Associate Professor Johanna Montgomery

PhD (Physiology), University of Otago

Associate Professor

In: Physiology » Medical Science » Faculty of Medical and Health Sciences

Biography

Associate Professor Johanna Montgomery completed her PhD in Physiology at the University of Otago. She then performed her postdoctoral research at Stanford University USA, where her research focus was the plasticity of synapses in the hippocampus. She returned to New Zealand in 2004 where she is Principal Investigator of the Synaptic Function Research Group in the Department of Physiology and Centre for Brain Research at the University of Auckland. Her research team focusses on understanding the molecular mechanisms that underlie the physiology of excitatory synapses in the central and peripheral nervous systems. Her laboratory combines electrophysiology, molecular biology and imaging techniques to investigate how changes in synapse function could underlie developmental disorders such as Autism, and neurodegenerative disorders such as Huntington's Disease. Recently, her research has expanded to examine how neuronal, synapse and myocyte plasticity may contribute to normal and abnormal heart rhythm.

Lab webpage: Synaptic Function Research Group

Lab members

Postdoctoral Fellows and Research Fellows: Dr Juliette Cheyne, Dr Annika Winbo, Dr Jesse Ashton, Dr Kevin Lee, Dr Yewon Jung
PhD students: Yuktiben Vyas, Beatriz Guzman, Giselle Wong

Teaching | Current

Course Director, Medsci 206: Introduction to Neuroscience

Course Director, Medsci 733: Advanced Methods in Cell Physiology

Currently teaching in:

Medsci 206: Introduction to Neuroscience

Medsci 317: Integrative Neuroscience

Medsci 727: Advanced Neuroscience

Medsci 733: Advanced Methods in Cell Physiology

Distinctions/Honours

2018: Physiological Society of New Zealand Excellence in Research Award

2016: Royal Society London Colin Pillinger International Exchanges Award

2015: Kellaway Medical Research Fellowship

2015: DAAD Research Stay Award, Germany

2010: Rand Research Award, Colwin Research Award, Marine Biological Laboratory, USA.

2007: University of Auckland Early Career Research Excellence Award

2005: Eppendorf and Science International Prize for Neurobiology, Finalist Award

2005: Fulbright New Zealand Award

2001: Servier Distinguished Young Investigator Award, presented by the International Union of Physiological Scientists

2000: Kathryn MacCormack Scholarship (Stanford University)

1998: Goddard Prize, Australasian Winter Conference on Brain Research

Areas of expertise

Electrophysiology (whole cell patch clamp) and cell biology.

Selected publications and creative works (Research Outputs)

Aqrawe, Z., Wright, B., Patel, N., Vyas, Y., Malmstrom, J., Montgomery, J. M., ... Svirskis, D. (2019). The influence of macropores on PEDOT/PSS microelectrode coatings for neuronal recording and stimulation. Sensors and Actuators, B: Chemical, 281, 549-560. 10.1016/j.snb.2018.10.099
Other University of Auckland co-authors: Zaid Aqrawe, Bryon Wright, Jenny Malmstrom, Jadranka Travas-Sejdic, Darren Svirskis
Ha, H. T. T., Leal-Ortiz, S., Lalwani, K., Kiyonaka, S., Hamachi, I., Mysore, S. P., ... Kim, S. A. (2018). Shank and Zinc Mediate an AMPA Receptor Subunit Switch in Developing Neurons. FRONTIERS IN MOLECULAR NEUROSCIENCE, 1110.3389/fnmol.2018.00405
Fourie, C., Vyas, Y., Lee, K., Jung, Y., Garner, C. C., & Montgomery, J. M. (2018). Dietary Zinc Supplementation Prevents Autism Related Behaviors and Striatal Synaptic Dysfunction in Shank3 Exon 13-16 Mutant Mice. FRONTIERS IN CELLULAR NEUROSCIENCE, 1210.3389/fncel.2018.00374
Other University of Auckland co-authors: Kevin Lee
Ambroziak, W., Fourie, C., & Montgomery, J. M. (2018). SAP97-mediated rescue of NMDA receptor surface distribution in a neuronal model of Huntington's disease. Hippocampus, 28 (10), 707-723. 10.1002/hipo.22995
Hoggard, M., Vesty, A., Wong, G., Montgomery, J. M., Fourie, C., Douglas, R. G., ... Taylor, M. W. (2018). Characterizing the Human Mycobiota: A Comparison of Small Subunit rRNA, ITS1, ITS2, and Large Subunit rRNA Genomic Targets. FRONTIERS IN MICROBIOLOGY, 910.3389/fmicb.2018.02208
Other University of Auckland co-authors: Mike Taylor, Richard Douglas, Kristi Biswas, Mark Taylor
Ashton, J. L., Burton, R. A. B., Bub, G., Smaill, B. H., & Montgomery, J. M. (2018). Synaptic Plasticity in Cardiac Innervation and Its Potential Role in Atrial Fibrillation. Frontiers in physiology, 910.3389/fphys.2018.00240
Other University of Auckland co-authors: Bruce Smaill, Jesse Ashton
Aqrawe, Z., Patel, N., Montgomery, J., Travas-Sejdic, J., & Svirskis, D. (1/7/2017). Microelectrode modification with macroporous PEDOT/PSS to enhance neuronal recording and stimulation. Poster presented at The 39th Annual International Conference of the IEEE Engineering in Medicine& Biology Society, Jeju, Korea.
Other University of Auckland co-authors: Zaid Aqrawe, Nitish Patel, Jadranka Travas-Sejdic, Darren Svirskis
Goodman, L., Baddeley, D., Ambroziak, W., Waites, C. L., Garner, C. C., Soeller, C., & Montgomery, J. M. (2017). N-terminal SAP97 isoforms differentially regulate synaptic structure and postsynaptic surface pools of AMPA receptors. Hippocampus, 27 (6), 668-682. 10.1002/hipo.22723
URL: http://hdl.handle.net/2292/36074
Other University of Auckland co-authors: David Baddeley, Lucy Goodman