Professor Poul Michael Fonss Nielsen
BSc BE PhD
Poul has a Bachelor of Science in Maths and Physics, and a Bachelor of Engineering and Phd in Engineering Science, from the University of Auckland.
Poul is affiliated with several groups within the University:
Research | Current
Poul's research focuses on using novel instrumentation, detailed computational models, and quantitative descriptions of physical processes to gain a better understanding of human physiology. Many of his projects couple mathematical modelling with innovative instrumentation to improve our ability to understand and interpret measurements of complex biological systems, subject to the constraints of well-understood physical conservation and balance laws.
Poul's research projects include:
- Physiome: an integrated multi-centric program to design, develop, implement, test and document, archive and disseminate quantitative information and integrative models of the functional behaviour of organelles, cells, tissues, organs, and organisms;
- CellML: an open standard to store and exchange computer-based mathematical models;
- FieldML: a declarative language for representing the dynamic geometry and solution fields of computational models;
- Breast mechanics: computational biomechanical models to improve the detection of breast cancer using information obtained from a variety of imaging modalities;
- Muscle microcalorimetry: to identify the dynamic stiffness of isolated rat trabeculae while simultaneously recording muscle heat production;
- Soft tissue mechanics: coupling large deformation theory, structurally-based constitutive relations, and nonlinear identification techniques to understand the mechanics of soft tissues;
- Pelvic floor mechanics: modelling the second stage of labour and pelvic floor prolapse;
- Modelling shaken baby syndrome: gaining an understanding of the relationships between shaking insults and soft tissue injury in infants;
- Bioinstrumentation and medical devices: development of novel instrumentation for measuring biophysical properties of living tissue (microrobotics, stereoscopy, optical coherence tomography, spectral imaging, interferometry).
- Thiranja Prasad Babarenda Gamage, Modelling and identifying the mechanical properties of skin and underlying tissues
- Amir Haji Rassouliha, Hardware acceleration of cross-correlation-based identification of surface geometry of deformable bodies
- Matthew Parker, Model-based identification of the mechanical properties of living skin
- Nikini Puhulwelle Gamage, Model-based prediction of brain injury associated with shaken baby syndrome
- Adam Reeve,The mechanics of vascularised tissue
- Samuel Richardson, Development of an optical coherence tomography based skin cancer diagnostic tool
- Oliver Thompson, Interpretation and Medical Application of Laser Biospeckle
- 2011 - 2013: James Cook Research Fellowship, Royal Society of New Zealand.
- 2011 - present: Liggins Institute Honorary Professor.
- 2010: OCCAM Visiting Fellow, University of Oxford.
Selected publications and creative works (Research Outputs)
- Johnston, C. M., Nielsen, P. M. F., Taberner, A. J., & Hunter, I. W. (2017). Vapor pressure thermometry at room temperature. I2MTC 2017 - 2017 IEEE International Instrumentation and Measurement Technology Conference, Proceedings. 10.1109/I2MTC.2017.7969857
Other University of Auckland co-authors: Andrew Taberner
- Kruger, J. A., Budgett, S. C., Wong, V., Nielsen, P. M. F., Nash, M. P., Smalldridge, J., ... Taberner, A. J. (2017). Characterizing levator-ani muscle stiffness pre- and post-childbirth in European and Polynesian women in New Zealand: a pilot study. Acta obstetricia et gynecologica Scandinavica10.1111/aogs.13186
Other University of Auckland co-authors: Jennifer Kruger, Stephanie Budgett, Martyn Nash, Jackie Smalldridge, Andrew Taberner
- Babarenda Gamage, T. P., Nielsen, P. M. F., & Nash, M. P. (2017). Clinical applications of breast biomechanics. In Y. Payan, J. Ohayon (Eds.) Biomechanics of Living Organs: Hyperelastic Constitutive Laws for Finite Element Modeling (pp. 215-242). Elsevier. Related URL.
Other University of Auckland co-authors: Thiranja Babarenda Gamage, Martyn Nash
- HajiRassouliha, A., Taberner, A. J., Nash, M. P., & Nielsen, P. M. F. (2017). Motion correction using subpixel image registration. Lecture Notes in Computer Science: Reconstruction, Segmentation, and Analysis of Medical Images, 10129, 14-23. Athens, Greece: Springer. 10.1007/978-3-319-52280-7_2
Other University of Auckland co-authors: Amir Haji Rassouliha, Andrew Taberner, Martyn Nash
- Cheuk, M., Anderson, A., Han, J.-C., Lippok, N., Vanholsbeeck, F., Ruddy, B., ... Taberner, A. J. (2017). 4D imaging of cardiac trabeculae contracting in vitro using gated OCT. IEEE Transactions on Biomedical Engineering, 64 (1), 218-224. 10.1109/TBME.2016.2553154
Other University of Auckland co-authors: Andrew Taberner, June-Chiew Han, Frederique Vanholsbeeck, Bryan Ruddy, Denis Loiselle
- Cooling, M. T., Nickerson, D., Nielsen, P., & Hunter, P. (2016). Modular Modelling with Physiome Standards. The Journal of Physiology, 594 (23), 6817-6831. 10.1113/JP272633
Other University of Auckland co-authors: Peter Hunter, David Nickerson
- Parker, M. D., Jones, L. A., Hunter, I. W., Taberner, A. J., Nash, M. P., & Nielsen, P. M. F. (2016). Multidirectional In Vivo Characterization of Skin Using Wiener Nonlinear Stochastic System Identification Techniques. Journal of Biomechanical Engineering, 139 (1)10.1115/1.4034993
Other University of Auckland co-authors: Andrew Taberner, Martyn Nash
- Yan, X., Kruger, J. A., Li, X., Nielsen, P. M. F., & Nash, M. P. (2016). Modeling the second stage of labor. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 8 (6), 506-516. 10.1002/wsbm.1351
Other University of Auckland co-authors: Jennifer Kruger, Martyn Nash