Dr Vicky Wang

BE(Hons) PhD

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Research Fellow

Biography

Vicky Wang graduated from the University of Auckland with a Bachelor of Engineering (specialising in Biomedical Engineering) in 2006, and commenced working towards a doctorate at the Auckland Bioengineering Institute in 2007 under the supervision of Professors Martyn Nash and Alistair Young.

Her doctoral thesis focused on constructing a mathematical model of the heart - especially the left ventricle (LV) - from information obtained from two cardiac magnetic resonance imaging (MRI) techniques: tagged MRI and diffusion tensor MRI. This biophysical model can be used to simulate ventricular mechanics and consequently estimate myocardial mechanical properties.

Models between healthy and diseased cases (i.e. heart failure or diabetes) will allow more insights into the underlying mechanisms of these diseases. This framework can also provide information on regional distribution of stress and strain as well as local energy consumption. Works related to this project have been published in LNCS MICCAI 2008 and Medical Image Analysis.

On completion of her PhD, Vicky became a Research Fellow.
 

Research | Current

Vicky Wang's post-doctoral research focuses primarily on developing integrated physiological models of the heart that can provide insight into cardiac mechanics on an individualised basis. This type of research aims to improve our understanding of the underlying basis for mechanisms that affect cardiac muscle stiffness, and to help with clinical diagnosis for patients with heart failure.
 

Research groups

Teaching | Current

BIOMENG 321 Continuum Mechanics

Selected publications and creative works (Research Outputs)

  • Hasaballa, A. I., Wang, V. Y., Sands, G. B., Wilson, A. J., Young, A. A., LeGrice, I. J., & Nash, M. P. (2019). Microstructurally Motivated Constitutive Modeling of Heart Failure Mechanics. Biophysical journal, 117 (12), 2273-2286. 10.1016/j.bpj.2019.09.038
    Other University of Auckland co-authors: Gregory Sands, Alistair Young, Ian LeGrice, Martyn Nash
  • Zhao, D., Gilbert, K., McDougal, C. R., Wang, V. Y., Houle, H., Doughty, R., ... Nash, M. P. (2019). Personalised shape models of the left ventricle from 3D echocardiography: an initial comparison to cardiac magnetic resonance imaging. Paper presented at Congress of the European-Society-of-Cardiology (ESC) / World Congress of Cardiology, Paris, FRANCE. 31 August - 4 September 2019. EUROPEAN HEART JOURNAL. (pp. 1).
    Other University of Auckland co-authors: Martyn Nash
  • Zhang, Y., Wang, V. Y., Morgan, A. E., Kim, J., Handschumacher, M. D., Moskowitz, C. S., ... Weinsaft, J. W. (2019). Mechanical effects of MitraClip on leaflet stress and myocardial strain in functional mitral regurgitation - A finite element modeling study. PloS one, 14 (10)10.1371/journal.pone.0223472
  • Wang, Z. J., Wang, V. Y., Bradley, C. P., Nash, M. P., Young, A. A., & Cao, J. J. (2018). Left Ventricular Diastolic Myocardial Stiffness and End-Diastolic Myofibre Stress in Human Heart Failure Using Personalised Biomechanical Analysis. Journal of cardiovascular translational research, 11 (4), 346-356. 10.1007/s12265-018-9816-y
    Other University of Auckland co-authors: Christopher Bradley, Martyn Nash, Alistair Young
  • Wang, V. Y., Hussan, J. R., Yousefi, H., Bradley, C. P., Hunter, P. J., & Nash, M. P. (2017). Modelling cardiac tissue growth and remodelling. Journal of Elasticity, 129 (1-2), 283-305. 10.1007/s10659-017-9640-7
    URL: http://hdl.handle.net/2292/42638
    Other University of Auckland co-authors: Jagir Hussan, Christopher Bradley, Peter Hunter, Martyn Nash
  • Wilson, A. J., Wang, V. Y., Sands, G. B., Young, A. A., Nash, M. P., & LeGrice, I. J. (2017). Increased cardiac work provides a link between systemic hypertension and heart failure. Physiological Reports, 5 (1)10.14814/phy2.13104
    URL: http://hdl.handle.net/2292/35214
    Other University of Auckland co-authors: Gregory Sands, Alistair Young, Martyn Nash, Ian LeGrice
  • Hasaballa, A. I., Sands, G. B., Wilson, A. J., Young, A. A., Wang, V. Y., LeGrice, I. J., & Nash, M. P. (2017). Three-dimensional quantification of myocardial collagen morphology from confocal images. In M. Pop, G. Wright (Eds.) Functional Imaging and Modelling of the Heart: 9th International Conference, FIMH 2017, Toronto, ON, Canada, June 11-13, 2017, Proceedings, 10263, 3-12. Cham: Springer International Publishing AG. 10.1007/978-3-319-59448-4_1
    URL: http://hdl.handle.net/2292/35947
    Other University of Auckland co-authors: Gregory Sands, Alistair Young, Ian LeGrice, Martyn Nash
  • Wang, V. Y., Casta, C., Zhu, Y. M., Cowan, B. R., Croisille, P., Young, A. A., ... Nash, M. P. (2016). Image-based investigation of human in vivo myofibre strain. IEEE Transactions on Medical Imaging, 35 (11), 2486-2496. 10.1109/TMI.2016.2580573
    URL: http://hdl.handle.net/2292/32316
    Other University of Auckland co-authors: Alistair Young, Martyn Nash

Identifiers

Contact details

Primary office location

UNISERVICES HOUSE - Bldg 439
Level 7, Room 721
70 SYMONDS ST
AUCKLAND 1010
New Zealand

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