Dr Jo Perry

PhD, BSc (Hons)

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Assoc Dean Postgraduate
Senior Research Fellow

Biography

Dr Perry is a cell and molecular biologist with expertise in endocrinology and oncology. Her research interests lie in the involvement of growth factors and hormones in human development and disease including complications of pregnancy and cancer.

Dr Perry completed her PhD at the Institute of Cancer Research in London and was awarded a National Health and Medical Research Council (NHMRC) Peter Doherty Postdoctoral Fellowship to work at the Murdoch Childrens Research Institute in Melbourne. She joined the Liggins Institute in 2005.

 

Research | Current

  • The contribution of human growth hormone to cancer progression and the mechanistic interactions of this hormone with conventional cancer therapies used clinically.
  • Development of novel antagonists of the human growth hormone receptor.
  • The role of placental growth hormone in the development and function of the placenta.

Other research and teaching interests

  • Liggins Education Network for Science (LENScience)

 

Teaching | Current

MEDSCI 302; PHARM 411

Committees/Professional groups/Services

  • Auckland Cancer Research Network

Selected publications and creative works (Research Outputs)

  • Tamshen, K., Wang, Y., Jamieson, S. M. F., Perry, J. K., & Maynard, H. D. (2020). Genetic Code Expansion Enables Site-Specific PEGylation of a Human Growth Hormone Receptor Antagonist through Click Chemistry. Bioconjugate chemistry, 31 (9), 2179-2190. 10.1021/acs.bioconjchem.0c00365
    Other University of Auckland co-authors: Stephen Jamieson
  • Wang, Y., Langley, R. J., Tamshen, K., Jamieson, S. M., Lu, M., Maynard, H. D., & Perry, J. K. (2020). Long-Acting Human Growth Hormone Receptor Antagonists Produced in E. coli and Conjugated with Polyethylene Glycol. Bioconjugate chemistry, 31 (6), 1651-1660. 10.1021/acs.bioconjchem.0c00208
    Other University of Auckland co-authors: Ries Langley, Stephen Jamieson
  • Jain, L., Fadason, T., Schierding, W., Vickers, M. H., O'Sullivan JM, & Perry, J. K. (2020). 3D interactions with the growth hormone locus in cellular signalling and cancer-related pathways. Journal of molecular endocrinology, 64 (4), 209-222. 10.1530/jme-20-0010
    Other University of Auckland co-authors: Justin O'Sullivan, William Schierding, Mark Vickers
  • Lu, M., Flanagan, J. U., Langley, R. J., Hay, M. P., & Perry, J. K. (2019). Targeting growth hormone function: strategies and therapeutic applications. Signal transduction and targeted therapy, 410.1038/s41392-019-0036-y
    Other University of Auckland co-authors: Michael Hay, Ries Langley, Jack Flanagan
  • Liao, S., Vickers, M. H., Stanley, J. L., Baker, P. N., & Perry, J. K. (2018). Human Placental Growth Hormone Variant in Pathological Pregnancies. Endocrinology, 159 (5), 2186-2198. 10.1210/en.2018-00037
    Other University of Auckland co-authors: Mark Vickers
  • Perry, J. K., Wu, Z.-S., Mertani, H. C., Zhu, T., & Lobie, P. E. (2017). Tumour-derived human growth hormone as a therapeutic target in oncology. Trends in Endocrinology & Metabolism, 28 (8), 587-596. 10.1016/j.tem.2017.05.003
  • Liao, S., Vickers, M. H., Taylor, R. S., Fraser, M., McCowan, L. M., Baker, P. N., & Perry, J. K. (2017). Maternal serum placental growth hormone, insulin-like growth factors and their binding proteins at 20 weeks' gestation in pregnancies complicated by gestational diabetes mellitus. Hormones, 16 (3), 282-290. 10.14310/horm.2002.1747
    Other University of Auckland co-authors: Mark Vickers, Rennae Taylor, Mhoyra Fraser, Lesley McCowan
  • Evans, A., Jamieson, S. M. F., Liu, D. X., Wilson, W. R., & Perry, J. K. (2016). Growth hormone receptor antagonism suppresses tumour regrowth after radiotherapy in an endometrial cancer xenograft model. Cancer Letters, 379 (1), 117-123. 10.1016/j.canlet.2016.05.031
    Other University of Auckland co-authors: Stephen Jamieson

Identifiers

Contact details

Primary office location

M&HS BUILDING 505 - Bldg 505
Level 2, Room 202H
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand

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