Professor Jamie Sleigh

MBChB FFARCS FANZCA FJFICM MD

Research | Current

The EEG and anaesthesia. Development of ester analogues of ketamine. Theoretical modelling of cortical changes in anaesthesia, sleep, and seizures.

Distinctions/Honours

 

SIGNIFICANT DISTINCTIONS / AWARDS

  1. Waikato Kudos award – for Medical research 2007
  2. High-density EEG mapping during general anaesthesia with Xenon and Propofol: a pilot study. ANAESTHESIA AND INTENSIVE CARE: BEST PAPER AWARD 2003.
  3. D H Mckay, L J Voss, J W Sleigh, J P Barnard and E K Johannsen. Modelling the hypnotic effect of sevoflurane using the spectral entropy of the electroencephalogram.  Won first prize at the ANZCA conference Auckland 2005.
  4. R. W. Frengley, D. N. Closey, J. W. Sleigh, J. M. Torrance. The effect of closed system suction on airway pressures when using the Servo 300 ventilator. Won first prize at the World Society of ICU conference Sydney 2000.

Areas of expertise

Signal processing and EEG. Mechanisms of general anaesthesia and consciousness. Clinical anaesthesia.

Committees/Professional groups/Services

 

PREVIOUS APPOINTMENTS

  1. Lecturer, Dept Anaesthesia University of Zimbabwe (1986-1988).
  2. Specialist Anaesthetist Wanganui Hospital (1988-1991).
  3. Specialist Anaesthetist/Senior Lecturer: Waikato Hospital/Auckland Medical School (1992-2001).
  4. Professor of Anaesthesiology and Intensive Care, Waikato Clinical School, University of Auckland (2001-present).
  5. Honorary Lecturer Department of Physics, University of Waikato

 

PROFESSIONAL SERVICE

  • Fellow of Australian and New Zealand College of Anaesthestists: Part One examiner
  • University of Auckland, Faculty of Medical and Health Sciences - Waikato Representative, Board of Research

Selected publications and creative works (Research Outputs)

  • Kaiser, H. A., Peus, M., Luedi, M. M., Lersch, F., Krejci, V., Reineke, D., ... Hight, D. (2020). Frontal electroencephalogram reveals emergence-like brain activity occurring during transition periods in cardiac surgery. British journal of anaesthesia, 125 (3), 291-297. 10.1016/j.bja.2020.05.064
  • Sleigh, J. W., & Gaskell, A. (2020). Postoperative Delirium: A Minefield of Markers and Mediators. Anesthesiology, 133 (2), 255-257. 10.1097/aln.0000000000003383
  • Voss, L. J., & Sleigh, J. W. (2020). A Metabolic Mechanism for Anaesthetic Suppression of Cortical Synaptic Function in Mouse Brain Slices-A Pilot Investigation. International journal of molecular sciences, 21 (13).10.3390/ijms21134703
  • Dimitrov, I. V., Harvey, M. G., Voss, L. J., Sleigh, J. W., Bickerdike, M. J., & Denny, W. A. (2020). Structure-Activity Relationships for the Anaesthetic and Analgaesic Properties of Aromatic Ring-Substituted Ketamine Esters. Molecules (Basel, Switzerland), 25 (12).10.3390/molecules25122950
    Other University of Auckland co-authors: Bill Denny
  • Vrijdag, X. C., van Waart, H., Sleigh, J. W., & Mitchell, S. J. (2020). Pupillometry is not sensitive to gas narcosis in divers breathing hyperbaric air or normobaric nitrous oxide. Diving and hyperbaric medicine, 50 (2), 115-120. 10.28920/dhm50.2.115-120
    URL: http://hdl.handle.net/2292/52576
    Other University of Auckland co-authors: Simon Mitchell, Xavier Vrijdag, Hanna van Waart
  • Gaskell, A. L., & Sleigh, J. W. (2020). An Introduction to Causal Diagrams for Anesthesiology Research. Anesthesiology, 132 (5), 951-967. 10.1097/aln.0000000000003193
    Other University of Auckland co-authors: Amy Gaskell
  • Kreuzer, M., Stern, M. A., Hight, D., Berger, S., Schneider, G., Sleigh, J. W., & García PS (2020). Spectral and Entropic Features Are Altered by Age in the Electroencephalogram in Patients under Sevoflurane Anesthesia. Anesthesiology, 132 (5), 1003-1016. 10.1097/aln.0000000000003182
  • Shalbaf, A., Shalbaf, R., Saffar, M., & Sleigh, J. (2020). Monitoring the level of hypnosis using a hierarchical SVM system. Journal of clinical monitoring and computing, 34 (2), 331-338. 10.1007/s10877-019-00311-1

Identifiers

Contact details

Primary office location

PETER ROTHWELL ACADEMIC CENTRE - Bldg 695
Level 0, Room 001
WAIKATO HOSPITAL SELWYN ST
HAMILTON CENTRAL
HAMILTON 3204
New Zealand

Web links