Dr Jo Kate Perry

PhD, BSc (Hons)

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Associate Director - Academic

Biography

Dr Perry is a cell and molecular biologist with expertise in endocrinology and oncology. Her research interests lie in the involvement of growth factors and hormones in human development and disease including complications of pregnancy and cancer.

Dr Perry completed her PhD at the Institute of Cancer Research in London and was awarded a National Health and Medical Research Council (NHMRC) Peter Doherty Postdoctoral Fellowship to work at the Murdoch Childrens Research Institute in Melbourne. She joined the Liggins Institute in 2005.

 

Research | Current

  • The role of placental growth hormone in the development and function of the placenta.
  • The contribution of human growth hormone to cancer progression and the mechanistic interactions of this hormone with conventional cancer therapies used clinically.
  • Developing small molecule targeted therapies directed against the human growth hormone receptor.

Other research and teaching interests


  • Liggins Education Network for Science (LENScience)

 

Committees/Professional groups/Services

  • Auckland Cancer Research Network

Selected publications and creative works (Research Outputs)

  • Abdel-Fatah, T. M. A., Broom, R. J., Lu, J., Moseley, P. M., Huang, B., Li, L., ... Cao, W. (2019). SHON expression predicts response and relapse risk of breast cancer patients after anthracycline-based combination chemotherapy or tamoxifen treatment. British journal of cancer, 120 (7), 728-745. 10.1038/s41416-019-0405-x
  • Lu, M., Flanagan, J. U., Langley, R. J., Hay, M. P., & Perry, J. K. (2019). Targeting growth hormone function: strategies and therapeutic applications. Signal transduction and targeted therapy, 410.1038/s41392-019-0036-y
    Other University of Auckland co-authors: Michael Hay, Ries Langley
  • Jacobson, E. C., Perry, J. K., Long, D. S., Olins, A. L., Olins, D. E., Wright, B. E., ... O'Sullivan JM (2018). Migration through a small pore disrupts inactive chromatin organization in neutrophil-like cells. BMC biology, 16 (1)10.1186/s12915-018-0608-2
    URL: http://hdl.handle.net/2292/46266
    Other University of Auckland co-authors: Mark Vickers, Justin O'Sullivan
  • Nyaga, D. M., Vickers, M. H., Jefferies, C., Perry, J. K., & O'Sullivan JM (2018). Type 1 Diabetes Mellitus-Associated Genetic Variants Contribute to Overlapping Immune Regulatory Networks. FRONTIERS IN GENETICS, 910.3389/fgene.2018.00535
    URL: http://hdl.handle.net/2292/45762
    Other University of Auckland co-authors: Mark Vickers, Justin O'Sullivan
  • Liao, S., Vickers, M. H., Stanley, J. L., Baker, P. N., & Perry, J. K. (2018). Human Placental Growth Hormone Variant in Pathological Pregnancies. Endocrinology, 159 (5), 2186-2198. 10.1210/en.2018-00037
    Other University of Auckland co-authors: Mark Vickers
  • Liao, S., Vickers, M. H., Taylor, R. S., Jones, B., Fraser, M., McCowan, L. M. E., ... Perry, J. K. (2017). Maternal serum IGF-1, IGFBP-1 and 3, and placental growth hormone at 20 weeks' gestation in pregnancies complicated by preeclampsia. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 10, 149-154. 10.1016/j.preghy.2017.07.148
    URL: http://hdl.handle.net/2292/36804
    Other University of Auckland co-authors: Mhoyra Fraser, Mark Vickers, Lesley McCowan, Rennae Taylor, Beatrix Jones
  • Reynolds, C. M., Perry, J. K., & Vickers, M. H. (2017). Manipulation of the growth hormone-insulin-like growth factor (GH-IGF) axis: A treatment strategy to reverse the effects of early life developmental programming. International Journal of Molecular Sciences, 18 (8).10.3390/ijms18081729
    URL: http://hdl.handle.net/2292/44058
    Other University of Auckland co-authors: Mark Vickers, Clare Reynolds
  • Perry, J. K., Wu, Z.-S., Mertani, H. C., Zhu, T., & Lobie, P. E. (2017). Tumour-derived human growth hormone as a therapeutic target in oncology. Trends in Endocrinology & Metabolism, 28 (8), 587-596. 10.1016/j.tem.2017.05.003

Identifiers

Contact details

Primary office location

M&HS BUILDING 505 - Bldg 505
Level 2, Room 202H
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand

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