Dr Mark Linton Trew

BE PhD

Senior Research Fellow

Biography

Mark Trew attained a Bachelor of Engineering in Engineering Science in 1992 and a PhD Engineering Science in 1999, both from the University of Auckland. He is currently a Senior Research Fellow at the Auckland Bioengineering Institute.

From 1999 to 2001 Mark worked as a Research Engineer for Auckland UniServices on contract to PB Power Genzel NZ and Japan Petroleum Exploration Corporation, devising methods for predicting geothermal tracer chemical behaviour at high-temperatures. He joined the Bioengineering Group in 2001 and from 1999 to 2003 he also held part-time lecturing appointments in the Department of Engineering Science.

Research | Current

Mark constructs computer models and analysis tools for interpreting and understanding detailed images of cardiac tissue and cardiac electrical activity. His research interests include:

Cardiac electrical rhythm,
Tissue response to electric shock,
Computational techniques for simulating cardiac electrical behaviour,
Mathematical descriptions of cardiac tissue structure.

Project links

Selected publications and creative works (Research Outputs)

Ashton, J. L., Trew, M. L., LeGrice, I. J., Paterson, D. J., Paton, J. F., Gillis, A. M., & Smaill, B. H. (2019). Shift of leading pacemaker site during reflex vagal stimulation and altered electrical source-to-sink balance. The Journal of physiology10.1113/jp276876
Other University of Auckland co-authors: Jesse Ashton, Julian Paton, Ian LeGrice, Bruce Smaill
Ashton, J. L., Sands, G. B., Khwaounjoo, P., Ramlugun, G. S., Trew, M. L., Walton, R. D., ... Smaill, B. H. (2019). Cellular Electrical Coupling in the Human Heart: An Image-Based Analysis Pipeline. Paper presented at Heart Rhythm 40th Scientific Sessions, San Francisco, CA. 8 May - 11 May 2019. Heart Rhythm. 10.1016/j.hrthm.2019.04.020
Other University of Auckland co-authors: Gregory Sands, Jesse Ashton, Girish Ramlugun, David Baddeley
Peng, T., Trew, M. L., & Malik, A. (2019). Predictive modeling of drug effects on electrocardiograms. Computers in biology and medicine, 108, 332-344. 10.1016/j.compbiomed.2019.03.027
Other University of Auckland co-authors: Avinash Malik, Tommy Peng
Shalbaf, F., Lovell, N. H., Dokos, S., Trew, M., & Vaghefi, E. (2019). Foveal eccentricity can influence activation threshold in subretinal electrical stimulation. BIOMEDICAL PHYSICS & ENGINEERING EXPRESS, 5 (3)10.1088/2057-1976/ab0b85
URL: http://hdl.handle.net/2292/47135
Other University of Auckland co-authors: Ehsan Vaghefi
Haliot, K., Magat, J., Ozenne, V., Abell, E., Dubes, V., Bear, L., ... Quesson, B. (2019). 3D High Resolution Imaging of Human Heart for Visualization of the Cardiac Structure. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 10.1007/978-3-030-21949-9_22
Sehgal, S., Patel, N. D., Malik, A., Roop, P. S., & Trew, M. L. (2019). Resonant model-A new paradigm for modeling an action potential of biological cells. PloS one, 14 (5)10.1371/journal.pone.0216999
Other University of Auckland co-authors: Nitish Patel, Avinash Malik, Partha Roop, Sucheta Sehgal
Yip, E., Andalam, S., Roop, P. S., Malik, A., Trew, M. L., Ai, W., & Patel, N. (2018). Towards the Emulation of the Cardiac Conduction System for Pacemaker Validation. ACM TRANSACTIONS ON CYBER-PHYSICAL SYSTEMS, 2 (4)10.1145/3134845
Other University of Auckland co-authors: Avinash Malik, Partha Roop
Andalam, S., Roop, P., Malik, A., & Trew, M. (2018). Rethinking the validation process for medical devices: A cardiac pacemaker case study. Proceedings - 2018 IEEE 21st International Symposium on Real-Time Computing, ISORC 2018. 10.1109/ISORC.2018.00027
Other University of Auckland co-authors: Avinash Malik, Partha Roop