Dr Timothy Angeli
BSE, MSE Mich., PhD
Tim Angeli is a Senior Reseach Fellow with the Gastrointestinal (GI) Research Group at the Auckland Bioengineering Institute (ABI). He is currently supported by the Rutherford Discovery Fellowship from the Royal Society of New Zealand. His research focuses on in vivo measurement and monitoring of GI electrophysiology, with a specific focus on developing new diagnostic devices and interventional therapeutics for functional gastrointestinal disorders.
Tim originally joined the GI Research Group at the ABI in December 2009 as a PhD student. His PhD research investigated the underlying electrophysiological control of the small intestine using high-resolution electrical mapping, and he received his PhD in early 2014.
Prior to joining the ABI in New Zealand, Tim attended the University of Michigan, USA, where he graduated with his Bachelor of Science in Engineering (2008, Magna Cum Laude honours) and Master of Science in Engineering (2009), both in Biomedical Engineering. He investigated new methods of drug delivery based on the human body's natural immune response for his Master's research, and also worked at a biotechnology company where he was involved in the research and development of a bioartificial kidney.
Research | Current
Tim is currently focused on developing new technologies for mapping, monitoring, and modulating gastrointestinal (GI) electrical activity, which is a vital controlling mechanism of digestion. His work is largely conducted across the fields of bioengineering, physiology, and medicine, with a specific aim of achieving new levels of clinical understanding for currently under-defined GI disorders, as well as developing new electrophysiologically-based diagnostics and therapeutics for those disorders.
- Modelling the Gastrointestinal System, Auckland Bioengineering Institute
- Diagnosis and Therapy of Gastric Dysrhythmias, MedTech Centre of Research Excellence
Alexander Chan, Development of an analysis pipeline for endoscopic gastric electrical mapping.
Tim Wang, Advances in the investigation and management of post-operative gastric arrhythmias.
Zahra Aghababaie, Targeted ablation therapy for treatment of gastrointestinal dysrhythmias.
Nova Belle Pavel Nagalakshmi, Defining the consistency of gastric slow wave signal morphology.
Kiara Miller, Slow wave mapping of the rabbit small intestine, ceacum, and colon.
Abhishek Kamat, Determining the effects of electrode diameter and protrusion on signal morphology of gastrointestinal bioelectrical recordings.
Ashley Abraham, Quantification of high-resolution rabbit intestine slow wave dynamics.
- 2019-2023: Rutherford Discovery Fellowship, Royal Society of New Zealand.
- 2017-2018: Edith C. Coan Postdoctoral Research Fellowship, Auckland Medical Research Foundation, NZ.
- 2017: Early Career Research Excellence Award, University of Auckland, NZ.
- 2016: Vice Chancellor's Research Excellence Award, University of Auckland, NZ.
- 2016: Young Investigator Award for Best Poster Presentation, American Gastroenterological Association, USA.
- 2015: Best Paper / Presentation Award, NZ Society of Gastroenterology Conference, NZ.
- 2013: Distinguished Young Investigator Award for Best Clinical Presentation, Neurogastroenterology and Motility Conference, USA.
- 2013: Young Investigator Award for Top Abstract, Neurogastroenterology and Motility Conference, USA.
- 2012: R.H.T. Bates Postgraduate Scholarship, Royal Society of NZ.
- 2011: Baxter Healthcare Young Investigator Award for Best Presentation, New Zealand Society of Gastroenterology Conference, NZ.
- 2011: First Place, 'Exposure' Postgraduate Research Oral Presentation Competition, University of Auckland, NZ.
- 2011: Best Presentation, Riddet Institute Student Colloquium, NZ.
- 2010: 'Chiasma i-Volve' Award for Best Biotechnology Entry, 'SPARK' Entrepreneurship Ideas Challenge, University of Auckland, NZ.
- 2009-2012: Earle Food Research Scholar, Riddet Institute, NZ.
- 2009: James B. Angell Scholar, University of Michigan, USA.
- 2008: Magna Cum Laude Graduation Honours, University of Michigan, USA.
Areas of expertise
- Biomedical Engineering
- Gastrointestinal Motility
- Translational Experimentation
- Experimental Physiology
Academic Service (Present)
- 2018-Present: Research Committee Member, Auckland Bioengineering Institute
- 2018-Present: Human Ethics Committee Member, Auckland Bioengineering Institute
- 2016-Present: Social Committee Member, Auckland Bioengineering Institute
- 2015-Present: Prospective Student Interviewer, Hometown Alumni Involvement Link ('HAIL'), University of Michigan, College of Engineering
- 2017-Present: Australasian Neurogastroenterology and Motility Association (ANGMA)
- 2016-Present: Auckland Medical Research Foundation (AMRF)
- 2015-Present: American Neurogastroenterology and Motility Society (ANMS)
- 2015-Present: International Gastrointestinal Electrophysiology Society (iGES)
- 2010-Present: New Zealand Society of Gastroenterology (NZSG)
- 2010-Present: Physiological Society of New Zealand (PSNZ)
- 2011: Institute of Electronics and Electrical Engineers (IEEE)
Selected publications and creative works (Research Outputs)
- Paskaranandavadivel, N., Angeli, T. R., Manson, T., Stocker, A., McElmurray, L., O'Grady G, ... Cheng, L. K. (2019). Multi-day, multi-sensor ambulatory monitoring of gastric electrical activity. Physiological measurement, 40 (2)10.1088/1361-6579/ab0668
Other University of Auckland co-authors: Nira Paskaranandavadivel
- O'Grady G, Angeli, T. R., Paskaranandavadivel, N., Erickson, J. C., Wells, C. I., Gharibans, A. A., ... Du, P. (2019). Methods for High-Resolution Electrical Mapping in the Gastrointestinal Tract. IEEE reviews in biomedical engineering, 12, 287-302. 10.1109/rbme.2018.2867555
Other University of Auckland co-authors: Nira Paskaranandavadivel, Greg O'Grady, Armen Gharibans
- Angeli, T. R., O'Grady G, Vather, R., Bissett, I. P., & Cheng, L. K. (2018). Intra-operative high-resolution mapping of slow wave propagation in the human jejunum: Feasibility and initial results. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 30 (7)10.1111/nmo.13310
Other University of Auckland co-authors: Greg O'Grady, Ian Bissett
- Wang, R., Abukhalaf, Z., Javan-Khoshkholgh, A., Wang, T. H.-H., Sathar, S., Du, P., ... Paskaranandavadivel, N. (2018). A Miniature Configurable Wireless System for Recording Gastric Electrophysiological Activity and Delivering High-Energy Electrical Stimulation. IEEE Journal on Emerging and Selected Topics in Circuits and Systems, 8 (2), 221-229. 10.1109/JETCAS.2018.2812105
Other University of Auckland co-authors: Shameer Sathar, Greg O'Grady, Nira Paskaranandavadivel
- Erickson, J. C., Hayes, J. A., Bustamante, M., Joshi, R., Rwagaju, A., Paskaranandavadivel, N., & Angeli, T. R. (2018). Intsy: a low-cost, open-source, wireless multi-channel bioamplifier system. Physiological measurement, 39 (3)10.1088/1361-6579/aaad51
Other University of Auckland co-authors: Nira Paskaranandavadivel
- Angeli, T. R., & O'Grady G (2018). Challenges in defining, diagnosing, and treating diabetic gastroparesis. Journal of diabetes and its complications, 32 (2), 127-128. 10.1016/j.jdiacomp.2017.11.006
Other University of Auckland co-authors: Greg O'Grady
- Mayne, T. P., Paskaranandavadivel, N., Erickson, J. C., OGrady, G., Cheng, L. K., & Angeli, T. R. (2018). Improved visualization of gastrointestinal slow wave propagation using a novel wavefront-orientation interpolation technique. IEEE Trans Biomed Eng, 65 (2), 319-326. 10.1109/TBME.2017.2764945
Other University of Auckland co-authors: Nira Paskaranandavadivel, Greg O'Grady
- Berry, R., Cheng, L. K., Du, P., Paskaranandavadivel, N., Angeli, T. R., Mayne, T., ... O'Grady G (2017). Patterns of abnormal gastric pacemaking after sleeve gastrectomy defined by laparoscopic high-resolution electrical mapping. Obesity Surgery, 27 (8), 1929-1937. 10.1007/s11695-017-2597-6
Other University of Auckland co-authors: Nira Paskaranandavadivel, Greg O'Grady, Leo Cheng, Peng Du