Professor Jamie Sleigh


Research | Current

The EEG and anaesthesia. Development of ester analogues of ketamine. Theoretical modelling of cortical changes in anaesthesia, sleep, and seizures.




  1. Waikato Kudos award – for Medical research 2007
  2. High-density EEG mapping during general anaesthesia with Xenon and Propofol: a pilot study. ANAESTHESIA AND INTENSIVE CARE: BEST PAPER AWARD 2003.
  3. D H Mckay, L J Voss, J W Sleigh, J P Barnard and E K Johannsen. Modelling the hypnotic effect of sevoflurane using the spectral entropy of the electroencephalogram.  Won first prize at the ANZCA conference Auckland 2005.
  4. R. W. Frengley, D. N. Closey, J. W. Sleigh, J. M. Torrance. The effect of closed system suction on airway pressures when using the Servo 300 ventilator. Won first prize at the World Society of ICU conference Sydney 2000.

Areas of expertise

Signal processing and EEG. Mechanisms of general anaesthesia and consciousness. Clinical anaesthesia.

Committees/Professional groups/Services



  1. Lecturer, Dept Anaesthesia University of Zimbabwe (1986-1988).
  2. Specialist Anaesthetist Wanganui Hospital (1988-1991).
  3. Specialist Anaesthetist/Senior Lecturer: Waikato Hospital/Auckland Medical School (1992-2001).
  4. Professor of Anaesthesiology and Intensive Care, Waikato Clinical School, University of Auckland (2001-present).
  5. Honorary Lecturer Department of Physics, University of Waikato



  • Fellow of Australian and New Zealand College of Anaesthestists: Part One examiner
  • University of Auckland, Faculty of Medical and Health Sciences - Waikato Representative, Board of Research

Selected publications and creative works (Research Outputs)

  • Hutt, A., Lefebvre, J., Hight, D., & Sleigh, J. (2018). Suppression of underlying neuronal fluctuations mediates EEG slowing during general anaesthesia. NeuroImage10.1016/j.neuroimage.2018.06.043
  • Chiang, N., Jain, J. K., Sleigh, J., & Vasudevan, T. (2018). Measuring Transcutaneous Oxygenation to Validate the Duration Required to Achieve Electrode Equilibration. Advances in Skin & Wound Care, 31 (6), 263-269. 10.1097/01.ASW.0000530847.49484.4b
  • Voss, L. J., Karalus, S., Englund, V., & Sleigh, J. W. (2018). Ketamine Action in the In Vitro Cortical Slice Is Mitigated by Potassium Channel Blockade. Anesthesiology, 128 (6), 1167-1174. 10.1097/aln.0000000000002147
  • Gaskell, A., Sanders, R. D., & Sleigh, J. (2018). Using EEG markers to titrate anaesthesia. British Journal of Anaesthesia10.1016/j.bja.2018.04.003
  • Sleigh, J. (2018). Probing the twilight zone of anaesthetic-induced composite consciousness. British Journal of Anaesthesia10.1016/j.bja.2018.04.026
  • Sleigh, J. (2018). Can nitric oxide tame the ketamine tiger?. British Journal of Anaesthesia, 120 (5), 890-891. 10.1016/j.bja.2018.02.013
  • Shalbaf, A., Saffar, M., Sleigh, J. W., & Shalbaf, R. (2018). Monitoring the Depth of Anesthesia Using a New Adaptive Neurofuzzy System. IEEE journal of biomedical and health informatics, 22 (3), 671-677. 10.1109/jbhi.2017.2709841
  • Liang, Z., Huang, C., Li, Y., Hight, D. F., Voss, L. J., Sleigh, J. W., ... Bai, Y. (2018). Emergence EEG pattern classification in sevoflurane anesthesia. Physiological measurement, 39 (4)10.1088/1361-6579/aab4d0