Dr Melissa Michelle Cadelis

BSc (Hons) PhD. University of Auckland

Biography

Education

2011 BSc (specialising in Medicinal Chemistry), University of Auckland, NZ

2012 BSc (Honours) with First Class Honours in Medicinal Chemistry, University of Auckland, NZ

2016 PhD (Chemistry), University of Auckland, NZ

 

Previous Appointments

2016 Post-Doctoral Research Fellow in the School of Chemical Sciences (University of Auckland) with Prof Brent Copp 

Current Appointments

2017-current Post-Doctoral Research Fellow in the Department of Molecular Medicine and Pathology (University of Auckland) with A/P Siouxsie Wiles and Prof Brent Copp

Selected publications and creative works (Research Outputs)

  • Li, S. A., Cadelis, M. M., Sue, K., Blanchet, M., Vidal, N., Brunel, J. M., ... Copp, B. R. (2019). 6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers. Bioorganic & medicinal chemistry, 27 (10), 2090-2099. 10.1016/j.bmc.2019.04.004
    Other University of Auckland co-authors: Brent Copp
  • Fong, H. K. H., Cadelis, M. M., Brunel, J. M., Bourguet-Kondracki, M.-L., Barker, D., & Copp, B. R. (2018). Alaninyl variants of the marine natural product halocyamine A and their antibacterial properties. TETRAHEDRON, 74 (48), 6929-6938. 10.1016/j.tet.2018.10.021
    Other University of Auckland co-authors: Brent Copp, David Barker
  • Harris, E. M., Strope, J. D., Beedie, S. L., Huang, P. A., Goey, A. K. L., Cook, K. M., ... Copp, B. R. (2018). Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models. Marine drugs, 16 (7).10.3390/md16070241
    Other University of Auckland co-authors: Brent Copp
  • Cadelis, M. M., & Copp, B. R. (2018). Investigation of the electrophilic reactivity of the biologically active marine sesquiterpenoid onchidal and model compounds. Beilstein journal of organic chemistry, 14, 2229-2235. 10.3762/bjoc.14.197
    Other University of Auckland co-authors: Brent Copp
  • Tempone, A. G., Ferreira, D. D., Lima, M. L., Costa Silva, T. A., Borborema, S. E. T., Reimão JQ, ... Wynne, G. M. (2017). Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi. European Journal of Medicinal Chemistry, 139, 947-960. 10.1016/j.ejmech.2017.08.055
    URL: http://hdl.handle.net/2292/44239
    Other University of Auckland co-authors: Brent Copp
  • Cadelis, M. M., Bourguet-Kondracki, M. L., Dubois, J., Kaiser, M., Brunel, J. M., Barker, D., & Copp, B. R. (2017). Structure-activity relationship studies on thiaplidiaquinones A and B as novel inhibitors of Plasmodium falciparum and farnesyltransferase. Bioorganic & Medicinal Chemistry, 25 (16), 4433-4443. 10.1016/j.bmc.2017.06.029
    URL: http://hdl.handle.net/2292/36045
    Other University of Auckland co-authors: David Barker, Brent Copp
  • Lam, C. F., Cadelis, M. M., & Copp, B. R. (2017). Exploration of the influence of spiro-dienone moiety on biological activity of the cytotoxic marine alkaloid discorhabdin P. Tetrahedron, 73 (32), 4779-4785. 10.1016/j.tet.2017.06.057
    URL: http://hdl.handle.net/2292/39678
    Other University of Auckland co-authors: Brent Copp
  • Cadelis, M. M., Khalil, I. M., Harper, J. L., Shaw, L., Dubois, J., Valentin, A., ... Copp, B. R. (2016). Structure-activity relationships of bioactive marine natural products leading to the identification of more potent non-natural analogues - the meroterpenoids, thiaplidiaquinones A and B. Paper presented at 9th Joint Meeting of AFERP, ASP, GA, JSP, PSE & SIF, Copenhagen, Denmark. 24 July - 27 July 2016. Planta Medica. (pp. 2). 10.1055/s-0036-1596124
    Other University of Auckland co-authors: David Barker, Brent Copp

Contact details

Primary office location

SCIENCE CENTRE 301 - Bldg 301
Level B, Room B006
23 SYMONDS ST
AUCKLAND 1010
New Zealand