Dr Jagdish Kumar Jaiswal

BPharm, MPharm, PhD

Biography

  • B. Pharm - Institute of Technology, Banaras Hindu University (India)
  • M. Pharm (Pharmaceutics) - Jadavpur University (India)
  • PhD (Pharmacology) - All India Institute of Medical Sciences (India)
  • Visiting DAAD Fellow in the laboratories of Prof. Jorg Kreuter at Frankfurt Biocentre, Johann Wolfgang Goethe University, Germany
  • Research Associate (Drug Discovery- Pharmacology)-  Torrent Research Centre, India
  • Post doctoral research fellow - Auckland Cancer Society Research Centre (2005-2007)

Research interests

Current Projects

Small molecules perforin inhibitor (Wellcome Trust, UK)

Past projects

  • Clinical Phase I candidate PR-610. Pre-clinical pharmacokinetic studies (PIs- Drs Adam Patterson and Jeff Smaiil)
  • Clinical Phase II/III candidate PR-104. Formulation stability and rat toxicity study (Principal Investigator - Prof. Bill Wilson)
  • Clinical development candidate CEN-209 (SN30000). preclinical ADME studies (Principal Investigator - Prof. Bill Wilson)
  • NitroCBI analogs. Preclinical  ADME studies (Principal Investigators Drs. Frederik Pruijn and Moana Tercel)

Research | Current

  • ADME/Tox of anti cancer drugs in pre-clinical development
  • LC-MS/MS method development

Postgraduate supervision

Small animal pharmacokinetic studies

Bioanalysis

Responsibilities

Pre clinical DMPK studies (small animals)

Bio-analysis (LC-MS/MS, LC-MS, Ion trap, HPLC)
 

Areas of expertise

Preclinical drug development of small molecules

Measurement of drug, metabolites in biological matrix (serum, plasma, saliva etc) by LC-MS/MS, HPLC.

Selected publications and creative works (Research Outputs)