Dr James Frederick Cheeseman

PhD, MSc (First Class Honours), BSc

Senior Lecturer

In: Anaesthesiology » School of Medicine » Faculty of Medical and Health Sciences

Research | Current

My research in chronobiology has two broad themes. The first is a programme of research investigating the effects of general anaesthesia on the circadian clock. This incorporates work from invertebrate and mammalian animal models (Drosophila, Honey bee and mouse) as well as clinical trials. The research combines investigation of the fundamental molecular components and animals’ physiology with the downstream behaviour. A particular current focus is the circadian Drosophila research programme in which my students and I are using transgenic reporter lines to investigate the development of the clock. The second main theme of my research is the study of the biological rhythms in the marine environment. This is in close association with the School of Biological Sciences. Specifically, this work includes investigation of the semilunar and tidal clocks predominantly in invertebrate models.

Teaching | Current

Undergraduate

Course Director and Lecturer, Qual300, Quality and Safety Workshop, School of Medicine
Lecturer, BIOSCI207, Adaptive Design, School of Biological Sciences
Lecturer, BIOSCI337, Animal Behaviour, School of Biological Sciences

Postgraduate

Course Director and Lecturer, MEDSCI718, Pharmacology of Anaesthetics and Analgesics.
Course Coordinator and Lecturer, MEDSCI738, Biological Rhythms
Lecturer, BIOSCI728, Neuroethology

Postgraduate supervision

I currently supervise or co-supervise five PhD students in the Faculty of Medical and Health Sciences. I have several projects available for post graduate students at the MSc and PhD level. I welcome applications or expressions of interest from students who are interested in the general circadian research themes described.

Distinctions/Honours

2011 University of Auckland Teaching Excellence Award for excellence in collaboration, Quality and Saftey Workshop

Committees/Professional groups/Services

School of Medicine Post Graduate Education and Training Committee - Chair

Faculty of Medical and Health Sciences Education Committee

Faculty of Medical and Health Sciences Medical Programme Board of Studies

Faculty of Medical and Health Sciences Academic Programmes Subcommittee

Department of Anaesthesiology Post Graduate Committee

Selected publications and creative works (Research Outputs)

Zhao, J., Warman, G. R., & Cheeseman, J. F. (2019). The functional changes of the circadian system organization in aging. Ageing research reviews, 52, 64-71. 10.1016/j.arr.2019.04.006
Other University of Auckland co-authors: Guy Warman
Zhao, J., Warman, G. R., Stanewsky, R., & Cheeseman, J. F. (2019). Development of the Molecular Circadian Clock and Its Light Sensitivity in Drosophila Melanogaster. Journal of biological rhythms10.1177/0748730419836818
Other University of Auckland co-authors: Guy Warman
Parkar, S. G., Kalsbeek, A., & Cheeseman, J. F. (2019). Potential Role for the Gut Microbiota in Modulating Host Circadian Rhythms and Metabolic Health. MICROORGANISMS, 7 (2)10.3390/microorganisms7020041
Menzel, R., Tison, L., Fischer-Nakai, J., Cheeseman, J., Balbuena, M. S., Chen, X., ... Greggers, U. (2019). Guidance of navigating honeybees by learned elongated ground structures. Frontiers in Behavioral Neuroscience, 12.10.3389/fnbeh.2018.00322
Orts-Sebastian, A., Ludin, N. M., Pawley, M. D. M., Cheeseman, J. F., & Warman, G. R. (2019). Impact of anaesthesia on circadian rhythms and implications for laboratory experiments. Experimental neurology, 311, 318-322. 10.1016/j.expneurol.2018.09.017
Other University of Auckland co-authors: Matthew Pawley, Guy Warman, Nicola Ludin
Zhao, J., Warman, G. R., & Cheeseman, J. F. (2018). Clock gene expression and locomotor activity predict death in the last days of life in Drosophila melanogaster. Scientific reports, 8 (1)10.1038/s41598-018-30323-x
Other University of Auckland co-authors: Guy Warman
Poulsen, R. C., Warman, G. R., Sleigh, J., Ludin, N. M., & Cheeseman, J. F. (2018). How does general anaesthesia affect the circadian clock?. Sleep Medicine Reviews, 37, 35-44. 10.1016/j.smrv.2016.12.002
URL: http://hdl.handle.net/2292/43712
Other University of Auckland co-authors: Guy Warman, Raewyn Poulsen, Nicola Ludin, Jamie Sleigh
Du, L. Y., Darroch, H., Keerthisinghe, P., Ashimbayeva, E., Astin, J. W., Crosier, K. E., ... Hall, C. J. (2017). The innate immune cell response to bacterial infection in larval zebrafish is light-regulated. Scientific Reports, 7 (1).10.1038/s41598-017-12842-1
URL: http://hdl.handle.net/2292/41034
Other University of Auckland co-authors: Christopher Hall, Jonathan Astin, Guy Warman