Dr Jo Kate Perry
PhD, BSc (Hons)
Dr Perry is a cell and molecular biologist with expertise in endocrinology and oncology. Her research interests lie in the involvement of growth factors and hormones in human development and disease including complications of pregnancy and cancer.
Dr Perry completed her PhD at the Institute of Cancer Research in London and was awarded a National Health and Medical Research Council (NHMRC) Peter Doherty Postdoctoral Fellowship to work at the Murdoch Childrens Research Institute in Melbourne. She joined the Liggins Institute in 2005.
Research | Current
- The role of placental growth hormone in the development and function of the placenta.
- The contribution of human growth hormone to cancer progression and the mechanistic interactions of this hormone with conventional cancer therapies used clinically.
- Developing small molecule targeted therapies directed against the human growth hormone receptor.
Other research and teaching interests
- Liggins Education Network for Science (LENScience)
- Auckland Cancer Research Network
Selected publications and creative works (Research Outputs)
- Jacobson, E., Vickers, M. H., Perry, J. K., & O'Sullivan JM (2018). Genome organization: connecting the developmental origins of disease and genetic variation. Journal of developmental origins of health and disease, 9 (3), 260-265. 10.1017/s2040174417000678
Other University of Auckland co-authors: Justin O'Sullivan, Mark Vickers
- Liao, S., Vickers, M. H., Stanley, J. L., Baker, P. N., & Perry, J. K. (2018). Human Placental Growth Hormone Variant in Pathological Pregnancies. Endocrinology, 159 (5), 2186-2198. 10.1210/en.2018-00037
Other University of Auckland co-authors: Mark Vickers
- Liao, S., Vickers, M. H., Taylor, R. S., Jones, B., Fraser, M., McCowan, L. M. E., ... Perry, J. K. (2017). Maternal serum IGF-1, IGFBP-1 and 3, and placental growth hormone at 20 weeks' gestation in pregnancies complicated by preeclampsia. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 10, 149-154. 10.1016/j.preghy.2017.07.148
Other University of Auckland co-authors: Mhoyra Fraser, Mark Vickers, Lesley McCowan, Rennae Taylor, Beatrix Jones
- Reynolds, C. M., Perry, J. K., & Vickers, M. H. (2017). Manipulation of the growth hormone-insulin-like growth factor (GH-IGF) axis: A treatment strategy to reverse the effects of early life developmental programming. International Journal of Molecular Sciences, 18 (8).10.3390/ijms18081729
Other University of Auckland co-authors: Mark Vickers, Clare Reynolds
- Perry, J. K., Wu, Z.-S., Mertani, H. C., Zhu, T., & Lobie, P. E. (2017). Tumour-derived human growth hormone as a therapeutic target in oncology. Trends in Endocrinology & Metabolism, 28 (8), 587-596. 10.1016/j.tem.2017.05.003
- Liao, S., Vickers, M. H., Taylor, R. S., Fraser, M., McCowan, L. M., Baker, P. N., & Perry, J. K. (2017). Maternal serum placental growth hormone, insulin-like growth factors and their binding proteins at 20 weeks' gestation in pregnancies complicated by gestational diabetes mellitus. Hormones, 16 (3), 282-290. 10.14310/horm.2002.1747
Other University of Auckland co-authors: Mark Vickers, Rennae Taylor, Mhoyra Fraser, Lesley McCowan
- Liao, S., Vickers, M. H., Taylor, R. S., Jones, B., Fraser, M., McCowan, L. M. E., ... Perry, J. K. (2016). Human placental growth hormone is increased in maternal serum at 20 weeks of gestation in pregnancies with large-for-gestational-age babies. Growth Factors, 34 (5-6), 203-209. 10.1080/08977194.2016.1273223
Other University of Auckland co-authors: Mark Vickers, Rennae Taylor, Mhoyra Fraser, Lesley McCowan, Beatrix Jones
- Evans, A., Jamieson, S. M. F., Liu, D. X., Wilson, W. R., & Perry, J. K. (2016). Growth hormone receptor antagonism suppresses tumour regrowth after radiotherapy in an endometrial cancer xenograft model. Cancer Letters, 379 (1), 117-123. 10.1016/j.canlet.2016.05.031
Other University of Auckland co-authors: William Wilson, Stephen Jamieson