Dr Simon Joseph OCarroll

BSc, MSc (First Class Honours), PhD


Research interests

Research | Current

Simon is a Senior Lecturer in the Department of Anatomy and Medical Imaging and Head of the Spinal Cord Injury Research Group, located in the Centre for Brain Research. Simon's current research interests involve understanding the mechanisms of damage involved in spinal cord injury and developing therapeutic interventions that modulate neuroinflammation and scar formation following injury. He is also interested in the role of the blood brain barrier in central nervous system disease development and uses in vivo and real time cell culture methods to study changes that occur at the blood brain barrier following neuroinflammatory and traumatic insult.

Teaching | Current

MEDSCI 201 - Human Structure and Function - Course Director

MEDSCI 206 - Principles of Neuroscience

MEDSCI 317 - Integrative Neuroscience: From Fetus to Adult

MEDSCI 720 - Biomedical Research Techniques

MEDSCI 727 - Advanced Neuroscience: Neurophysiology

MBCHB 221A - Musculoskeletal System

MBCHB 321A - The Nervous System

MAORIHTH 21H - Biology

Postgraduate supervision

Connor Clemett, PhD - supervisor

Sam McCullough, PhD - supervisor

Zahra Laouby, PhD - joint supervisor

Anusha Dravid, PhD - co-supervisor

Joy Reginald-Opara, PhD - co-supervisor

Ernest Cheah, PhD - co-supervisor

Rebecca Johnson, PhD - co-supervisor

Akshata Anchan, PhD - co-supervisor





Areas of expertise

Spinal cord injury


Blood brain barrier

Real-time cell culture analyis

Selected publications and creative works (Research Outputs)

As of 29 October 2020 there will be no automatic updating of 'selected publications and creative works' from Research Outputs. Please continue to keep your Research Outputs profile up to date.
  • Mao, Y., Tonkin, R., Nguyen, T., O'Carroll S, Nicholson, L., Green, C., ... Gorrie, C. (2017). Systemic administration of Connexin43 mimetic peptide improves functional recovery after traumatic spinal cord injury in adult rats. Journal of Neurotrauma, 34 (3), 707-719. 10.1089/neu.2016.4625
    Other University of Auckland co-authors: Colin Green, Louise Nicholson
  • Griffin, J. M., Kho, D., Graham, E. S., Nicholson, L. F. B., & O'Carroll SJ (2016). Statins inhibit fibrillary β-amyloid induced inflammation in a model of the human blood brain barrier. PLoS One, 11 (6)10.1371/journal.pone.0157483
    Other University of Auckland co-authors: Louise Nicholson, Scott Graham
  • O'Carroll SJ, Kho, D. T., Wiltshire, R., Nelson, V., Rotimi, O., Johnson, R., ... Graham, E. S. (2015). Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells. Journal of Neuroinflammation, 1210.1186/s12974-015-0346-0
    Other University of Auckland co-authors: Scott Graham, Catherine Angel, Lola Mugisho, Rebecca Johnson
  • O'Carroll SJ, Gorrie, C. A., Velamoor, S., Green, C. R., & Nicholson, L. F. B. (2013). Connexin43 mimetic peptide is neuroprotective and improves function following spinal cord injury. Neuroscience Research, 75 (3), 256-267. 10.1016/j.neures.2013.01.004
    Other University of Auckland co-authors: Colin Green, Louise Nicholson
  • O'Carroll SJ, Becker, D. L., Davidson, J. O., Gunn, A. J., Nicholson, L. F. B., & Green, C. R. (2013). The use of connexin-based therapeutic approaches to target inflammatory diseases. Methods in Molecular Biology, 1037, 519-546. 10.1007/978-1-62703-505-7_31
    Other University of Auckland co-authors: Louise Nicholson, Alistair Gunn, Joanne Davidson
  • O'Carroll SJ, Alkadhi, M., Nicholson, L. F. B., & Green, C. R. (2008). Connexin43 mimetic peptides reduce swelling, astrogliosis, and neuronal cell death after spinal cord injury. CELL COMMUNICATION AND ADHESION, 15 (1-2), 27-42. 10.1080/15419060802014164
    Other University of Auckland co-authors: Louise Nicholson, Colin Green

Contact details

Primary office location

M&HS BUILDING 502 - Bldg 502
Level 5, Room 501
New Zealand