Dr Mark Linton Trew

BE PhD

Senior Research Fellow

Biography

Mark Trew attained a Bachelor of Engineering in Engineering Science in 1992 and a PhD Engineering Science in 1999, both from the University of Auckland. He is currently a Senior Research Fellow at the Auckland Bioengineering Institute.

From 1999 to 2001 Mark worked as a Research Engineer for Auckland UniServices on contract to PB Power Genzel NZ and Japan Petroleum Exploration Corporation, devising methods for predicting geothermal tracer chemical behaviour at high-temperatures. He joined the Bioengineering Group in 2001 and from 1999 to 2003 he also held part-time lecturing appointments in the Department of Engineering Science.

Research | Current

Mark constructs computer models and analysis tools for interpreting and understanding detailed images of cardiac tissue and cardiac electrical activity. His research interests include:

Cardiac electrical rhythm,
Tissue response to electric shock,
Computational techniques for simulating cardiac electrical behaviour,
Mathematical descriptions of cardiac tissue structure.

Project links

Selected publications and creative works (Research Outputs)

Trew, M. L., Engelman, Z. J., Caldwell, B. J., Lever, N. A., LeGrice, I. J., & Smaill, B. H. (2019). Cardiac intramural electrical mapping reveals focal delays but no conduction velocity slowing in the peri-infarct region. American journal of physiology. Heart and circulatory physiology, 317 (4), H743-H753. 10.1152/ajpheart.00154.2019
Other University of Auckland co-authors: Bruce Smaill, Nigel Lever, Ian LeGrice
Ashton, J. L., Trew, M. L., LeGrice, I. J., Paterson, D. J., Paton, J. F., Gillis, A. M., & Smaill, B. H. (2019). Shift of leading pacemaker site during reflex vagal stimulation and altered electrical source-to-sink balance. The Journal of physiology, 597 (13), 3297-3313. 10.1113/jp276876
Other University of Auckland co-authors: Jesse Ashton, Julian Paton, Ian LeGrice, Bruce Smaill
Ai, W., Patel, N. D., Roop, P., Malik, A., & Trew, M. L. (2019). Cardiac Electrical Modeling for Closed-loop Validation of Implantable Devices. IEEE Transactions on Biomedical Engineering10.1109/TBME.2019.2917212
Other University of Auckland co-authors: Weiwei Ai, Nitish Patel, Partha Roop, Avinash Malik
Ashton, J. L., Sands, G. B., Khwaounjoo, P., Ramlugun, G. S., Trew, M. L., Walton, R. D., ... Smaill, B. H. (2019). Cellular Electrical Coupling in the Human Heart: An Image-Based Analysis Pipeline. Paper presented at Heart Rhythm 40th Scientific Sessions, San Francisco, CA. 8 May - 11 May 2019. Heart Rhythm. 10.1016/j.hrthm.2019.04.020
Other University of Auckland co-authors: Gregory Sands, Jesse Ashton, David Baddeley, Bruce Smaill
Peng, T., Trew, M. L., & Malik, A. (2019). Predictive modeling of drug effects on electrocardiograms. Computers in biology and medicine, 108, 332-344. 10.1016/j.compbiomed.2019.03.027
Other University of Auckland co-authors: Avinash Malik, Tommy Peng
Ai, W., Patel, N. D., Roop, P., Malik, A., & Trew, M. L. (2019). Closing the loop: Validation of implantable cardiac devices with computational heart models. IEEE Journal of Biomedical and Health Informatics10.1109/JBHI.2019.2947007
Other University of Auckland co-authors: Weiwei Ai, Nitish Patel, Partha Roop, Avinash Malik
Haliot, K., Magat, J., Ozenne, V., Abell, E., Dubes, V., Bear, L., ... Quesson, B. (2019). 3D High Resolution Imaging of Human Heart for Visualization of the Cardiac Structure. Paper presented at 10th International Conference on Functional Imaging and Modeling of the Heart (FIMH), Bordeaux, FRANCE. 6 June - 8 June 2019. FUNCTIONAL IMAGING AND MODELING OF THE HEART, FIMH 2019. (pp. 12). 10.1007/978-3-030-21949-9_22
Sehgal, S., Patel, N. D., Malik, A., Roop, P. S., & Trew, M. L. (2019). Resonant model-A new paradigm for modeling an action potential of biological cells. PloS one, 14 (5)10.1371/journal.pone.0216999
Other University of Auckland co-authors: Nitish Patel, Avinash Malik, Partha Roop, Sucheta Sehgal