Mrs Susan Margaret Pullen

Selected publications and creative works (Research Outputs)

  • Jamieson, S. M. F., Gu, Y., Manesh, D. M., El-Hoss, J., Jing, D., MacKenzie, K. L., ... Benito, J. (2014). A novel fluorometric assay for aldo-keto reductase 1C3 predicts metabolic activation of the nitrogen mustard prodrug PR-104A in human leukaemia cells. Biochemical Pharmacology, 88 (1), 36-45. 10.1016/j.bcp.2013.12.019
    URL: http://hdl.handle.net/2292/26208
    Other University of Auckland co-authors: Adam Patterson, Jeff Smaill, Stephen Jamieson, Stefan Bohlander
  • Chowdhury, G., Sarkar, U., Pullen, S., Wilson, W. R., Rajapakse, A., Fuchs-Knotts, T., & Gates, K. S. (2012). DNA Strand Cleavage by the Phenazine Di-N-oxide Natural Product Myxin under Both Aerobic and Anaerobic Conditions. CHEMICAL RESEARCH IN TOXICOLOGY, 25 (1), 197-206. 10.1021/tx2004213
  • Singleton, R. S., Guise, C. P., Ferry, D. M., Pullen, S. M., Dorie, M. J., Brown, J. M., ... Wilson, W. R. (2009). DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity. CANCER RESEARCH, 69 (9), 3884-3891. 10.1158/0008-5472.CAN-08-4023
    Other University of Auckland co-authors: Adam Patterson, Rachelle Singleton
  • Patterson, A. V., Ferry, D. M., Edmunds, S. J., Gu, Y., Singleton, R. S., Patel, K., ... Atwell, G. J. (2007). Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104. CLINICAL CANCER RESEARCH, 13 (13), 3922-3932. 10.1158/1078-0432.CCR-07-0478
    URL: http://hdl.handle.net/2292/9252
    Other University of Auckland co-authors: Bill Denny, Kevin Hicks, Adam Patterson, Yongchuan Gu, Rachelle Singleton
  • Wilson, W. R., Hicks, K. O., Pullen, S. M., Ferry, D. M., Helsby, N. A., & Patterson, A. V. (2007). Bystander effects of bioreductive drugs: Potential for exploiting pathological tumor hypoxia with dinitrobenzamide mustards. RADIATION RESEARCH, 167 (6), 625-636. 10.1667/RR0807.1
    Other University of Auckland co-authors: Kevin Hicks, Nuala Helsby, Adam Patterson
  • Atwell, G. J., Yang, S., Pruijn, F. B., Pullen, S. M., Hogg, A., Patterson, A. V., ... Denny, W. A. (2007). Synthesis and structure-activity relationships for 2,4-dinitrobenzamide-5-mustards as prodrugs for the Escherichia coli nfsB nitroreductase in gene therapy. JOURNAL OF MEDICINAL CHEMISTRY, 50 (6), 1197-1212. 10.1021/jm061062o
    URL: http://hdl.handle.net/2292/12436
    Other University of Auckland co-authors: Frederik Pruijn, Bill Denny, Adam Patterson
  • Helsby, N. A., Atwell, G. J., Yang, S. J., Palmer, B. D., Anderson, R. F., Pullen, S. M., ... Denny, W. A. (2004). Aziridinyldinitrobenzamides: Synthesis and structure-activity relationships for activation by E-coli nitroreductase. JOURNAL OF MEDICINAL CHEMISTRY, 47 (12), 3295-3307. 10.1021/jm0498699
    Other University of Auckland co-authors: Nuala Helsby, Brian Palmer, Bob Anderson, Bill Denny
  • Helsby, N. A., Ferry, D. M., Patterson, A. V., Pullen, S. M., & Wilson, W. R. (2004). 2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT. BRITISH JOURNAL OF CANCER, 90 (5), 1084-1092. 10.1038/sj.bjc.6601612
    Other University of Auckland co-authors: Nuala Helsby, Adam Patterson

Contact details

Primary office location

M&HS BUILDING 504 - Bldg 504
Level 0, Room 015
85 PARK RD
GRAFTON
AUCKLAND 1023
New Zealand