Dr Jacelyn Mei San Loh

PhD in Molecular Biology

Biography

I am a Senior Research Fellow and member of the Infection and Immunity cluster in the Department of Molecular Medicine and Pathology. Prior to this appointment, I was a postdoctoral fellow at the University of Geneva, Switzerland, with a research focus on Glioma immunotherapy. After returning to NZ, I worked at Plant and Food Research studying the immune benefits of "superfruits".

Research | Current

Streptococcus pyogenes or Group A streptococcus (GAS) is a gram positive bacterium that can cause a wide variety of diseases ranging from pharyngitis and tonsillitis to severe invasive diseases, such as necrotizing fasciitis (“flesh eating disease”) and streptococcal toxic shock syndrome. Streptococcal sequela, which includes glomerulonephritis and acute rheumatic fever, are often complications of streptococcal infection and remain a significant problem in NZ. My Present research into the pili (very thin, hair-like structures protruding from the surface of the bacterial cell) of GAS investigates the potential use of the pilus as a target for vaccine development. My results have shown that pili proteins are highly immunogenic and can elicit strong antibody responses in mice and rabbits. My work also focuses on the development of bioluminescent GAS strains for high-throughput monitoring of immune responses, as well as development of mouse infection models for vaccination studies.

Teaching | Current

MedSci705

Postgraduate supervision

Samuel Blanchett (PhD)

Kar Yan Soh (PhD)

Haniyeh Aghababa (PhD)

Tiger Aspell (PhD)

Distinctions/Honours

National Heart Foundation Research Fellow

Areas of expertise

Microbiology and Immunology

Committees/Professional groups/Services

Committee member of the FMHS Post-doc Society

Member of the Australasian Society for Immunology

Member of the NZ Microbiological Society

Selected publications and creative works (Research Outputs)

Identifiers

Contact details

Office hours

8am-4pm

Primary office location

M&HS BUILDING 502 - Bldg 502
Level 3, Room 301
85 PARK RD
NZL
AUCKLAND 1023
New Zealand

Web links