Professor Nicola Dalbeth
MBChB MD FRACP
Nicola Dalbeth is an academic rheumatologist who leads a clinical and laboratory programme of research in gout, an inflammatory arthritis of major significance to Aotearoa New Zealand. Her work focuses on understanding the impact and mechanisms of disease in gout.
She has been lead investigator in both commercial and investigator-initiated clinical trials in gout. She is a founding member of the Counties Manukau District Health Board Māori Gout Action Group. She chairs the Atlas of Healthcare Variation Gout Expert Advisory Group, and Australia and New Zealand Gout Special Interest Forum. She was the Lead Clinical Advisor for the Gout Clinical Pathways (Greater Auckland Integrated Healthcare Network) and the national bpac Gout Treatment Guidelines. She has served as an Expert Panel member on the American College of Rheumatology Gout Management Guidelines, and is a steering committee member for the OMERACT gout working group and the ACR/EULAR gout classification project.
Research | Current
Clinical research includes clinical trials, imaging studies (using plain radiographs, MRI and three-dimensional CT modeling) to analyze joint damage, studies to investigate the functional impact of gout, and validation of outcome measures in gout. The laboratory work in the Auckland Bone and Joint Research Laboratory involves investigating the cellular and molecular mechanisms of inflammation and joint damage in gout.
Selected publications and creative works (Research Outputs)
- Krishnan, M., Major, T. J., Topless, R. K., Dewes, O., Yu, L., Thompson, J. M. D., ... Dalbeth, N. (2018). Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Māori and Pacific (Polynesian) people living in Aotearoa/New Zealand. Diabetologia, 61 (7), 1603-1613. 10.1007/s00125-018-4623-1
Other University of Auckland co-authors: Ofa Dewes, John Thompson, Lesley McCowan, Andrew Shelling, Rinki Murphy
- Major, T. J., Dalbeth, N., Stahl, E. A., & Merriman, T. R. (2018). An update on the genetics of hyperuricaemia and gout. Nature reviews. Rheumatology, 14 (6), 341-353. 10.1038/s41584-018-0004-x
- Stewart, S., Carroll, M., Brenton-Rule, A., Keys, M., Bell, L., Dalbeth, N., & Rome, K. (2018). Region-specific foot pain and plantar pressure in people with rheumatoid arthritis: A cross-sectional study. Clinical biomechanics (Bristol, Avon), 55, 14-17. 10.1016/j.clinbiomech.2018.04.002
- Fanning, N., Merriman, T. R., Dalbeth, N., & Stamp, L. K. (2018). An association of smoking with serum urate and gout: A health paradox. Seminars in arthritis and rheumatism, 47 (6), 825-842. 10.1016/j.semarthrit.2017.11.004
- Frecklington, M., Dalbeth, N., McNair, P., Gow, P., Williams, A., Carroll, M., & Rome, K. (2018). Footwear interventions for foot pain, function, impairment and disability for people with foot and ankle arthritis: A literature review. Seminars in arthritis and rheumatism, 47 (6), 814-824. 10.1016/j.semarthrit.2017.10.017
- Jordan, K. N., Pennebaker, J. W., Petrie, K. J., & Dalbeth, N. (2018). 'Googling' Gout: Exploring perceptions about gout through a linguistic analysis of online search activities. Arthritis care & research10.1002/acr.23598
- Hall, C. J., Sanderson, L. E., Lawrence, L. M., Pool, B., van der Kroef, M., Ashimbayeva, E., ... Astin, J. W. (2018). Blocking fatty acid-fueled mROS production within macrophages alleviates acute gouty inflammation. The Journal of clinical investigation, 128 (5), 1752-1771. 10.1172/jci94584
Other University of Auckland co-authors: Jonathan Astin, Christopher Hall
- Robinson, P. C., Dalbeth, N., & Donovan, P. (2018). The Cost-effectiveness of Biannual Serum Urate (SU) Monitoring after Reaching Target in Gout: A Health Economic Analysis Comparing SU Monitoring. The Journal of rheumatology, 45 (5), 697-704. 10.3899/jrheum.170199