Dr Richard Lawrence Kingston

PhD (Massey)

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Senior Lecturer

Biography

Richard Kingston is a Senior Lecturer in Structural Biology and has been on the Auckland Faculty since 2005. He obtained his PhD in Biochemistry from Massey University, and was a postdoctoral fellow at Purdue University, and the University of Oregon, before returning to New Zealand.

Research | Current

Our research is focused on understanding viral replication machinery, and the fundamental physical properties of proteins. We make use of an array of biophysical and structural techniques as part of this work, including X-ray diffraction, electron microscopy, spectroscopy and calorimetry.  Major areas of investigation are

  • The Replication Machinery of RNA viruses
  • The Effects of Chemical Chaperones on Protein Conformational Stability.
  • Conformational Dynamics and its Links to Protein Function.
  • The Modeling of Complex Biological Binding Processes.
  • Direct Phasing Methods in Protein Crystallography

 

Teaching | Current

BIOSCI 349 Biomedical Microbiology (Course Coordinator and Director)

BIOSCI 350 Protein Structure and Function 

BIOSCI 737 High Resolution Imaging of Biological Molecules (Course Coordinator and Director)

BIOSCI 746 The Molecular Machinery of the Cell (Course Coordinator and Director)

Distinctions/Honours

  • NZ HRC Hercus Fellowship

Areas of expertise

Structural Biology, Biophysical Chemistry

Selected publications and creative works (Research Outputs)

As of 29 October 2020 there will be no automatic updating of 'selected publications and creative works' from Research Outputs. Please continue to keep your Research Outputs profile up to date.
  • Douglas, J., Kingston, R., & Drummond, A. J. (2020). Bayesian inference and comparison of stochastic transcription elongation models. PLoS computational biology, 16 (2)10.1371/journal.pcbi.1006717
    Other University of Auckland co-authors: Alexei Drummond
  • Herr, N., Webby, M. N., Bulloch, E. M. M., Schmitz, M., & Kingston, R. L. (2019). NMR chemical shift assignment of the C-terminal region of the Menangle virus phosphoprotein. Biomolecular NMR assignments, 13 (1), 195-199. 10.1007/s12104-019-09876-z
    Other University of Auckland co-authors: Esther Bulloch, Michael Schmitz, Nicole Herr
  • Webby, M. N., Sullivan, M. P., Yegambaram, K. M., Radjainia, M., Keown, J. R., & Kingston, R. L. (2019). A method for analyzing the composition of viral nucleoprotein complexes, produced by heterologous expression in bacteria. Virology, 527, 159-168. 10.1016/j.virol.2018.11.013
    Other University of Auckland co-authors: Matthew Sullivan
  • Doktorova, M., Heberle, F. A., Kingston, R. L., Khelashvili, G., Cuendet, M. A., Wen, Y., ... Dick, R. A. (2017). Cholesterol promotes protein binding by affecting membrane electrostatics and solvation properties. Biophysical Journal, 113 (9), 2004-2015. 10.1016/j.bpj.2017.08.055
  • Hausrath, A. C., & Kingston, R. L. (2017). Conditionally disordered proteins: Bringing the environment back into the fold. Cellular and Molecular Life Sciences, 74 (17), 3149-3162. 10.1007/s00018-017-2558-1
  • Jaballah, S. A., Bailey, G. D., Desfosses, A., Hyun, J., Mitra, A. K., & Kingston, R. L. (2017). In vitro assembly of the Rous Sarcoma Virus capsid protein into hexamer tubes at physiological temperature. Scientific Reports, 7 (1)10.1038/s41598-017-02060-0
    Other University of Auckland co-authors: Alok Mitra
  • Sullivan, M. P., Groessl, M., Meier, S. M., Kingston, R. L., Goldstone, D. C., & Hartinger, C. G. (2017). The metalation of hen egg white lysozyme impacts protein stability as shown by ion mobility mass spectrometry, differential scanning calorimetry, and X-ray crystallography. Chemical Communications, 53 (30), 4246-4249. 10.1039/c6cc10150j
    URL: http://hdl.handle.net/2292/42770
    Other University of Auckland co-authors: Christian Hartinger, David Goldstone, Matthew Sullivan
  • Jeon, J., Qiao, X., Hung, I., Mitra, A. K., Desfosses, A., Huang, D., ... Gan, Z. (2017). Structural model of the tubular assembly of the rous sarcoma virus capsid protein. Journal of the American Chemical Society, 139 (5), 2006-2013. 10.1021/jacs.6b11939
    Other University of Auckland co-authors: Alok Mitra

Identifiers

Contact details

Primary office location

THOMAS BUILDING EXTENSION - Bldg 110N
Level 4, Room 4006
3A SYMONDS ST
AUCKLAND CENTRAL
AUCKLAND 1010
New Zealand

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