Dr Tim Angeli
BSE, MSE Mich., PhD
Tim Angeli is a Reseach Fellow with the Gastrointestinal (GI) Research Group at the Auckland Bioengineering Institute (ABI). He is currently supported by the Edith C. Coan Postdoctoral Fellowship from the Auckland Medical Research Foundation. His research focuses on in vivo measurement and monitoring of GI electrophysiology, with a specific focus on developing new diagnostic devices and interventional therapeutics for functional gastrointestinal disorders.
Tim originally joined the GI Research Group at the ABI in December 2009 as a PhD student. He investigated the underlying electrophysiological control of the small intestine using innovative methods of high-resolution electrical mapping, and received his PhD in early 2014.
Prior to joining the ABI in New Zealand, Tim attended the University of Michigan, USA, where he graduated with his Bachelor of Science in Engineering (2008, Magna Cum Laude honours) and Master of Science in Engineering (2009), both in Biomedical Engineering. He investigated innovative methods of drug delivery based on the human body's natural immune response for his Master's research, and also worked at a biotechnology company where he was involved in the research and development of a bioartificial kidney.
Research | Current
Tim is currently focused on developing new technologies for mapping, monitoring, and modulating gastrointestinal (GI) electrical activity, which is a vital controlling mechanism of digestion. His work is largely conducted across the fields of bioengineering, physiology, and medicine, with a specific aim of achieving new levels of clinical understanding for currently under-defined GI disorders, as well as developing new electrophysiologically-based diagnostics and therapeutics for those disorders.
- Modelling the Gastrointestinal System, Auckland Bioengineering Institute
- Diagnosis and Therapy of Gastric Dysrhythmias, MedTech Centre of Research Excellence
Tim Wang, Advances in the investigation and management of post-operative gastric arrhythmias.
Zahra Aghababaie, Targeted ablation therapy for treatment of gastrointestinal dysrhythmias.
Abhishek Kamat, Determining the effects of electrode diameter and protrusion on signal morphology of gastrointestinal bioelectrical recordings.
Ashley Abraham, Quantification of high-resolution rabbit intestine slow wave dynamics.
- 2017-2018: Edith C. Coan Postdoctoral Research Fellowship, Auckland Medical Research Foundation, NZ.
- 2017: Early Career Research Excellence Award, University of Auckland, NZ.
- 2016: Vice Chancellor's Research Excellence Award, University of Auckland, NZ.
- 2016: Young Investigator Award for Best Poster Presentation, American Gastroenterological Association, USA.
- 2015: Best Paper / Presentation Award, NZ Society of Gastroenterology Conference, NZ.
- 2013: Distinguished Young Investigator Award for Best Clinical Presentation, Neurogastroenterology and Motility Conference, USA.
- 2013: Young Investigator Award for Top Abstract, Neurogastroenterology and Motility Conference, USA.
- 2012: R.H.T. Bates Postgraduate Scholarship, Royal Society of NZ.
- 2011: Baxter Healthcare Young Investigator Award for Best Presentation, New Zealand Society of Gastroenterology Conference, NZ.
- 2011: First Place, 'Exposure' Postgraduate Research Oral Presentation Competition, University of Auckland, NZ.
- 2011: Best Presentation, Riddet Institute Student Colloquium, NZ.
- 2010: 'Chiasma i-Volve' Award for Best Biotechnology Entry, 'SPARK' Entrepreneurship Ideas Challenge, University of Auckland, NZ.
- 2009-2012: Earle Food Research Scholar, Riddet Institute, NZ.
- 2009: James B. Angell Scholar, University of Michigan, USA.
- 2008: Magna Cum Laude Graduation Honours, University of Michigan, USA.
Areas of expertise
- Biomedical Engineering
- Gastrointestinal Motility
- Translational Experimentation
Academic Service (Present)
- 2016-Present: Social Committee Member, Auckland Bioengineering Institute
- 2015-Present: Prospective Student Interviewer, Hometown Alumni Involvement Link ('HAIL'), University of Michigan, College of Engineering
- 2013-Present: Early Career Research Representative, Auckland Bioengineering Institute
- 2017-Present: Australasian Neurogastroenterology and Motility Association (ANGMA)
- 2016-Present: Auckland Medical Research Foundation (AMRF)
- 2015-Present: American Neurogastroenterology and Motility Society (ANMS)
- 2015-Present: International Gastrointestinal Electrophysiology Society (iGES)
- 2010-Present: New Zealand Society of Gastroenterology (NZSG)
- 2010-Present: Physiological Society of New Zealand (PSNZ)
- 2011: Institute of Electronics and Electrical Engineers (IEEE)
Selected publications and creative works (Research Outputs)
- O'Grady G, Paskaranandavadivel, N., Du, P., Angeli, T., Erickson, J. C., & Cheng, L. K. (2017). Correct techniques for extracellular recordings of electrical activity in gastrointestinal muscle. Nature reviews. Gastroenterology & hepatology, 14 (6)10.1038/nrgastro.2017.15
Other University of Auckland co-authors: Greg O'Grady, Nira Paskaranandavadivel, Peng Du
- Angeli, T. R., Du, P., Paskaranandavadivel, N., Sathar, S., Hall, A., Asirvatham, S. J., ... O'Grady G (2017). High-resolution electrical mapping of porcine gastric slow-wave propagation from the mucosal surface. Neurogastroenterology and Motility, 29 (5).10.1111/nmo.13010
Other University of Auckland co-authors: Nira Paskaranandavadivel, John Windsor, Greg O'Grady, Leo Cheng, Peng Du, Shameer Sathar
- Berry, R., Cheng, L. K., Du, P., Paskaranandavadivel, N., Angeli, T. R., Mayne, T., ... O'Grady G (2017). Patterns of Abnormal Gastric Pacemaking After Sleeve Gastrectomy Defined by Laparoscopic High-Resolution Electrical Mapping. Obesity surgery10.1007/s11695-017-2597-6
Other University of Auckland co-authors: Nira Paskaranandavadivel, Greg O'Grady, Leo Cheng, Peng Du
- Mayne, T. P., Paskaranandavadivel, N., Erickson, J. C., O Grady, G., Cheng, L. K., & Angeli, T. R. (2017). Improved visualization of gastrointestinal slow wave propagation using a novel wavefront-orientation interpolation technique. IEEE Transactions on Biomedical Engineering, 1-1. 10.1109/TBME.2017.2764945
- Wang, T.-H., Du, P., Angeli, T., Paskaranandavadivel, N., Erickson, J., Abell, T., ... O'Grady G (2017). Relationships between gastric slow wave frequency, velocity, and extracellular amplitude studied by a joint experimental-theoretical approach. Neurogastroenterology and Motility10.1111/nmo.13152
Other University of Auckland co-authors: Nira Paskaranandavadivel, Greg O'Grady, Peng Du
- Angeli, T. R., Du, P., Midgley, D., Paskaranandavadivel, N., Sathar, S., Lahr, C., ... O'Grady G (2016). Acute Slow Wave Responses to High-Frequency Gastric Electrical Stimulation in Patients With Gastroparesis Defined by High-Resolution Mapping. Neuromodulation, 19 (8), 864-871. 10.1111/ner.12454
Other University of Auckland co-authors: Nira Paskaranandavadivel, Leo Cheng, Greg O'Grady, Peng Du, Shameer Sathar
- Berry, R., Miyagawa, T., Paskaranandavadivel, N., Du, P., Angeli, T. R., Trew, M. L., ... Cheng, L. K. (2016). Functional physiology of the human terminal antrum defined by high-resolution electrical mapping and computational modeling. American journal of physiology. Gastrointestinal and liver physiology, 311 (5), G895-G902. 10.1152/ajpgi.00255.2016
Other University of Auckland co-authors: John Windsor, Mark Trew, Greg O'Grady, Nira Paskaranandavadivel, Leo Cheng, Peng Du
- Erickson, J. C., Putney, J., Hilbert, D., Paskaranandavadivel, N., Cheng, L. K., OGrady, G., & Angeli, T. R. (2016). Iterative Covariance-Based Removal of Time-Synchronous Artifacts: Application to Gastrointestinal Electrical Recordings. IEEE transactions on bio-medical engineering, 63 (11), 2262-2272. 10.1109/tbme.2016.2521764
Other University of Auckland co-authors: Nira Paskaranandavadivel, Leo Cheng, Greg O'Grady