Dr Mark Linton Trew


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Senior Research Fellow


Mark Trew attained a Bachelor of Engineering in Engineering Science in 1992 and a PhD Engineering Science in 1999, both from the University of Auckland. He is currently a Senior Research Fellow at the Auckland Bioengineering Institute.

From 1999 to 2001 Mark worked as a Research Engineer for Auckland UniServices on contract to PB Power Genzel NZ and Japan Petroleum Exploration Corporation, devising methods for predicting geothermal tracer chemical behaviour at high-temperatures. He joined the Bioengineering Group in 2001 and from 1999 to 2003 he also held part-time lecturing appointments in the Department of Engineering Science.

Research | Current

Mark constructs computer models and analysis tools for interpreting and understanding detailed images of cardiac tissue and cardiac electrical activity. His research interests include:

  • Cardiac electrical rhythm,
  • Tissue response to electric shock,
  • Computational techniques for simulating cardiac electrical behaviour,
  • Mathematical descriptions of cardiac tissue structure.

Project links

Selected publications and creative works (Research Outputs)

  • Trew, M. L., Engelman, Z. J., Caldwell, B. J., Lever, N. A., LeGrice, I. J., & Smaill, B. H. (2019). Cardiac intramural electrical mapping reveals focal delays but no conduction velocity slowing in the peri-infarct region. American journal of physiology. Heart and circulatory physiology, 317 (4), H743-H753. 10.1152/ajpheart.00154.2019
    Other University of Auckland co-authors: Bruce Smaill, Nigel Lever, Ian LeGrice
  • Ashton, J. L., Trew, M. L., LeGrice, I. J., Paterson, D. J., Paton, J. F., Gillis, A. M., & Smaill, B. H. (2019). Shift of leading pacemaker site during reflex vagal stimulation and altered electrical source-to-sink balance. The Journal of physiology, 597 (13), 3297-3313. 10.1113/jp276876
    Other University of Auckland co-authors: Jesse Ashton, Julian Paton, Ian LeGrice, Bruce Smaill
  • Ai, W., Patel, N. D., Roop, P., Malik, A., & Trew, M. L. (2019). Cardiac Electrical Modeling for Closed-loop Validation of Implantable Devices. IEEE Transactions on Biomedical Engineering10.1109/TBME.2019.2917212
    Other University of Auckland co-authors: Weiwei Ai, Nitish Patel, Partha Roop, Avinash Malik
  • Ashton, J. L., Sands, G. B., Khwaounjoo, P., Ramlugun, G. S., Trew, M. L., Walton, R. D., ... Smaill, B. H. (2019). Cellular Electrical Coupling in the Human Heart: An Image-Based Analysis Pipeline. Paper presented at Heart Rhythm 40th Scientific Sessions, San Francisco, CA. 8 May - 11 May 2019. Heart Rhythm. 10.1016/j.hrthm.2019.04.020
    Other University of Auckland co-authors: Gregory Sands, Jesse Ashton, David Baddeley, Bruce Smaill
  • Peng, T., Trew, M. L., & Malik, A. (2019). Predictive modeling of drug effects on electrocardiograms. Computers in biology and medicine, 108, 332-344. 10.1016/j.compbiomed.2019.03.027
    Other University of Auckland co-authors: Avinash Malik, Tommy Peng
  • Ai, W., Patel, N. D., Roop, P., Malik, A., & Trew, M. L. (2019). Closing the loop: Validation of implantable cardiac devices with computational heart models. IEEE Journal of Biomedical and Health Informatics10.1109/JBHI.2019.2947007
    Other University of Auckland co-authors: Weiwei Ai, Nitish Patel, Partha Roop, Avinash Malik
  • Haliot, K., Magat, J., Ozenne, V., Abell, E., Dubes, V., Bear, L., ... Quesson, B. (2019). 3D High Resolution Imaging of Human Heart for Visualization of the Cardiac Structure. Paper presented at 10th International Conference on Functional Imaging and Modeling of the Heart (FIMH), Bordeaux, FRANCE. 6 June - 8 June 2019. FUNCTIONAL IMAGING AND MODELING OF THE HEART, FIMH 2019. (pp. 12). 10.1007/978-3-030-21949-9_22
  • Sehgal, S., Patel, N. D., Malik, A., Roop, P. S., & Trew, M. L. (2019). Resonant model-A new paradigm for modeling an action potential of biological cells. PloS one, 14 (5)10.1371/journal.pone.0216999
    Other University of Auckland co-authors: Nitish Patel, Avinash Malik, Partha Roop, Sucheta Sehgal


Contact details

Primary office location

Level 6, Room 637
New Zealand

Web links