Dr Nira Paskaranandavadivel

BE, ME(First Class Honours), PhD

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Senior Research Fellow

Biography

Nira obtained his Bachleor of Engineering in Biomedical Engineering, Master of Engineering with First Class Honours in Bioengineering, and PhD in Bioengineering, at the University of Auckland.  His doctoral thesis focused on developing novel methods to record and analyse the electrophysiology of the gastrointestinal system using high-resolution mapping techniques.

In 2014, he joined as a Research Fellow at the Auckland Bioengineering Institute in the Gastrointestinal System Group. 

Research | Current

Nira's research focuses on high-resolution mapping methods to investigate the electrophysiology of the gut, with the overall aim to improve and develop new diagnoistics and therauputics for gut disorders. He is involved in developing signal processing and designing software and hardware platforms for basic science and clinical translation with local and international investigators.

International collaborations:

Local Colloborations:

Research groups:

Postgraduate supervision

Current 

  • Nipuni Nagahawatte (ME Student)
    • Micro-electrode arrays recordings for recording slow wave activity
  • Kiara Miller (ME Student)
    • Slow Wave Mapping of the Rabbit Small Intestine, Caecum and Colon
  • Saeed Alighaleh (PhD Student)  
    • New Foundations for Pacing the Stomach
  • Jaime Lara Aguayo (PhD Student)
    • ​Novel methods for recording and analysing high-density EMG signals
  • Baozeng Han (PhD Student) 
    • New generation of high-resolution mapping techniques for slow wave refractory analysis
  • Sachira Kuruppu (PhD Student) 
    • Investigation of the relationship between gastrointestinal slow wave, spikes and motility
  • Nima Hosseini (PhD Student)
    • Physiolocally Based Model of Gastric Motility and Emptying

Completed

  • Ashley Abraham (July 2018) - ME Student, UoA 
    • Fowlds Memorial Prize (ABI), for Best ME thesis
    • High-resolution slow wave mapping of the in-vivo rabbit small intestine
  • Abishek Kamat (ME Student)
    • Determining the effects of electrode diameter & protrusion on signal morphology of gastric bioelectrical recordings
  • Saeed Mollaee (July 2018) - ME Student, UoA
    • Automated techniques for classification and quantification of colonic manometry
  • Johanna Bollerey (2018) - ME Student, University of Stuttgart, Germany
    • Methods for Quantitative Analysis of High-density EMG Signals
  • Shasti Ramachandran (Feb 2018) - ME Student, UoA
    • Magnetic stimulation of evoked sphincter potentials as a test of anorectal neuropathy
  • Miriam Ruhr (2016) - Short and Long ME Thesis, University of Stuttgart, Germany
    • Quantification of Mechanical and Bio-electrical Activity in the Small Intestine
    • Image Registration of Electrodes during Gastrointestinal High-resolution Mapping
  • Thao Vy Vu (July 2016) - Short ME Thesis, University of Stuttgart, Germany
    • Magnetic stimulation of nerves and measurement of muscle activity with high-density electromyograms

Distinctions/Honours

  • 2018, Robert Stern Award (Best Young Investigator Award). International Gastrointestinal Electrophysiological Society. Washington DC, (Co-Author)
  • 2016, Vice Chancellor’s Research Excellence Award, University of Auckland
  • 2015, Alvarez Award (Best Investigator Award). International Gastrointestinal Electrophysiological Society. Washington DC, (Co-Author)
  • 2015, Robert Stern Award (Best Young Investigator Award). International Gastrointestinal Electrophysiological Society. Washington DC, (Co-Author)
  • 2014, Robert Stern Award (Best Young Investigator Award). International Gastrointestinal Electrophysiological Society. Chicago (Main Author)
  • 2012, Best Student Communicator Award, Riddet CORE Annual Scientific Meeting
  • 2012, Top 25 research posters, EXPOSURE 2012 - Auckland University Postgraduate Research Exposition.
  • 2011, Third place in Multimedia and Live Performance, EXPOSURE 2011 – Auckland University Postgraduate Research Exposition.
  • 2010, Third place at SPARK $100k Challenge.
  • 2010, Best Biotechnology Idea - Chiasma I-Volve Award. 
  • 2010, Ideas Challenge Winner, SPARK.

Areas of expertise

  • Medical Signal Processing
  • Gastrointestinal Electrophysiology
  • Extracellular Mapping Techniques

Committees/Professional groups/Services

  • 2013 - Current: Australasian Neurogastroenterology and Motility Association (ANGMA) Member
  • 2010 - Current: International Gastrointestinal Electrophysiological Society (iGES) Member
  • 2010 - Current: Institute of Electrical and Electronic Engineering (IEEE) Member

Selected publications and creative works (Research Outputs)

  • Jaung, R., Varghese, C., Lin, A. Y., Paskaranandavadivel, N., Du, P., Rowbotham, D., ... Bissett, I. (2020). High-Resolution Colonic Manometry Pressure Profiles Are Similar in Asymptomatic Diverticulosis and Controls (vol 41, pg 861, 2020). DIGESTIVE DISEASES AND SCIENCES10.1007/s10620-020-06524-8
    Other University of Auckland co-authors: Greg O'Grady, Rebekah Jaung, Ian Bissett
  • Paskaranandavadivel, N., Varghese, C., Lara, J., Ramachandran, S., Cheng, L., Holobar, A., ... Stinear, C. (2020). A Novel High-Density Electromyography Probe for Evaluating Anorectal Neurophysiology: Design, Human Feasibility Study, and Validation with Trans-Sacral Magnetic Stimulation. ANNALS OF BIOMEDICAL ENGINEERING10.1007/s10439-020-02581-2
    Other University of Auckland co-authors: Cathy Stinear, Armen Gharibans, Ian Bissett, Greg O'Grady
  • Sayat, M., Aghababaie, Z., Cheng, L. K., Paskaranandavadivel, N., Avci, R., Rickus, J., ... Angeli, T. R. (2020). Transmural Temperature Monitoring to Quantify Thermal Conduction and Lesion Formation during Gastric Ablation, an Emerging Therapy for Gastric Dysrhythmias. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 10.1109/EMBC44109.2020.9176026
    Other University of Auckland co-authors: Tim Angeli
  • Han, H., Cheng, L. K., Avci, R., & Paskaranandavadivel, N. (2020). Detection of Slow Wave Propagation Direction Using Bipolar High-Resolution Recordings. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 10.1109/EMBC44109.2020.9175303
  • Avci, R., Paskaranandavadivel, N., Eichler, C. E., Lam, B. Y. C., Angeli, T. R., Bradshaw, L. A., & Cheng, L. K. (2020). Computational Reconstruction of 3D Stomach Geometry using Magnetic Field Source Localization. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 10.1109/EMBC44109.2020.9176431
    Other University of Auckland co-authors: Tim Angeli
  • Athavale, O. N., Paskaranandavadivel, N., Angeli, T. R., Avci, R., & Cheng, L. K. (2020). Design of Pressure Sensor Arrays to Assess Electrode Contact Pressure during in Vivo Recordings in the Gut. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 10.1109/EMBC44109.2020.9175843
    Other University of Auckland co-authors: Tim Angeli
  • Kuruppu, S., Cheng, L. K., Angeli, T. R., Avci, R., & Paskaranandavadivel, N. (2020). High-Resolution Mapping of Intestinal Spike Bursts and Motility. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 10.1109/EMBC44109.2020.9175879
    Other University of Auckland co-authors: Tim Angeli
  • Miller, K. J. W., Cheng, L. K., Angeli, T. R., Avci, R., & Paskaranandavadivel, N. (2020). Design and Application of an Inflatable Cuff to Aid High-Resolution Intestinal Slow Wave Recordings. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 10.1109/EMBC44109.2020.9175219
    Other University of Auckland co-authors: Tim Angeli

Identifiers

Contact details

Primary office location

UNISERVICES HOUSE - Bldg 439
Level 7, Room 740
70 SYMONDS ST
AUCKLAND 1010
New Zealand

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