Dr Swarna Akuratiya Gamage

Senior Research Fellow

In: Auckland Cancer Society Research Centre » Medical Science » Faculty of Medical and Health Sciences

Selected publications and creative works (Research Outputs)

Gamage, S. A., Giddens, A. C., Tsang, K. Y., Flanagan, J. U., Kendall, J. D., Lee, W.-J., ... Shepherd, P. R. (2017). Synthesis and biological evaluation of sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474. Bioorganic and Medicinal Chemistry, 25 (20), 5859-5874. 10.1016/j.bmc.2017.09.025
URL: http://hdl.handle.net/2292/41240
Other University of Auckland co-authors: Gordon Rewcastle, Anna Giddens, Bill Denny, Jack Flanagan, Christina Buchanan, Stephen Jamieson, Woo Lee
Rewcastle, G. W., Kolekar, S., Buchanan, C. M., Gamage, S. A., Giddens, A. C., Tsang, K. Y., ... Smith, G. C. (2017). Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors. Oncotarget, 8 (29), 47725-47740. 10.18632/oncotarget.17730
URL: http://hdl.handle.net/2292/34774
Other University of Auckland co-authors: Peter Shepherd, Gordon Rewcastle, Christina Buchanan, Bill Denny, Stephen Jamieson, Anna Giddens, Woo Lee
Harvey, M., Sleigh, J., Voss, L., Jose, J., Gamage, S., Pruijn, F., ... Denny, W. (2015). Development of rapidly metabolized and ultra-short-acting ketamine analogs. Anesthesia and Analgesia, 121 (4), 925-933. 10.1213/ane.0000000000000719
URL: http://hdl.handle.net/2292/26105
Other University of Auckland co-authors: Jiney Jose, Frederik Pruijn, Bill Denny, Jamie Sleigh
Evans, G. L., Gamage, S. A., Bulloch, E. M. M., Baker, E. N., Denny, W. A., & Lott, J. S. (2015). Corrigendum: Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis. Chembiochem : a European journal of chemical biology, 16 (5)10.1002/cbic.201500098
Other University of Auckland co-authors: Esther Bulloch, Bill Denny, Shaun Lott
Jose, J., Gamage, S. A., Harvey, M. G., Voss, L. J., Sleigh, J. W., & Denny, W. A. (2013). Structure-activity relationships for ketamine esters as short-acting anaesthetics. Bioorg Med Chem, 21 (17), 5098-5106. 10.1016/j.bmc.2013.06.047
URL: http://hdl.handle.net/2292/32034
Other University of Auckland co-authors: Jiney Jose, Bill Denny, Jamie Sleigh
Gamage, S. A., Brooke, D. G., Redkar, S., Datta, J., Jacob, S. T., & Denny, W. A. (2013). Structure-activity relationships for 4-anilinoquinoline derivatives as inhibitors of the DNA methyltransferase enzyme DNMT1. Bioorg Med Chem, 21 (11), 3147-3153. 10.1016/j.bmc.2013.03.033
Other University of Auckland co-authors: Bill Denny
Rewcastle, G. W., Gamage, S. A., Flanagan, J. U., Kendall, J. D., Denny, W. A., Baguley, B. C., ... Kolekar, S. (2013). Synthesis and biological evaluation of novel phosphatidylinositol 3-kinase inhibitors: Solubilized 4-substituted benzimidazole analogs of 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole (ZSTK474). Eur J Med Chem, 64, 137-147. 10.1016/j.ejmech.2013.03.038
URL: http://hdl.handle.net/2292/34223
Other University of Auckland co-authors: Jack Flanagan, Peter Shepherd, Bill Denny, Gordon Rewcastle, Christina Buchanan, Stephen Jamieson, Sharada Kolekar, Woo Lee
Rewcastle, G. W., Gamage, S. A., Flanagan, J. U., Frederick, R., Denny, W. A., Baguley, B. C., ... Marshall, E. S. (2011). Synthesis and biological evaluation of novel analogues of the pan class I phosphatidylinositol 3-kinase (PI3K) inhibitor 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole (ZSTK474). J Med Chem, 54 (20), 7105-7126. 10.1021/jm200688y
URL: http://hdl.handle.net/2292/9363
Other University of Auckland co-authors: Jack Flanagan, Peter Shepherd, Bill Denny, Gordon Rewcastle, Christina Buchanan, Stephen Jamieson, Woo Lee