Dr Nira Paskaranandavadivel

BE, ME(First Class Honours), PhD

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Research Fellow

Biography

Nira obtained his Bachleor of Engineering in Biomedical Engineering, Master of Engineering with First Class Honours in Bioengineering, and PhD in Bioengineering, at the University of Auckland.  His doctoral thesis focused on developing novel methods to record and analyse the electrophysiology of the gastrointestinal system using high-resolution mapping techniques.

In 2014, he joined as a Research Fellow at the Auckland Bioengineering Institute in the Gastrointestinal System Group. His research focuses on understanding the electrophysiology of the gut using high-resolution electrical and pressure measurement techniques. 
 

Research | Current

Nira's research focuses on high-resolution mapping methods to investigate the electrophysiology of the gut, with the overall aim to improve and develop new diagnoistics and therauputics for gut disorders. He is involved in developing signal processing and designing software and hardware platforms for basic science and clinical translation with local and international investigators.

International collaborations:

Local Colloborations:

Research groups:

  • Gastrointestinal System Group, Auckland Bioengineering Institute
  • Colorectal Research Group, Department of Surgery
  • Surgical Engineering Laboratory, Auckland Bioengineering Institute & Deptartment of Surgery

Postgraduate supervision

Current 

  • Saeed Alighaleh (PhD Student)  
    • New Foundations for Pacing the Stomach
  • Jaime Lara Aguayo (PhD Student)
    • ​Novel methods for recording and analysing high-density EMG signals
  • Baozeng Han (PhD Student) 
    • New generation of high-resolution mapping techniques for slow wave refractory analysis
  • Sachira Kuruppu (PhD Student) 
    • Investigation of the relationship between gastrointestinal slow wave, spikes and motility
  • Abishek Kamat (ME Student)
    • Determining the effects of electrode diameter & protrusion on signal morphology of gastric bioelectrical recordings
  • Johanna Bollerey (ME Student), University of Stuttgart, Germany
    • Methods for Quantitative Analysis of High-density EMG Signals

Completed

  • Ashley Abraham (July 2018) - ME Student, UoA
    • High-resolution slow wave mapping of the in-vivo rabbit small intestine
  • Saeed Mollaee (July 2018) - ME Student, UoA
    • Automated techniques for classification and quantification of colonic manometry
  • Shasti Ramachandran (Feb 2018) - ME Student, UoA
    • Magnetic stimulation of evoked sphincter potentials as a test of anorectal neuropathy
  • Miriam Ruhr (2016) - Short and Long ME Thesis, University of Stuttgart, Germany
    • Quantification of Mechanical and Bio-electrical Activity in the Small Intestine
    • Image Registration of Electrodes during Gastrointestinal High-resolution Mapping
  • Thao Vy Vu (July 2016) - Short ME Thesis, University of Stuttgart, Germany
    • Magnetic stimulation of nerves and measurement of muscle activity with high-density electromyograms

Distinctions/Honours

  • 2016, Vice Chancellor’s Research Excellence Award, University of Auckland
  • 2015, Alvarez Award (Best Investigator Award). International Gastrointestinal Electrophysiological Society. Washington DC, (Co-Author)
  • 2015, Robert Stern Award (Best Young Investigator Award). International Gastrointestinal Electrophysiological Society. Washington DC, (Co-Author)
  • 2014, Robert Stern Award (Best Young Investigator Award). International Gastrointestinal Electrophysiological Society. Chicago (Main Author)
  • 2012, Best Student Communicator Award, Riddet CORE Annual Scientific Meeting
  • 2012, Top 25 research posters, EXPOSURE 2012 - Auckland University Postgraduate Research Exposition.
  • 2011, Third place in Multimedia and Live Performance, EXPOSURE 2011 – Auckland University Postgraduate Research Exposition.
  • 2010, Third place at SPARK $100k Challenge.
  • 2010, Best Biotechnology Idea - Chiasma I-Volve Award. 
  • 2010, Ideas Challenge Winner, SPARK.

Areas of expertise

  • Medical Signal Processing
  • Gastrointestinal Electrophysiology
  • Extracellular Mapping Techniques

Committees/Professional groups/Services

  • 2013 - Current: Australasian Neurogastroenterology and Motility Association (ANGMA) Member
  • 2010 - Current: International Gastrointestinal Electrophysiological Society (iGES) Member
  • 2010 - Current: Institute of Electrical and Electronic Engineering (IEEE) Member

Selected publications and creative works (Research Outputs)

  • OGrady, G., Angeli, T. R., Paskaranandavadivel, N., Erickson, J. C., Wells, C., Gharibans, A. A., ... Du, P. (2018). Methods for High-Resolution Electrical Mapping in the Gastrointestinal Tract. IEEE Reviews in Biomedical Engineering10.1109/RBME.2018.2867555
    Other University of Auckland co-authors: Timothy Angeli
  • Kamat, A. A., Alighaleh, S., Cheng, L. K., Paskaranandavadivel, N., & Angeli, T. R. (2018). Effects of electrode diameter and material on the signal morphology of gastric bioelectrical recordings. NEUROGASTROENTEROLOGY AND MOTILITY. (pp. 1).
  • Du, P., O'Grady G, Paskaranandavadivel, N., Tang, S.-J., Abell, T., & Cheng, L. (2018). Evaluation of spatiotemporal gastric slow wave dysrhythmias following acute hyperglycemia. NEUROGASTROENTEROLOGY AND MOTILITY. (pp. 1).
  • Paskaranandavadivel, N., Ramachandran, S., Cheng, L., Collinson, R., Bissett, I., & O'Grady G (2018). High-resolution electromyography for evaluating anorectal physiology. NEUROGASTROENTEROLOGY AND MOTILITY. (pp. 2).
  • Wells, C., Paskaranandavadivel, N., Lin, A., Penfold, J., Rowbotham, D., Cheng, L., ... O'Grady G (2018). An ambulatory acquisition system for fibre-optic high resolution colonic manometry. NEUROGASTROENTEROLOGY AND MOTILITY. (pp. 1).
  • Paskaranandavadivel, N., Sathar, S., Lin, A., Bissett, I., Cheng, L., & O'Grady G (2018). Automated analysis and quantification of high-resolution colonic manometry data. NEUROGASTROENTEROLOGY AND MOTILITY. (pp. 2).
  • Alighaleh, S., Cheng, L. K., O'Grady G, Angeli, T., Sathar, S., Bartlett, A., & Paskaranandavadivel, N. (2018). High-resolution entrainment mapping for human gastric pacing: Design and initial results. NEUROGASTROENTEROLOGY AND MOTILITY. (pp. 1).
  • Wang, T. H.-H., Du, P., Angeli, T. R., Paskaranandavadivel, N., Farrugia, G., Abell, T. L., ... Windsor, J. (2018). Impact of ICC density and aging on slow wave velocity in the human stomach. NEUROGASTROENTEROLOGY AND MOTILITY. (pp. 1).

Identifiers

Contact details

Primary office location

UNISERVICES HOUSE - Bldg 439
Level 7, Room 740
70 SYMONDS ST
AUCKLAND 1010
New Zealand

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