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Dr Kathy Grace Mountjoy
BSc(Hons), PhD
Biography
Dr Kathy Mountjoy is the principal investigator of the Molecular Neuroendocrinology Laboratory in the Department of Physiology and is also a member of the Department of Molecular Medicine and Pathology, a Principal Investigator in the Centre for Brain Research, and an Associate Investigator in the Maurice Wilkins Centre.
Three years post doctoral training were spent at the Harvard Medical School, Beth Israel Hospital, Boston, MA working with Professor Jeffrey Flier and a further three years at The Vollum Institute for Advanced Biomedical Research, The Oregon Health Sciences University, Portland, Oregon working with Dr Roger Cone.
After returning to Auckland in 1993 her research has concentrated on understanding physiological roles for endogenous melanocortin peptides and how they signal through melanocortin receptors with a particular focus on roles in energy homeostasis.
Research | Current
Research interests
- Endocrinology
- Neuroendocrinology
- Physiology
- Cell Signalling
- Molecular Biology
- Neuroscience
- Biochemistry
- Mouse Genetics
Active Research Collaborations
Dr Gus Grey, Department of Physiology, University of Auckland
Professor Joel Elmquist, University of Texas Southwestern Medical Center, Dallas, TX
Professor Brad Lowell, Harvard University, Boston, MA
Recent Publications
Kumar, S. S., Ward, M. -L., & Mountjoy, K. G. (2021). Quantitative high-throughput assay to measure MC4R-induced intracellular calcium.. Journal of molecular endocrinology, 66(4), 285-297. doi:10.1530/jme-20-0285
Mountjoy, K. G. (2021) ELISA versus LUMINEX assay for measuring mouse metabolic hormones and cytokines: sharing the lessons I have learned, Journal of Immunoassay and Immunochemistry, 42:2, 154-173, DOI: 10.1080/15321819.2020.1838924
Shome, A., McGregor, A., Cavadino, A., & Mountjoy, K. G. (2020). Central administration of β-MSH reduces body weight in obese male Pomctm1/tm1mice.. Biochimica et biophysica acta. General subjects, 1864(10), 129673. doi:10.1016/j.bbagen.2020.129673
Caruso, V., Chai, B. -X., Clark, A. J. L., Cone, R. D., Eberle, A. N., Farooqi, S., . . . Wikberg, J. E. S. (2019). Melanocortin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE, 2019(4). doi:10.2218/gtopdb/f38/2019.4
Hubbard, K., Shome, A., Sun, B., Pontré, B., McGregor, A., & Mountjoy, K. G. (2019). Chronic High-Fat Diet Exacerbates Sexually Dimorphic Pomctm1/tm1 Mouse Obesity.. Endocrinology, 160(5), 1081-1096. doi:10.1210/en.2018-00924
Mountjoy, K. G., Caron, A., Hubbard, K., Shome, A., Grey, A. C., Sun, B., . . . Elmquist, J. K. (2018). Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance.. Molecular metabolism, 9, 207-216. doi:10.1016/j.molmet.2017.11.008
Mountjoy, K. G. (2015). Pro-Opiomelanocortin (POMC) Neurones, POMC-Derived Peptides, Melanocortin Receptors and Obesity: How Understanding of this System has Changed Over the Last Decade.. Journal of neuroendocrinology, 27(6), 406-418. doi:10.1111/jne.12285
Kay, E. I., Botha, R., Montgomery, J. M., & Mountjoy, K. G. (2015). hMRAPα, but Not hMRAP2, Enhances hMC4R Constitutive Activity in HEK293 Cells and This Is Not Dependent on hMRAPα Induced Changes in hMC4R Complex N-linked Glycosylation.. PloS one, 10(10), e0140320. doi:10.1371/journal.pone.0140320
Teaching | Current
Course Co-ordinator for MedSci 732
Course Co-ordinator for MedSCi 312
Postgraduate supervision
Doctorate
Shree Kumar
Areas of expertise
- Molecular biology
- Endocrinology
- Neuroendocrinology
- Cell culture
- Cell signaling assays
- ELISA
- Western blotting
- In situ hybridisation
- Digital Droplet PCR
- Immunohistochemistry
- Mouse physiology
- Mouse genetics
Committees/Professional groups/Services
- American Endocrine Society
- Australian Endocrine Society
- New Zealand Endocrine Society
- New Zealand Physiological Society
- Neuroscience Society
- American Association for the Advancement of Science
- American Neuroendocrine Society
Selected publications and creative works (Research Outputs)
- Tercel, M., Marnane, R. N., Tatnell, M. A., Stevenson, R. J., Halim, A., Lu, G. L., ... Wilson, W. R. (2013). An indoline-derived compound that markedly reduces mouse body weight. International Journal of Obesity, 37, 685-692. 10.1038/ijo.2012.97
Other University of Auckland co-authors: Bill Denny, William Wilson, Moana Tercel, Leon Lu, Rebecca Marnane - Tercel, M., Stevenson, R. J., Lu, G. L., Stribbling, S. M., Wilson, W. R., Tatnell, M. A., ... Denny, W. A. (2012). Weight loss effects of quaternary salts of 5-amino-1-(chloromethyl)-1,2- dihydro-3H-benz[e]indoles; Structure-activity relationships. Bioorganic and Medicinal Chemistry, 20 (2), 734-749. 10.1016/j.bmc.2011.12.007
Other University of Auckland co-authors: Bill Denny, William Wilson, Moana Tercel, Leon Lu
Identifiers
Contact details
- +64 9 923 6447
- +64.9.923.6447
- k.mountjoy@auckland.ac.nz
- kmou002@aucklanduni.ac.nz
- Media Contact
Primary office location
M&HS BUILDING 502 - Bldg 502
Level 5, Room 501B
85 PARK RD
NZL
AUCKLAND 1023
New Zealand