Professor Jamie Sleigh


Research | Current

The EEG and anaesthesia. Development of ester analogues of ketamine. Theoretical modelling of cortical changes in anaesthesia, sleep, and seizures.




  1. Waikato Kudos award – for Medical research 2007
  2. High-density EEG mapping during general anaesthesia with Xenon and Propofol: a pilot study. ANAESTHESIA AND INTENSIVE CARE: BEST PAPER AWARD 2003.
  3. D H Mckay, L J Voss, J W Sleigh, J P Barnard and E K Johannsen. Modelling the hypnotic effect of sevoflurane using the spectral entropy of the electroencephalogram.  Won first prize at the ANZCA conference Auckland 2005.
  4. R. W. Frengley, D. N. Closey, J. W. Sleigh, J. M. Torrance. The effect of closed system suction on airway pressures when using the Servo 300 ventilator. Won first prize at the World Society of ICU conference Sydney 2000.

Areas of expertise

Signal processing and EEG. Mechanisms of general anaesthesia and consciousness. Clinical anaesthesia.

Committees/Professional groups/Services



  1. Lecturer, Dept Anaesthesia University of Zimbabwe (1986-1988).
  2. Specialist Anaesthetist Wanganui Hospital (1988-1991).
  3. Specialist Anaesthetist/Senior Lecturer: Waikato Hospital/Auckland Medical School (1992-2001).
  4. Professor of Anaesthesiology and Intensive Care, Waikato Clinical School, University of Auckland (2001-present).
  5. Honorary Lecturer Department of Physics, University of Waikato



  • Fellow of Australian and New Zealand College of Anaesthestists: Part One examiner
  • University of Auckland, Faculty of Medical and Health Sciences - Waikato Representative, Board of Research

Selected publications and creative works (Research Outputs)

  • Hight, D. F., Gaskell, A. L., Kreuzer, M., Voss, L. J., García PS, & Sleigh, J. W. (2019). Transient electroencephalographic alpha power loss during maintenance of general anaesthesia. British journal of anaesthesia, 122 (5), 635-642. 10.1016/j.bja.2018.11.029
  • Hesse, S., Kreuzer, M., Hight, D., Gaskell, A., Devari, P., Singh, D., ... Sleigh, J. W. (2019). Association of electroencephalogram trajectories during emergence from anaesthesia with delirium in the postanaesthesia care unit: an early sign of postoperative complications. British journal of anaesthesia, 122 (5), 622-634. 10.1016/j.bja.2018.09.016
  • Jacobson, G. M., Voss, L. J., Klockars, A., Bird, S., Dimitrov, I., Denny, W. A., ... Harvey, M. G. (2019). Transcriptional changes in response to ketamine ester-analogs SN 35210 and SN 35563 in the rat brain. BMC genomics, 20 (1)10.1186/s12864-019-5649-6
    Other University of Auckland co-authors: Bill Denny
  • Dimitrov, I. V., Harvey, M. G., Voss, L. J., Sleigh, J. W., Bickerdike, M. J., & Denny, W. A. (2019). Ketamine esters and amides as short-acting anaesthetics: Structure-activity relationships for the side-chain. Bioorganic & medicinal chemistry, 27 (7), 1226-1231. 10.1016/j.bmc.2019.02.010
    Other University of Auckland co-authors: Bill Denny, Ivo Dimitrov
  • Sleigh, J. (2019). Is prespecification taking the search out of research?. Paediatric anaesthesia, 29 (3), 216-217. 10.1111/pan.13538
  • Gaskell, A., Pullon, R., Hight, D., Termaat, J., Mans, G., Voss, L., ... Rodriguez, A. (2019). Modulation of frontal EEG alpha oscillations during maintenance and emergence phases of general anaesthesia to improve early neurocognitive recovery in older patients: protocol for a randomised controlled trial. Trials, 20 (1)10.1186/s13063-019-3178-x
    Other University of Auckland co-authors: Rebecca Pullon
  • Pullon, R. M., McCabe, S., Gaskell, A., & Sleigh, J. W. (2019). Non-sinusoidal waves in the EEG and their simulated effect on anaesthetic quantitative EEG monitors. Journal of clinical monitoring and computing10.1007/s10877-019-00254-7
    Other University of Auckland co-authors: Rebecca Pullon
  • Shalbaf, A., Shalbaf, R., Saffar, M., & Sleigh, J. (2019). Monitoring the level of hypnosis using a hierarchical SVM system. Journal of Clinical Monitoring and Computing10.1007/s10877-019-00311-1


Contact details

Primary office location

Level 0, Room 000
New Zealand

Web links