Dr Nira Paskaranandavadivel

BE, ME(First Class Honours), PhD

Profile Image
Research Fellow

Biography

Nira obtained his Bachleor of Engineering in Biomedical Engineering, Master of Engineering with First Class Honours in Bioengineering, and PhD in Bioengineering, at the University of Auckland.  His doctoral thesis focused on developing novel methods to record and analyse the electrophysiology of the gastrointestinal system using high-resolution mapping techniques.

In 2014, he joined as a Research Fellow at the Auckland Bioengineering Institute in the Gastrointestinal System Group. His research focuses on understanding the electrophysiology of the gut using high-resolution electrical and pressure measurement techniques. 
 

Research | Current

Nira's research focuses on high-resolution mapping methods to investigate the electrophysiology of the gut, with the overall aim to improve and develop new diagnoistics and therauputics for gut disorders. He is involved in developing signal processing and designing software and hardware platforms for basic science and clinical translation with local and international investigators.

International collaborations:

Local Colloborations:

Research groups:

  • Gastrointestinal System Group, Auckland Bioengineering Institute
  • Colorectal Research Group, Department of Surgery
  • Surgical Engineering Laboratory, Auckland Bioengineering Institute & Deptartment of Surgery

Postgraduate supervision

Current 

  • Saeed Alighaleh (PhD Student)  
    • New Foundations for Pacing the Stomach
  • Shasti Ramachandran (ME Student)
    • Magnetic stimulation of evoked sphincter potentials as a test of anorectal neuropathy
  • Johanna Bollerey (ME Student), University of Stuttgart, Germany
    • Methods for Quantitative Analysis of High-density EMG Signals

Completed

  • Miriam Ruhr (2016) - Short and Long ME Thesis, University of Stuttgart, Germany
    • Quantification of Mechanical and Bio-electrical Activity in the Small Intestine
    • Image Registration of Electrodes during Gastrointestinal High-resolution Mapping
  • Thao Vy Vu (July 2016) - Short ME Thesis, University of Stuttgart, Germany
    • Magnetic stimulation of nerves and measurement of muscle activity with high-density electromyograms

Distinctions/Honours

  • 2016, Vice Chancellor’s Research Excellence Award, University of Auckland
  • 2015, Alvarez Award (Best Investigator Award). International Gastrointestinal Electrophysiological Society. Washington DC, (Co-Author)
  • 2015, Robert Stern Award (Best Young Investigator Award). International Gastrointestinal Electrophysiological Society. Washington DC, (Co-Author)
  • 2014, Robert Stern Award (Best Young Investigator Award). International Gastrointestinal Electrophysiological Society. Chicago (Main Author)
  • 2012, Best Student Communicator Award, Riddet CORE Annual Scientific Meeting
  • 2012, Top 25 research posters, EXPOSURE 2012 - Auckland University Postgraduate Research Exposition.
  • 2011, Third place in Multimedia and Live Performance, EXPOSURE 2011 – Auckland University Postgraduate Research Exposition.
  • 2010, Third place at SPARK $100k Challenge.
  • 2010, Best Biotechnology Idea - Chiasma I-Volve Award. 
  • 2010, Ideas Challenge Winner, SPARK.

Areas of expertise

  • Medical Signal Processing
  • Gastrointestinal Electrophysiology
  • Extracellular Mapping Techniques

Committees/Professional groups/Services

  • 2013 - Current: Australasian Neurogastroenterology and Motility Association (ANGMA) Member
  • 2010 - Current: International Gastrointestinal Electrophysiological Society (iGES) Member
  • 2010 - Current: Institute of Electrical and Electronic Engineering (IEEE) Member

Selected publications and creative works (Research Outputs)

  • Paskaranandavadivel, N., Cheng, L. K., Du, P., Rogers, J. M., & O'Grady G (2017). High-resolution mapping of gastric slow-wave recovery profiles: biophysical model, methodology, and demonstration of applications. American journal of physiology. Gastrointestinal and liver physiology, 313 (3), G265-G276. 10.1152/ajpgi.00127.2017
    Other University of Auckland co-authors: Greg O'Grady, Peng Du
  • O'Grady G, Paskaranandavadivel, N., Du, P., Angeli, T., Erickson, J. C., & Cheng, L. K. (2017). Correct techniques for extracellular recordings of electrical activity in gastrointestinal muscle. Nature reviews. Gastroenterology & hepatology, 14 (6)10.1038/nrgastro.2017.15
    Other University of Auckland co-authors: Greg O'Grady, Peng Du, Tim Angeli
  • Angeli, T. R., Du, P., Paskaranandavadivel, N., Sathar, S., Hall, A., Asirvatham, S. J., ... O'Grady G (2017). High-resolution electrical mapping of porcine gastric slow-wave propagation from the mucosal surface. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 29 (5).10.1111/nmo.13010
    URL: http://hdl.handle.net/2292/33442
    Other University of Auckland co-authors: Tim Angeli, John Windsor, Greg O'Grady, Leo Cheng, Peng Du, Shameer Sathar
  • Wang, T. H., Angeli, T. R., Du, P., Paskaranandavadivel, N., Erickson, J. C., Abell, T., ... Grady, G. O. (2017). RELATIONSHIPS BETWEEN SLOW WAVE FREQUENCY, CONDUCTION VELOCITY AND AMPLITUDE IN THE HUMAN STOMACH. Paper presented at Digestive Disease Week, Chicago, IL. 6 May - 9 May 2017. GASTROENTEROLOGY. (pp. 1).
  • Berry, R., Cheng, L. K., Du, P., Paskaranandavadivel, N., Angeli, T. R., Mayne, T., ... O'Grady G (2017). Patterns of Abnormal Gastric Pacemaking After Sleeve Gastrectomy Defined by Laparoscopic High-Resolution Electrical Mapping. Obesity surgery10.1007/s11695-017-2597-6
    Other University of Auckland co-authors: Tim Angeli, Greg O'Grady, Leo Cheng, Peng Du
  • Wang, T.-H., Du, P., Angeli, T., Paskaranandavadivel, N., Erickson, J., Abell, T., ... O'Grady G (2017). Relationships between gastric slow wave frequency, velocity, and extracellular amplitude studied by a joint experimental-theoretical approach. Neurogastroenterology and Motility10.1111/nmo.13152
    Other University of Auckland co-authors: Tim Angeli, Greg O'Grady, Peng Du
  • Du, P., O'Grady G, Paskaranandavadivel, N., Tang, S. J., Abell, T., & Cheng, L. K. (2017). Reply. Experimental physiology, 102 (1)10.1113/ep086141
    Other University of Auckland co-authors: Greg O'Grady, Peng Du
  • Paskaranandavadivel, N., OGrady, G., & Cheng, L. K. (2017). Time-Delay Mapping of High-Resolution Gastric Slow-Wave Activity. IEEE transactions on bio-medical engineering, 64 (1), 166-172. 10.1109/tbme.2016.2548940
    Other University of Auckland co-authors: Greg O'Grady, Leo Cheng

Identifiers

Contact details

Primary location

UNISERVICES HOUSE - Bldg 439
Level 7, Room 740
70 SYMONDS ST
AUCKLAND 1010
New Zealand

Social links

Web links