Associate Professor Rachael Parke
RN, MHSc (hons), PhD
I am an Associate Professor at the University of Auckland in the School of Nursing as well as the Nurse Senior Research Fellow in the Cardiothoracic and Vascular ICU at Auckland City Hospital. I have been involved in clinical research since 2004 and have been responsible for the CVICU becoming one of the busiest and most recognised intensive care research units in Australasia. I have extensive involvement in many local and international investigator initiated clinical trials as an investigator and member of the trial steering committee and have an impressive publication and funding record.
In addition to my work in CVICU, Rachael has been the Secretary of the Australian and New Zealand Intensive Care Society Clinical Trials Group (ANZICS-CTG), one of the world’s leading trials groups in critical care. She is the only non-physician to have held an elected office-bearer position within the ANZICS-CTG.
I also hold ahonorary positions with Monash University (Melbourne) and the Medical Research Institute of New Zealand (Wellington). I am currently the chief investigator on a recently completed 700 patient multi-centre, randomised controlled trial of conservative fluid administration versus standard fluid administration in patients after cardiac surgery.
I was awarded my PhD from the University of Auckland in 2014. My thesis “High Flow Nasal Oxygen Therapy in Patients after Cardiac Surgery” was awarded the Vice-Chancellors Award - Best Doctoral Thesis 2014.
I have published over 85 articles and been named on peer reviewed research grants exceeding NZ$9.6 million. My research interests include enhanced recovery after thoracic surgery, oxygen therapy, non-invasive ventilation, fluid management after cardiac surgery and cardiac surgery associated acute kidney injury.
One of my other passions is establishing the next generation of researchers and to do this I have been instrumental in developing two research courses: BASIC Clinical Research and BASIC Research Coordination which have been run successfully in 6 countries to date.
I have also established a podcast series aimed at nurses, academics and allied health professionals working in the intensive care environment or interested in establishing their own academic careers. Listen to these at Critical 2 Your Success.
Research | Current
Principal Investigator - Fluids After Bypass Study. A Multi-centre, Open Label, Randomised Controlled Trial to Compare a Conservative Fluid Management Strategy to Usual Care in Participants after Cardiac Surgery. This study was undertaken in all 5 publically funded cardiac ICUs in New Zealand enrolling 700 patients.
Principal Investigator - An observational study of critically ill patients with severe acute respiratory distress syndrome in Australia and New Zealand to determine mortality: SAGE ANZ. We plan to prospectively assess the management of moderate-severe ARDS patients in intensive care units in Australia and New Zealand.
Principal Investigator New Zealand - Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest. The TAME trial is a phase III, multi-centre, randomised, parallel-group, clinical trial in resuscitated cardiac arrest patients admitted to the intensive care unit to determine whether targeted therapeutic mild hypercapnia (TTMH) improves neurological outcome at 6 months compared to standard care (targeted normocapnia) (TN). I am the successful recipient of a Health Research Council of New Zealand project grant of $1.19 million for this study.
Teaching | Current
Course Coordinator NURSING 782 - Research Methods in Nursing and Health
Nicole Jenkins Pet therapy in the ICU an integrative literature review. 2018
Rachael McConnachie Delayed defecation and impact on brain injury. 2019
Maxine Anderson Impact of cardiac surgery on patients aged over 80 years. 2019
Sheila Baccus Fasting before an elective coronary angiogram and angioplasty. 2019
2016 Senior Fellowship, Green Lane Research and Educational Fund Board
2016 Star Research Achievement Award, Society of Critical Care Medicine 45th Critical Care Congress, February 2016, Orlando, Florida, USA for the abstract titled “Preoperative Risk Influences Outcomes when a Restrictive Fluid Regime is used after Cardiac Surgery”
2015 Abstract Scholarship, Assembly of Nursing, American Thoracic Society Conference, Denver, USA
2015 Vice-Chancellor's Award for Best Doctoral Thesis 2014, The University of Auckland
2014 The Green Lane Trophy - Best Scientific Presentation
2011 Clinical Research Training Fellowship, Health Research Council of New Zealand
2010 PhD scholarship, Green Lane Research and Educational Fund Board
2010 Best presentation - Australia New Zealand Intensive Care Society Clinical Trial Group Research Development Day
2009 Best Nursing Poster – Auckland District Health Board Research Week
2008 Best Nursing Poster – Auckland District Health Board Research Week
2007 Best Nursing Poster – Auckland District Health Board Research Week
2007 Rebecca Roberts Scholarship, The University of Auckland
1996 Fred Furkitt Prize for special contribution to nursing, Green Lane Hospital
Co-lead BASIC Clinical Research Course
Lead BASIC Research Coordination Course
Selected publications and creative works (Research Outputs)
- McGuinness, S. P., Parke, R. L., Drummond, K., Willcox, T., & Bailey, M. (2016). A Multicenter, Randomized, Controlled Phase IIb Trial of Avoidance of Hyperoxemia during Cardiopulmonary Bypass. Anesthesiology, 125 (3), 465-473. 10.1097/ALN.0000000000001226
- Eastwood, G. M., Schneider, A. G., Suzuki, S., Peck, L., Young, H., Tanaka, A., ... Parke, R. L. (2016). Targeted therapeutic mild hypercapnia after cardiac arrest: A phase II multi-centre randomised controlled trial (the CCC trial). Resuscitation, 104, 83-90. 10.1016/j.resuscitation.2016.03.023
- Parke, R. L. (2016). A randomized feasibility study to assess a novel strategy to rationalize fluid in patients after cardiac surgery. British Journal of Anaesthesia, 117 (1), 141-141. 10.1093/bja/aew162
- Fanning, N., Galvin, S., Parke, R., Gilroy, J., Bellomo, R., & McGuinness, S. (2016). A Prospective Study of the Timing and Accuracy of Neutrophil Gelatinase-Associated Lipocalin Levels in Predicting Acute Kidney Injury in High-Risk Cardiac Surgery Patients. Journal of cardiothoracic and vascular anesthesia, 30 (1), 76-81. 10.1053/j.jvca.2015.07.034