Professor Mark Hedley Vickers

BSc, MSc (Hons), PhD

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Associate Director Academic

Biography

Mark's primary interest is in the developmental origins of health and disease with a particular focus on the association between poor maternal nutrition and the development of obesity and type 2 diabetes in offspring.  He also has an interest in therapies aimed at reversing the metabolic disturbances that result from a suboptimal early life environment.

Collaborations:

  • University of Cambridge
  • University of Southampton
  • Singapore Institute for Clinical Sciences and National University of Singapore
  • University of Western Australia
  • McGill University, Montreal, Canada

Personal quote:

“Few other aspects of nutrient supply and metabolism are of greater biological importance than the feeding of mothers during pregnancy and lactation. Our research aims to develop platforms to examine nutrition during these critical windows and optimize the health of mothers and offspring to reduce risk of adult diseases such as obesity and diabetes in adult life.”

 

Research | Current

  • Developmental origins of health and disease
  • Maternal and infant nutrition, obesity, metabolic syndrome, type 2 diabetes

Major grant funding:

  • Health Research Council of NZ (HRC)
  • Gravida: National Centre for Growth and Development
  • Marsden Fund
  • Ministry of Business, Innovation and Employment (MBIE)
  • Auckland Medical Research Foundation

 

Teaching | Current

  • Developmental programming, Stage 3 Physiology
  • MedSci courses 304, 729, 734

Areas of expertise

Maternal nutrition, developmental programming, obesity, metabolic syndrome, pregnancy, diabetes, nutrition, fetal growth

Committees/Professional groups/Services

Associate Dean Research (Liggins Institute)

UARC

Masters Advisory Committee

Postgraduate Studies Committee

Ethics Committee

NZ Representative, DOHaD Society

 

Selected publications and creative works (Research Outputs)

  • Nyaga, D. M., Vickers, M. H., Jefferies, C., Perry, J. K., & O'Sullivan JM (2018). The genetic architecture of type 1 diabetes mellitus. Molecular and cellular endocrinology, 477, 70-80. 10.1016/j.mce.2018.06.002
    Other University of Auckland co-authors: Jo Perry, Justin O'Sullivan
  • Jacobson, E. C., Perry, J. K., Long, D. S., Olins, A. L., Olins, D. E., Wright, B. E., ... O'Sullivan JM (2018). Migration through a small pore disrupts inactive chromatin organization in neutrophil-like cells. BMC biology, 16 (1)10.1186/s12915-018-0608-2
    Other University of Auckland co-authors: Justin O'Sullivan
  • Nyaga, D. M., Vickers, M. H., Jefferies, C., Perry, J. K., & O'Sullivan JM (2018). Type 1 Diabetes Mellitus-Associated Genetic Variants Contribute to Overlapping Immune Regulatory Networks. FRONTIERS IN GENETICS, 910.3389/fgene.2018.00535
    Other University of Auckland co-authors: Jo Perry, Justin O'Sullivan
  • Jacobson, E., Perry, J., Vickers, M., Olins, A., Olins, D., & O'Sullivan J (2018). TNF-α differentially regulates cell cycle genes in promyelocytic and granulocytic HL-60/S4 cells. 10.1101/471789
    Other University of Auckland co-authors: Jo Perry
  • Mills, V., Plows, J. F., Zhao, H., Oyston, C., Vickers, M. H., Baker, P. N., & Stanley, J. L. (2018). Effect of sildenafil citrate treatment in the eNOS knockout mouse model of fetal growth restriction on long-term cardiometabolic outcomes in male offspring. Pharmacological research, 137, 122-134. 10.1016/j.phrs.2018.09.023
    Other University of Auckland co-authors: Philip Baker
  • Plows, J. F., Stanley, J. L., Baker, P. N., Reynolds, C. M., & Vickers, M. H. (2018). The Pathophysiology of Gestational Diabetes Mellitus. International journal of molecular sciences, 19 (11).10.3390/ijms19113342
    Other University of Auckland co-authors: Clare Reynolds, Philip Baker
  • Galante, L., Milan, A. M., Reynolds, C. M., Cameron-Smith, D., Vickers, M. H., & Pundir, S. (2018). Sex-Specific Human Milk Composition: The Role of Infant Sex in Determining Early Life Nutrition. Nutrients, 10 (9).10.3390/nu10091194
    Other University of Auckland co-authors: David Cameron-Smith, Laura Galante, Amber Milan, Clare Reynolds, Shikha Pundir
  • Jacobson, E., Perry, J., Long, D., Olins, A., Olins, D., Wright, B., ... O'Sullivan J (2018). Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells. 10.1101/339085
    Other University of Auckland co-authors: Jo Perry, Bryon Wright

Identifiers

Contact details

Primary office location

M&HS BUILDING 505 - Bldg 505
Level 2, Room 202G
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand

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