Associate Professor Ian John LeGrice

BE, DipTP, BHB, MBChB, PhD (jointly with Physiology)

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Associate Professor - Medical
Honorary Academic

Biography

Ian began his academic career with a Bachelor of Engineering in Civil Engineering from the University of Auckland, following it with a Diploma of Town Planning (DipTP). He subsequently went on to study Medicine at Auckland, obtaining his Bachelor of Human Biology (BHB), and then a Bachelor of Medicine and Bachelor of Surgery (MBChB). After briefly practicing medicine he returned to the University to obtain a PhD in Physiology.

After his PhD work on structure and electrical activation of the cardiac ventricles at the University of Auckland, Ian did his postdoctoral work on cardiac mechanics with Professor James Covell at the University of California, San Diego. After 2 years at UCSD, Ian returned to a lectureship in the Department of Physiology at the University of Auckland in 1994. In this position, Ian has had significant administrative and teaching roles in the Medical Programme.
 

Research | Current

Ian continues his research into the relationship between structure and function in the heart as a member of the Auckland Bioengineering Institute, closely collaborating with Bruce Smaill. This work has developed from the earlier focus on the normal cardiac function, to investigating the effects of diseases, such as hypertension and myocadial infarction, on cardiac structure and function.


Research groups and projects:

Selected publications and creative works (Research Outputs)

  • Trew, M. L., Engelman, Z. J., Caldwell, B. J., Lever, N. A., LeGrice, I. J., & Smaill, B. H. (2019). Cardiac intramural electrical mapping reveals focal delays but no conduction velocity slowing in the peri-infarct region. American journal of physiology. Heart and circulatory physiology, 317 (4), H743-H753. 10.1152/ajpheart.00154.2019
    Other University of Auckland co-authors: Bruce Smaill, Mark Trew, Nigel Lever
  • Vigneshwaran, V., Sands, G. B., LeGrice, I. J., Smaill, B. H., & Smith, N. P. (2019). Reconstruction of coronary circulation networks: A review of methods. Microcirculation (New York, N.Y. : 1994), 26 (5)10.1111/micc.12542
    Other University of Auckland co-authors: Nic Smith, Gregory Sands, Bruce Smaill
  • Ashton, J. L., Trew, M. L., LeGrice, I. J., Paterson, D. J., Paton, J. F., Gillis, A. M., & Smaill, B. H. (2019). Shift of leading pacemaker site during reflex vagal stimulation and altered electrical source-to-sink balance. The Journal of physiology10.1113/jp276876
    Other University of Auckland co-authors: Jesse Ashton, Julian Paton, Mark Trew, Bruce Smaill
  • Ramlugun, G. S., Zhao, J., Sands, G. B., Le Grice, I. J., & Smaill, B. H. (2019). Progression of Atrial Electrical Dysfunction in Hypertensive Heart Disease. Paper presented at Heart Rhythm 40th Scientific Sessions, San Francisco, CA. 8 May - 11 May 2019. Heart Rhythm. 10.1016/j.hrthm.2019.04.020
    URL: http://hdl.handle.net/2292/47816
    Other University of Auckland co-authors: Gregory Sands
  • Bear, L. R., LeGrice, I. J., Sands, G. B., Lever, N. A., Loiselle, D. S., Paterson, D. J., ... Smaill, B. H. (2018). How Accurate Is Inverse Electrocardiographic Mapping? A Systematic In Vivo Evaluation. Circulation. Arrhythmia and electrophysiology, 11 (5)10.1161/circep.117.006108
    Other University of Auckland co-authors: Denis Loiselle, Gregory Sands, Bruce Smaill, Nigel Lever
  • Caldwell, B. J., Trew, M. L., Le Grice, I., & Smaill, B. (2017). Development of 3D intramural and surface potentials in the LV: microstructural basis of preferential transmural conduction. Journal of Cardiovascular Electrophysiology, 28 (6), 692-701. 10.1111/jce.13207
    Other University of Auckland co-authors: Mark Trew, Bruce Smaill
  • Caldwell, B. J., Trew, M. L., Legrice, I. J., & Smaill, B. H. (2017). Development of 3-D Intramural and Surface Potentials in the LV: Microstructural Basis of Preferential Transmural Conduction.. Journal of cardiovascular electrophysiology. 10.1111/jce.13207
    Other University of Auckland co-authors: Mark Trew, Bruce Smaill
  • Ashton, J. L., Le Grice, I. J., Paterson, D. J., Paton, J. F. R., Trew, M. L., Gillis, A. M., & Smaill, B. H. (2017). Shift of dominant pacemaker site during reflex vagal stimulation is the result of propagation failure. Paper presented at Heart Rhythm Society 38th Annual Scientific Sessions, Chicago, USA. 10 May - 13 May 2017. Heart Rhythm. 10.1016/j.hrthm.2017.04.010
    URL: http://hdl.handle.net/2292/36683
    Other University of Auckland co-authors: Jesse Ashton, David Paterson, Julian Paton, Mark Trew, Bruce Smaill

Identifiers

Contact details

Primary office location

M&HS BUILDING 503 - Bldg 503
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand

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