Dr Melissa Michelle Cadelis

BSc (Hons) PhD. University of Auckland

Biography

Education

2011 BSc (specialising in Medicinal Chemistry), University of Auckland, NZ

2012 BSc (Honours) with First Class Honours in Medicinal Chemistry, University of Auckland, NZ

2017 PhD (Chemistry), University of Auckland, NZ

 

Previous Appointments

2016 Post-Doctoral Research Fellow in the School of Chemical Sciences (University of Auckland)

Current Appointments

2017-current Post-Doctoral Research Fellow in the Department of Molecular Medicine and Pathology (University of Auckland) 

Research | Current

Current research interests are directed towards the:

  • Discovery of new antibacterial compounds from New Zealand fungi
  • Development of new class of antibacterial compounds against MRSA
  • Development of IDO1 inhibitors as anticancer agents

Teaching | Current

CHEM 92F

CHEM 110

CHEM 150

CHEM 398

Postgraduate supervision

Steven A. Li - PhD student (co-supervisor)

Roy Y. Lai - PhD student (co-supervisor)

Kenneth Sue - PhD student (advisor)

Liam Edmeades - PhD student (advisor)

Dan Chen - Masters student (co-supervisor)

Judy Zheng - Masters student (co-supervisor)

Daniel Park -  Honours student (co-supervisor)

Evangelene Gill - Honours student (co-supervisor)

Areas of expertise

Antibacterial drug discovery

Natural product isolation

Bioactive small molecule synthesis

Committees/Professional groups/Services

Co-chair - Faculty of Science Research Fellow Society 

Reviewer Board - Antibiotics

Reviewer Board - Microorganisms

Selected publications and creative works (Research Outputs)

As of 29 October 2020 there will be no automatic updating of 'selected publications and creative works' from Research Outputs. Please continue to keep your Research Outputs profile up to date.
  • Cadelis, M. M., Pike, E. I. W., Kang, W., Wu, Z., Bourguet-Kondracki, M.-L., Blanchet, M., ... Copp, B. R. (2019). Exploration of the antibiotic potentiating activity of indolglyoxylpolyamines. European journal of medicinal chemistry, 18310.1016/j.ejmech.2019.111708
    Other University of Auckland co-authors: Brent Copp, Zimei Wu
  • Li, S. A., Cadelis, M. M., Sue, K., Blanchet, M., Vidal, N., Brunel, J. M., ... Copp, B. R. (2019). 6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers. Bioorganic & medicinal chemistry, 27 (10), 2090-2099. 10.1016/j.bmc.2019.04.004
    Other University of Auckland co-authors: Brent Copp, Steven Li, Kenneth Sue
  • Fong, H. K. H., Cadelis, M. M., Brunel, J. M., Bourguet-Kondracki, M.-L., Barker, D., & Copp, B. R. (2018). Alaninyl variants of the marine natural product halocyamine A and their antibacterial properties. TETRAHEDRON, 74 (48), 6929-6938. 10.1016/j.tet.2018.10.021
    Other University of Auckland co-authors: Brent Copp, David Barker
  • Harris, E. M., Strope, J. D., Beedie, S. L., Huang, P. A., Goey, A. K. L., Cook, K. M., ... Copp, B. R. (2018). Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models. Marine drugs, 16 (7).10.3390/md16070241
    Other University of Auckland co-authors: Brent Copp
  • Cadelis, M. M., & Copp, B. R. (2018). Investigation of the electrophilic reactivity of the biologically active marine sesquiterpenoid onchidal and model compounds. Beilstein journal of organic chemistry, 14, 2229-2235. 10.3762/bjoc.14.197
    Other University of Auckland co-authors: Brent Copp
  • Tempone, A. G., Ferreira, D. D., Lima, M. L., Costa Silva, T. A., Borborema, S. E. T., Reimão JQ, ... Wynne, G. M. (2017). Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi. European Journal of Medicinal Chemistry, 139, 947-960. 10.1016/j.ejmech.2017.08.055
    Other University of Auckland co-authors: Brent Copp
  • Cadelis, M. M., Bourguet-Kondracki, M. L., Dubois, J., Kaiser, M., Brunel, J. M., Barker, D., & Copp, B. R. (2017). Structure-activity relationship studies on thiaplidiaquinones A and B as novel inhibitors of Plasmodium falciparum and farnesyltransferase. Bioorganic & Medicinal Chemistry, 25 (16), 4433-4443. 10.1016/j.bmc.2017.06.029
    URL: http://hdl.handle.net/2292/36045
    Other University of Auckland co-authors: David Barker, Brent Copp
  • Lam, C. F., Cadelis, M. M., & Copp, B. R. (2017). Exploration of the influence of spiro-dienone moiety on biological activity of the cytotoxic marine alkaloid discorhabdin P. Tetrahedron, 73 (32), 4779-4785. 10.1016/j.tet.2017.06.057
    Other University of Auckland co-authors: Brent Copp

Identifiers

Contact details

Primary office location

SCIENCE CENTRE 301 - Bldg 301
Level 6, Room 627A
23 SYMONDS ST
AUCKLAND CENTRAL
AUCKLAND 1010
New Zealand

Web links