Dr Tim Angeli

BSE, MSE Mich., PhD

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Senior Research Fellow

Biography

Tim Angeli is a Rutherford Discovery Fellow and Senior Research Fellow with the Gastrointestinal (GI) Research Group at the Auckland Bioengineering Institute (ABI). His research focuses on in vivo measurement and monitoring of GI electrophysiology, with a specific focus on developing new diagnostic devices and interventional therapeutics for functional GI disorders. He research is currently supported by the Health Research Council of New Zealand, and a Rutherford Discovery Fellowship from the Royal Society of New Zealand. 

Tim originally joined the GI Research Group at the ABI in December 2009 as a PhD student. His PhD research investigated the underlying electrophysiological control of the small intestine using high-resolution electrical mapping, and he received his PhD in early 2014.

Prior to joining the ABI in New Zealand, Tim attended the University of Michigan, USA, where he graduated with his Bachelor of Science in Engineering (2008) and Master of Science in Engineering (2009), both in Biomedical Engineering. He investigated new methods of drug delivery based on the human body's natural immune response for his Master's research, and also worked at a biotechnology company where he was involved in the research and development of a bioartificial kidney.

Research | Current

Tim is currently focused on developing new technologies for mapping, monitoring, and modulating gastrointestinal (GI) electrical activity, which is a vital controlling mechanism of digestion. His work is largely conducted across the fields of bioengineering, physiology, and medicine, with a specific aim of achieving new levels of clinical understanding for currently under-defined GI disorders, as well as developing new electrophysiologically-based diagnostics and therapeutics for those disorders.
 

Project links

International Collaborations

Postgraduate supervision

Graduate student positions available! Dr Angeli has a number of funded Masters and PhD positions currently available. If you are a high-achieving student interested in a Masters or PhD in biomedical engineering, please contact Dr Angeli for details (t.angeli@auckland.ac.nz). 

Current PhD Students:
Alexander Chan, 2018-present, Development of an analysis pipeline for endoscopic gastric electrical mapping.
Zahra Aghababaie, 2018-present, Targeted ablation therapy for treatment of gastrointestinal dysrhythmias.
Tim Wang, 2017-present (part-time), Advances in the investigation and management of post-operative gastric arrhythmias.

Completed ME Students:
Nova Belle Pavel Nagalakshmi, 2020, Defining the consistency of gastric slow wave signal morphology.
Kiara Miller, 2020, Slow wave mapping of the rabbit small intestine, ceacum, and colon.
Abhishek Kamat, 2019, Determining the effects of electrode diameter and protrusion on signal morphology of gastrointestinal bioelectrical recordings. 
Ashley Abraham, 2019, Quantification of high-resolution rabbit intestine slow wave dynamics.

Distinctions/Honours

  • 2019-2023: Rutherford Discovery Fellowship, Royal Society of New Zealand.
  • 2017-2018: Edith C. Coan Postdoctoral Research Fellowship, Auckland Medical Research Foundation, NZ.
  • 2017: Early Career Research Excellence Award, University of Auckland, NZ.
  • 2016: Vice Chancellor's Research Excellence Award, University of Auckland, NZ.
  • 2016: Young Investigator Award for Best Poster Presentation, American Gastroenterological Association, USA.
  • 2015: Best Paper / Presentation Award, NZ Society of Gastroenterology Conference, NZ.
  • 2013: Distinguished Young Investigator Award for Best Clinical Presentation, Neurogastroenterology and Motility Conference, USA.
  • 2013: Young Investigator Award for Top Abstract, Neurogastroenterology and Motility Conference, USA.
  • 2012: R.H.T. Bates Postgraduate Scholarship, Royal Society of NZ.
  • 2011: Baxter Healthcare Young Investigator Award for Best Presentation, New Zealand Society of Gastroenterology Conference, NZ.
  • 2011: First Place, 'Exposure' Postgraduate Research Oral Presentation Competition, University of Auckland, NZ.
  • 2011: Best Presentation, Riddet Institute Student Colloquium, NZ.
  • 2010: 'Chiasma i-Volve' Award for Best Biotechnology Entry, 'SPARK' Entrepreneurship Ideas Challenge, University of Auckland, NZ.
  • 2009-2012: Earle Food Research Scholar, Riddet Institute, NZ.
  • 2009: James B. Angell Scholar, University of Michigan, USA.
  • 2008: Magna Cum Laude Graduation Honours, University of Michigan, USA.

Responsibilities

Areas of expertise

  • Biomedical Engineering
  • Electrophysiology
  • Gastrointestinal Motility
  • Translational Experimentation
  • Experimental Physiology

Committees/Professional groups/Services

Academic Service (Present)

Professional Societies

  • 2019-Present: Institute of Electronics and Electrical Engineers (IEEE)
  • 2019-Present: Engineering in Medicine and Biology Society (EMBS)
  • 2017-Present: Australasian Neurogastroenterology and Motility Association (ANGMA)
  • 2016-Present: Auckland Medical Research Foundation (AMRF)
  • 2015-Present: American Neurogastroenterology and Motility Society (ANMS)
  • 2015-Present: International Gastrointestinal Electrophysiology Society (iGES)
  • 2010-Present: New Zealand Society of Gastroenterology (NZSG)
  • 2010-Present: Physiological Society of New Zealand (PSNZ)

Selected publications and creative works (Research Outputs)

  • Kamat, A. A., Paskaranandavadivel, N., Alighaleh, S., Cheng, L. K., & Angeli, T. R. (2020). Effects of Electrode Diameter and Contact Material on Signal Morphology of Gastric Bioelectrical Slow Wave Recordings.. Annals of biomedical engineering. 10.1007/s10439-020-02457-5
    Other University of Auckland co-authors: Nira Paskaranandavadivel, Saeed Alighaleh
  • Cherian Abraham, A., Cheng, L. K., Angeli, T. R., Alighaleh, S., & Paskaranandavadivel, N. (2019). Dynamic slow-wave interactions in the rabbit small intestine defined using high-resolution mapping. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 31 (9)10.1111/nmo.13670
    Other University of Auckland co-authors: Nira Paskaranandavadivel, Saeed Alighaleh
  • Wang, T. H.-H., Angeli, T. R., Beban, G., Du, P., Bianco, F., Gibbons, S. J., ... O'Grady G (2019). Slow-wave coupling across a gastroduodenal anastomosis as a mechanism for postsurgical gastric dysfunction: evidence for a "gastrointestinal aberrant pathway". American journal of physiology. Gastrointestinal and liver physiology, 317 (2), G141-G146. 10.1152/ajpgi.00002.2019
    Other University of Auckland co-authors: John Windsor, Greg O'Grady
  • Kuruppu, S., Cheng, L. K., Angeli, T. R., Avci, R., & Paskaranandavadivel, N. (2019). A Framework for Spatiotemporal Analysis of Gastrointestinal Spike Burst Propagation.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 10.1109/embc.2019.8856924
    Other University of Auckland co-authors: Nira Paskaranandavadivel
  • Aghababaie, Z., Chan, C.-H. A., Paskaranandavadivel, N., Beyder, A., Farrugia, G., Asirvatham, S., ... Angeli, T. R. (2019). Feasibility of High-Resolution Electrical Mapping for Characterizing Conduction Blocks Created by Gastric Ablation.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 10.1109/embc.2019.8856406
    Other University of Auckland co-authors: Nira Paskaranandavadivel, Greg O'Grady
  • Chan, C.-H. A., Aghababaie, Z., Paskaranandavadivel, N., Cheng, L. K., & Angeli, T. R. (2019). Methods for Visualization of Gastric Endoscopic Mapping Data From Three-Dimensional, Non-Uniform Electrode Arrays.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 10.1109/embc.2019.8857158
    Other University of Auckland co-authors: Nira Paskaranandavadivel
  • Han, H., Cheng, L. K., Angeli, T. R., & Paskaranandavadivel, N. (2019). Detection of Monophasic Slow-wave Activation Phase Using Wavelet Decomposition.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 10.1109/embc.2019.8856736
    Other University of Auckland co-authors: Henry Han, Nira Paskaranandavadivel
  • Paskaranandavadivel, N., Angeli, T. R., Manson, T., Stocker, A., McElmurray, L., O'Grady G, ... Cheng, L. K. (2019). Multi-day, multi-sensor ambulatory monitoring of gastric electrical activity. Physiological measurement, 40 (2)10.1088/1361-6579/ab0668
    Other University of Auckland co-authors: Nira Paskaranandavadivel, Greg O'Grady, Tabitha Manson

Identifiers

Contact details

Primary office location

AUCKLAND BIOENGINEERING HOUSE - Bldg 439
Level 8, Room 817
70 SYMONDS ST
GRAFTON
AUCKLAND 1010
New Zealand

Web links