Dr Jules Bertrand Luc Devaux

PhD, MSc, BSc

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Research Technician
Doctoral Candidate - Doctor of Philosophy

Research | Current

Ultimately, my research focuses on the mitochondrial function and its implication in species physiology, response to environmental challenges and impact in diseases.

Using natural models, my research addressed some physiological adaptations that species have evolved to tolerate environmental fluctuations, this with a special emphasis on the mitochondrial function.

My last projects assessed the effect of environmental factors such as temperature, oxygen and acidosis on fundamental mitochondrial processes. These include energy transfer, redox balance, free radical management, ion balance and overall mitochondrial fitness.

 

Areas of expertise

Mitochondrial physiology, respirometry, fluorimetry, spectrophotometry.

Selected publications and creative works (Research Outputs)

  • Farhat, F., Simon, B., Amerand, A., Devaux, J., Belhomme, M., Calves, P., & Moisan, C. (2020). Exercise training changes mitochondrial function and its vulnerability to reactive oxygen species exposure differently in male and female silver European eels. ENVIRONMENTAL BIOLOGY OF FISHES, 103 (4), 363-375. 10.1007/s10641-020-00962-z
  • Hunter, F. W., Devaux, J. B. L., Meng, F., Hong, C. R., Khan, A., Tsai, P., ... Marastoni, S. (2019). Functional CRISPR and shRNA Screens Identify Involvement of Mitochondrial Electron Transport in the Activation of Evofosfamide. Molecular pharmacology, 95 (6), 638-651. 10.1124/mol.118.115196
    Other University of Auckland co-authors: Francis Hunter, Stefan Bohlander, Peter Tsai, Purvi Kakadiya, Tony Hickey, Cristin Print
  • Horscroft, J. A., O'Brien KA, Clark, A. D., Lindsay, R. T., Steel, A. S., Procter, N. E. K., ... Murray, A. J. (2019). Inorganic nitrate, hypoxia, and the regulation of cardiac mitochondrial respiration-probing the role of PPARα. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33 (6), 7563-7577. 10.1096/fj.201900067R
  • Hedges, C. P., Wilkinson, R. T., Devaux, J. B. L., & Hickey, A. J. R. (2019). Hymenoptera flight muscle mitochondrial function: Increasing metabolic power increases oxidative stress. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 230, 115-121. 10.1016/j.cbpa.2019.01.002
    Other University of Auckland co-authors: Chris Hedges, Tony Hickey
  • O'Brien KA, Horscroft, J. A., Devaux, J., Lindsay, R. T., Steel, A. S., Clark, A. D., ... Murray, A. J. (2019). PPARα-independent effects of nitrate supplementation on skeletal muscle metabolism in hypoxia. Biochimica et biophysica acta. Molecular basis of disease, 1865 (4), 844-853. 10.1016/j.bbadis.2018.07.027
  • Devaux, J. B. L., Hickey, A. J. R., & Renshaw, G. M. C. (2019). Mitochondrial plasticity in the cerebellum of two anoxia-tolerant sharks: contrasting responses to anoxia/re-oxygenation. The Journal of experimental biology, 222 (Pt 6).10.1242/jeb.191353
    Other University of Auckland co-authors: Tony Hickey
  • Devaux, J. B. (2019). Mitochondrial adaptations involved in hypoxia and anoxia-tolerance of intertidal fish The University of Auckland. ResearchSpace@Auckland.
    URL: http://hdl.handle.net/2292/49335
  • Devaux, J. B. L., Hedges, C. P., Birch, N., Herbert, N., Renshaw, G. M. C., & Hickey, A. J. R. (2018). Acidosis Maintains the Function of Brain Mitochondria in Hypoxia-Tolerant Triplefin Fish: A Strategy to Survive Acute Hypoxic Exposure?. Frontiers in physiology, 910.3389/fphys.2018.01941
    Other University of Auckland co-authors: Tony Hickey, Chris Hedges, Neill Herbert

Identifiers

Contact details

Primary office location

M&HS BUILDING 503 - Bldg 503
Level 5, Room 501
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand

Social links

Web links