Dr Ralph James Stevenson

Biography

Ralph is an Honorary Senior Lecturer with the School of Chemical Sciences, Faculty of Science.

Research interests

  • Medicinal chemistry
  • Synthetic organic chemistry
  • Cancer research
  • Anticancer drug design
  • Anticancer drug development
  • Tumour hypoxia
  • CRAC channel inhibitors
  • Flavour chemistry of foods

Teaching | Current

FOODSCI 301

FOODSCI 708

Selected publications and creative works (Research Outputs)

  • Azimi, I., Flanagan, J. U., Stevenson, R. J., Inserra, M., Vetter, I., Monteith, G. R., & Denny, W. A. (2017). Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a Fluorescence Imaging Plate Reader assay. Bioorganic & medicinal chemistry, 25 (1), 440-449. 10.1016/j.bmc.2016.11.007
    Other University of Auckland co-authors: Jack Flanagan, Bill Denny
  • Chang, J. Y.-C., Lu, G.-L., Stevenson, R. J., Brothers, P. J., Clark, G. R., Botting, K. J., ... Denny, W. A. (2013). Cross-bridged cyclen or cyclam Co(III) complexes containing cytotoxic ligands as hypoxia-activated prodrugs. Inorg Chem, 52 (13), 7688-7698. 10.1021/ic4006967
    URL: http://hdl.handle.net/2292/24217
    Other University of Auckland co-authors: David Ware, Bill Denny, Penelope Brothers, William Wilson, Moana Tercel, Leon Lu, George Clark
  • Tercel, M., Marnane, R. N., Tatnell, M. A., Stevenson, R. J., Halim, A., Lu, G.-L., ... Wilson, W. R. (2013). An indoline-derived compound that markedly reduces mouse body weight. Int J Obes (Lond), 37 (5), 685-692. 10.1038/ijo.2012.97
    Other University of Auckland co-authors: Bill Denny, William Wilson, Kathy Mountjoy, Moana Tercel, Rebecca Marnane
  • Tercel, M., Marnane, R. N., Tatnell, M. A., Stevenson, R. J., Halim, A., Lu, G. L., ... Wilson, W. R. (2013). An indoline-derived compound that markedly reduces mouse body weight. International Journal of Obesity, 37 (5), 685-692. 10.1038/ijo.2012.97
    Other University of Auckland co-authors: Bill Denny, William Wilson, Kathy Mountjoy, Leon Lu, Rebecca Marnane
  • Garcia, C. V., Stevenson, R. J., Atkinson, R. G., Winz, R. A., & Quek, S. Y. (2013). Changes in the bound aroma profiles of 'Hayward' and 'Hort16A' kiwifruit (Actinidia spp.) during ripening and GC-olfactometry analysis. Food Chemistry, 137 (1-4), 45-54. 10.1016/j.foodchem.2012.10.002
    Other University of Auckland co-authors: Siew-Young Quek
  • Garcia, C. V., Stevenson, R. J., Quek, S.-Y., Garcia, C. V., Atkinson, R. G., Winz, R. A., & Stevenson, R. J. (2013). Changes in the bound aroma profiles of 'Hayward' and 'Hort16A' kiwifruit (Actinidia spp.) during ripening and GC-olfactometry analysis. Food Chemistry, 137 (1), 45-54. 10.1016/j.foodchem.2012.10.002
    Other University of Auckland co-authors: Siew-Young Quek
  • Garcia, C. V., Quek, S. Y., Stevenson, R. J., & Winz, R. A. (2012). Characterisation of bound volatile compounds of a low flavour kiwifruit species: Actinidia eriantha. Food Chemistry, 134 (2), 655-661. 10.1016/j.foodchem.2012.02.148
    Other University of Auckland co-authors: Siew-Young Quek
  • Stevenson, R. J., Denny, W. A., Tercel, M., Pruijn, F. B., & Ashoorzadeh, A. (2012). Nitro seco analogues of the duocarmycins containing sulfonate leaving groups as hypoxia-activated prodrugs for cancer therapy. J Med Chem, 55 (6), 2780-2802. 10.1021/jm201717y
    Other University of Auckland co-authors: Frederik Pruijn, Moana Tercel, Bill Denny, Amir Ashoorzadeh

Contact details

Primary location

M&HS BUILDING 504 - Bldg 504
Level 1, Room 120
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand