Professor Nicola Dalbeth
MBChB MD FRACP
Nicola Dalbeth is an academic rheumatologist who leads a clinical and laboratory programme of research in gout, an inflammatory arthritis of major significance to Aotearoa New Zealand. Her work focuses on understanding the impact and mechanisms of disease in gout.
She has been lead investigator in both commercial and investigator-initiated clinical trials in gout. She is a founding member of the Counties Manukau District Health Board Māori Gout Action Group. She chairs the Atlas of Healthcare Variation Gout Expert Advisory Group, and Australia and New Zealand Gout Special Interest Forum. She was the Lead Clinical Advisor for the Gout Clinical Pathways (Greater Auckland Integrated Healthcare Network) and the national bpac Gout Treatment Guidelines. She has served as an Expert Panel member on the American College of Rheumatology Gout Management Guidelines, and is a steering committee member for the OMERACT gout working group and the ACR/EULAR gout classification project.
Research | Current
Clinical research includes clinical trials, imaging studies (using plain radiographs, MRI and three-dimensional CT modeling) to analyze joint damage, studies to investigate the functional impact of gout, and validation of outcome measures in gout. The laboratory work in the Auckland Bone and Joint Research Laboratory involves investigating the cellular and molecular mechanisms of inflammation and joint damage in gout.
Selected publications and creative works (Research Outputs)
- Weinman, J., Graham, S., Canfield, M., Kleinstäuber M, Perera, A. I., Dalbeth, N., & Petrie, K. J. (2018). The Intentional Non-Adherence Scale (INAS): Initial development and validation. Journal of Psychosomatic Research, 115, 110-116. 10.1016/j.jpsychores.2018.10.010
Other University of Auckland co-authors: Maria Kleinstaeuber
- Stewart, S., Keys, M., Brenton-Rule, A., Aiyer, A., Dalbeth, N., & Rome, K. (2018). Characteristics of footwear worn by people with systemic lupus erythematosus: a comparison with age- and sex-matched healthy controls: a pilot study. Journal of Foot and Ankle Research, 11 (1).10.1186/s13047-018-0280-3
- Hutton, J., Fatima, T., Major, T. J., Topless, R., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2018). Mediation analysis to understand genetic relationships between habitual coffee intake and gout. Arthritis Research & Therapy. 10.1186/s13075-018-1629-5
- Choi, H., Neogi, T., Stamp, L., Dalbeth, N., & Terkeltaub, R. (2018). New Perspectives in Rheumatology: Implications of the Cardiovascular Safety of Febuxostat and Allopurinol in Patients With Gout and Cardiovascular Morbidities Trial and the Associated Food and Drug Administration Public Safety Alert. Arthritis & rheumatology (Hoboken, N.J.), 70 (11), 1702-1709. 10.1002/art.40583
- Kalev-Zylinska, M. L., Hearn, J. I., Rong, J., Zhu, M., Munro, J., Cornish, J., ... Poulsen, R. C. (2018). Altered N-methyl D-aspartate receptor subunit expression causes changes to the circadian clock and cell phenotype in osteoarthritic chondrocytes. Osteoarthritis and cartilage, 26 (11), 1518-1530. 10.1016/j.joca.2018.06.015
Other University of Auckland co-authors: Raewyn Poulsen, Maggie Kalev, James Hearn, Jacob Munro, Jillian Cornish
- Major, T. J., Topless, R. K., Dalbeth, N., & Merriman, T. R. (2018). Evaluation of the diet wide contribution to serum urate levels: meta-analysis of population based cohorts. BMJ (Clinical research ed.), 36310.1136/bmj.k3951
- Neogi, T., & Dalbeth, N. (2018). Patient education and engagement in treat-to-target gout care. Lancet (London, England), 392 (10156), 1379-1381. 10.1016/s0140-6736(18)32415-2
- Stamp, L., Morillon, M. B., Taylor, W. J., Dalbeth, N., Singh, J. A., Lassere, M., & Christensen, R. (2018). Serum urate as surrogate endpoint for flares in people with gout: A systematic review and meta-regression analysis. Seminars in arthritis and rheumatism, 48 (2), 293-301. 10.1016/j.semarthrit.2018.02.009