Dr Nishi Karunasinghe

PhD Macquarie University, Sydney, Australia

Biography

My main research focus has been on selenium health benefit and genetic studies on prostate cancer (PC). 
Next target of my career is to work with replication PC cohorts from large scale studies to reproduce our findings. A collaboration study with the National Cancer Institute, USA has shown a significant delayed diagnosis of high-risk PC in New Zealand compounded by tobacco smoking and the aldo-keto reductase 1C3 rs12529 genotype.  
I was invited to present two concepts at the Australia and New Zealand Urogenital and Prostate Cancer Trials group (ANZUP) in Australia. One was to replicate our findings on genetic association on quality of life (QoL) effects with ADT in a cohort currently receiving enzalutamide. The other was on developing PSA thresholds based on genetics. Two of my international presentations have been named as among the best of the best. Disparities in PC diagnoses and QoL effects with ADT on Mãori men have been presented to the Mãori Health Committee as well as at a Cancer Health Disparities in Minorities conference in the US. I have published 34 research articles and three book chapters related to my work.

Research | Current

Genetic associations of prostate cancer diagnosis, treatment and prognosis outcomes. Genetic association of selenium health benefits. 

Teaching | Current

 I have supervised 15 Summer Student working on prostate cancer related projects.

Postgraduate supervision

I have supervised two PhD students on aspects related to prostate cancer. Currently supervising a Master's student on a study that verifies the influence of Maori medicinal plants in modulating prostate cancer progression using an in vitro model.

Distinctions/Honours

Australia New Zealand Urogenital and Prostate Cancer Trials Group Annual Scientific Meeting (ASM) 2017, Melbourne Australia and ASM 2016 Brisbane, Australia- Best of the Best poster presentations at both instances. Received  Bayer Travel Fellowship for both. 

Selected publications and creative works (Research Outputs)