
  • Kelch, I. D., Bogle, G., Sands, G. B., Phillips, A. R. J., LeGrice, I. J., & Dunbar, P. R. (2019). High-resolution 3D imaging and topological mapping of the lymph node conduit system. PLoS biology, 17 (12)10.1371/journal.pbio.3000486
    Other University of Auckland co-authors: Anthony Phillips, Inken Kelch, Gib Bogle, Gregory Sands, Rod Dunbar
  • Hasaballa, A. I., Wang, V. Y., Sands, G. B., Wilson, A. J., Young, A. A., LeGrice, I. J., & Nash, M. P. (2019). Microstructurally Motivated Constitutive Modeling of Heart Failure Mechanics. Biophysical journal, 117 (12), 2273-2286. 10.1016/j.bpj.2019.09.038
    URL: http://hdl.handle.net/2292/52383
    Other University of Auckland co-authors: Gregory Sands, Vicky Wang, Alistair Young, Martyn Nash
  • Abukar, Y., Lever, N., Pachen, M., LeGrice, I. J., & Ramchandra, R. (2019). Impaired Baroreflex Function in an Ovine Model of Chronic Heart Failure Induced by Multiple Coronary Microembolizations. FRONTIERS IN PHYSIOLOGY, 1010.3389/fphys.2019.01420
    Other University of Auckland co-authors: Rohit Ramchandra, Nigel Lever
  • Abukar, Y., LeGrice, I., Lever, N., Paton, J. F. R., & Ramchandra, R. (2019). Restoring respiratory sinus arrhythmia to improve cardiac function in ovine heart failure. ACTA PHYSIOLOGICA. (pp. 1).
    Other University of Auckland co-authors: Rohit Ramchandra, Julian Paton
  • Trew, M. L., Engelman, Z. J., Caldwell, B. J., Lever, N. A., LeGrice, I. J., & Smaill, B. H. (2019). Cardiac intramural electrical mapping reveals focal delays but no conduction velocity slowing in the peri-infarct region. American journal of physiology. Heart and circulatory physiology, 317 (4), H743-H753. 10.1152/ajpheart.00154.2019
    Other University of Auckland co-authors: Bruce Smaill, Mark Trew, Nigel Lever
  • Ashton, J. L., Trew, M. L., LeGrice, I. J., Paterson, D. J., Paton, J. F., Gillis, A. M., & Smaill, B. H. (2019). Shift of leading pacemaker site during reflex vagal stimulation and altered electrical source-to-sink balance. The Journal of physiology, 597 (13), 3297-3313. 10.1113/jp276876
    Other University of Auckland co-authors: Jesse Ashton, Julian Paton, Mark Trew, Bruce Smaill
  • Vigneshwaran, V., Sands, G. B., LeGrice, I. J., Smaill, B. H., & Smith, N. P. (2019). Reconstruction of coronary circulation networks: A review of methods. Microcirculation (New York, N.Y. : 1994), 26 (5)10.1111/micc.12542
    URL: http://hdl.handle.net/2292/51497
    Other University of Auckland co-authors: Nic Smith, Gregory Sands, Bruce Smaill

Identifiers

Contact details

Primary office location

M&HS BUILDING 503 - Bldg 503
Level 4, Room 401B
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand

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