Professor Nicola Dalbeth
MBChB MD FRACP
Nicola Dalbeth is an academic rheumatologist who leads a clinical and laboratory programme of research in gout, an inflammatory arthritis of major significance to Aotearoa New Zealand. Her work focuses on understanding the impact and mechanisms of disease in gout.
She has been lead investigator in both commercial and investigator-initiated clinical trials in gout. She is a founding member of the Counties Manukau District Health Board Māori Gout Action Group. She chairs the Atlas of Healthcare Variation Gout Expert Advisory Group, and Australia and New Zealand Gout Special Interest Forum. She was the Lead Clinical Advisor for the Gout Clinical Pathways (Greater Auckland Integrated Healthcare Network) and the national bpac Gout Treatment Guidelines. She has served as an Expert Panel member on the American College of Rheumatology Gout Management Guidelines, and is a steering committee member for the OMERACT gout working group and the ACR/EULAR gout classification project.
Research | Current
Clinical research includes clinical trials, imaging studies (using plain radiographs, MRI and three-dimensional CT modeling) to analyze joint damage, studies to investigate the functional impact of gout, and validation of outcome measures in gout. The laboratory work in the Auckland Bone and Joint Research Laboratory involves investigating the cellular and molecular mechanisms of inflammation and joint damage in gout.
Selected publications and creative works (Research Outputs)
- Dalbeth, N. (2017). Febuxostat reduces synovitis in early gout. NATURE REVIEWS RHEUMATOLOGY, 13 (12)
- Derksen, C., Serlachius, A., Petrie, K. J., & Dalbeth, N. (2017). "What say ye gout experts?" a content analysis of questions about gout posted on the social news website Reddit. BMC musculoskeletal disorders, 18 (1)10.1186/s12891-017-1856-y
Other University of Auckland co-authors: Anna Serlachius, Keith Petrie
- Dalbeth, N., Nicolaou, S., Baumgartner, S., Hu, J., Fung, M., & Choi, H. K. (2017). Presence of monosodium urate crystal deposition by dual-energy CT in patients with gout treated with allopurinol. Annals of the rheumatic diseases10.1136/annrheumdis-2017-212046
- Robinson, P. C., & Dalbeth, N. (2017). Lesinurad for the treatment of hyperuricaemia in people with gout. Expert opinion on pharmacotherapy10.1080/14656566.2017.1401609
- Frecklington, M., Dalbeth, N., McNair, P., Gow, P., Williams, A., Carroll, M., & Rome, K. (2017). Footwear interventions for foot pain, function, impairment and disability for people with foot and ankle arthritis: A literature review. Seminars in arthritis and rheumatism10.1016/j.semarthrit.2017.10.017
- McQueen, F. M., Chapman, P., Pollock, T., D'Souza D, Lee, A. C., Dalbeth, N., ... Doyle, A. (2017). Changes in clinical disease activity are weakly linked to changes in MRI inflammation on treat-to-target escalation of therapy in rheumatoid arthritis. Arthritis research & therapy, 19 (1)10.1186/s13075-017-1433-7
Other University of Auckland co-authors: Arier Lee, Anthony Doyle
- Stewart, S., Pearson, J., Rome, K., Dalbeth, N., & Vandal, A. C. (2017). Analysis of data collected from right and left limbs: Accounting for dependence and improving statistical efficiency in musculoskeletal research. Gait & posture, 59, 182-187. 10.1016/j.gaitpost.2017.10.018
- Dalbeth, N., Pool, B., Chhana, A., Lin, J.-M., Tay, M. L., Tan, P., ... Drake, J. (2017). Lack of Evidence that Soluble Urate Directly Influences Bone Remodelling: A Laboratory and Clinical Study. Calcified tissue international10.1007/s00223-017-0328-6
Other University of Auckland co-authors: Ashika Chhana, Dorit Naot, Anne Horne, Ian Reid, Andrew Grey, Jillian Cornish, Bregina Pool, Mei Lin Tay, Greg Gamble